| Aug 21, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 27.230K | $50.00 | $1.4M |
| Aug 18, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 32.676K | $45.00 | $1.5M |
| Aug 17, 2026 | Campbell Rogers | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $30.11 | $205K |
| Aug 14, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 15.560K | $39.06 | $608K |
| Aug 10, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 22.562K | $28.31 | $639K |
| Jul 15, 2026 | Campbell Rogers | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $22.36 | $62K |
| Jul 10, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 22.562K | $27.75 | $626K |
| Jun 24, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 38.900K | $35.00 | $1.4M |
| Jun 10, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 22.562K | $28.50 | $643K |
| May 18, 2026 | Campbell Rogers | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $23.67 | $86K |
| May 11, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 22.562K | $29.12 | $657K |
| Apr 28, 2026 | Bain Capital Life Sciences Investors LLC, Bain Capital Life Sciences III General Partner LLC, Bain Capital Life Sciences Fund III LP, BCLS Fund III Investments GP LLC, BCLS Fund III Investments LP | — | SELL | 2.000M | $29.45 | $58.9M |
| Apr 10, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 22.562K | $26.72 | $603K |
| Apr 1, 2026 | Campbell Rogers | CHIEF MEDICAL OFFICER | SELL-OPTIONS | 2.484K | $13.44 | $1.4M |
| Mar 19, 2026 | Campbell Rogers | CHIEF MEDICAL OFFICER | SELL-OPTIONS | 2.484K | $13.96 | $1.5M |
| Mar 18, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 9.725K | $25.00 | $243K |
| Mar 6, 2026 | CM John Farquhar | CHIEF EXECUTIVE OFFICER | SELL | 10.206K | $19.41 | $248K |
| Mar 5, 2026 | Julie Cullivan | DIRECTOR | SELL | 9.122K | $25.00 | $228K |
