Gainers

• Array BioPharma Inc. (NASDAQ:ARRY) rose 59% to $47.05 in pre-market trading after Pfizer Inc. (NYSE:PFE) announced plans to acquire Array BioPharma for $48 per share in cash.
• Daktronics, Inc (NASDAQ:DAKT) rose 19.6% to $7.50 in pre-market trading.
• Orgenesis Inc. (NASDAQ:ORGS) rose 18.9% to $5.10 in pre-market trading after the company disclosed that it has been granted FDA Orphan Drug designation for its Autologous Insulin Producing cells in the treatment of Severe hypoglycemia-prone diabetes resulting from total pancreatectomy.
• Castle Brands Inc (NYSE:ROX) rose 17.2% to $0.60 in pre-market trading following Q4 results. Castle Brands posted Q4 earnings of $0.05 per share on sales of $29.89 million.
• Calithera Biosciences, Inc. (NASDAQ:CALA) rose 15.6% to $6.02 in pre-market trading after reporting 'positive' topline results in randomized Phase 2 ENTRATA study of telaglenastat with everolimus in renal cell carcinoma.
• Aclaris Therapeutics, Inc. (NASDAQ:ACRS) rose 15.6% to $5.40 in pre-market trading after reporting positive 6-month results from a Phase 2 open-label clinical trial of ATI-502 topical in patients with androgenetic alopecia.
• Globant S.A. (NYSE:GLOB) rose 12.6% to $112.00 in pre-market trading.
• Riot Blockchain, Inc. (NASDAQ:RIOT) rose 11% to $3.03 in pre-market trading after gaining 5.41% on Friday.
• Uniqure NV (NASDAQ:QURE) rose 8.9% to $79.00 in pre-market trading following Bloomberg report that the company is exploring options including a potential sale.
• Antero Midstream Corporation (NYSE:AM) gained 8% to $12.50 in pre-market trading after falling 5.24% on Friday.
• OrganiGram Holdings Inc. (NASDAQ:OGI) shares rose 7.7% to $6.75 in pre-market trading after dropping 7.79% on Friday.
• Jazz Pharmaceuticals plc (NASDAQ:JAZZ) rose 6.6% to $139.00 in pre-market trading.
• ReWalk Robotics Ltd. (NASDAQ:RWLK) rose 6.5% to $5.55 in pre-market trading after declining 4.58% on Friday.
• Monster Beverage Corporation (NASDAQ:MNST) shares rose 5.2% to $64.50 in pre-market trading.
• Uxin Limited (NASDAQ:UXIN) rose 5% to $2.12 in pre-market trading after gaining 4.12% on Friday.

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Check out these big penny stock gainers and losers

Losers

• VBI Vaccines Inc (NASDAQ:VBIV) shares fell 31.2% to $1.30 in pre-market trading after the company reported results from its Phase 3 Study of Sci-b-vac. The trial met both co-primary endpoints but did not meet its secondary objective of non-inferiority.
• Ampio Pharmaceuticals Inc (NYSE:AMPE) fell 21.4% to $0.55 in pre-market trading after reporting a common stock offering.
• Celyad SA (NASDAQ:CYAD) fell 20.3% to $14.75 in pre-market trading.
• Bionano Genomics, Inc. (NASDAQ:BNGO) fell 13.8% to $2.50 in pre-market trading.
• Seanergy Maritime Holdings Corp. (NASDAQ:SHIP) fell 9.2% to $0.59 in pre-market trading. Seanergy Maritime reported a Q4 loss of $3.23 per share, versus a year-ago loss of $1.40 per share. Its sales declined to $16.013 million from $21.322 million.
• Genocea Biosciences, Inc. (NASDAQ:GNCA) fell 6.8% to $4.91 in pre-market trading.
• Bridgeline Digital, Inc. (NASDAQ:BLIN) fell 6.2% to $2.58 in pre-market trading.
• Seadrill Limited (NYSE:SDRL) fell 4.2% to $2.99 in pre-market trading after dropping 9.30% on Friday.
• ContraVir Pharmaceuticals, Inc. (NASDAQ:CTRV) fell 3.5% to $8.58 in pre-market trading after declining 12.07% on Friday.
• Endo International plc (NASDAQ:ENDP) fell 3.5% to $3.91 in pre-market trading after dropping 9.40% on Friday.
• NextEra Energy Partners, LP (NYSE:NEP) fell 3.3% to $45.02 in pre-market trading.
• India Globalization Capital, Inc. (NYSE:IGC) fell 4% to $1.21 in pre-market trading following Q4 results.