Psyched: Defense Dept.'s Ketamine Trial, Cybin's Psilocybin, Metabolic Disorders, Reform Update And More

Defense Dept. Funds Ketamine Study For PTSD Treatment 

A DOD Health Agency-funded adaptive platform trial for alternative treatments for PTSD will test SLS-002 on some 600 active-duty service members and veterans. The intranasal racemic ketamine was developed by biotech company Seelos Therapeutics SEEL.

The new Phase 2 study will use an adaptive platform trial design involving a 30-day screening period, a 12-week treatment period, and a four-week follow-up to assess safety, tolerability and efficacy of multiple doses of SLS-002 paired with therapy. Read more HERE.

Cybin's Novel Psilocybin Topline Data 

Next-generation psychedelics biotech Cybin Inc. CYBN released the full Phase 2 trial results of its deuterated psilocybin derivative CYB003 for Major Depressive Disorder (MDD.) Although a relatively small trial, outcomes for the novel psychedelic are so far showing strong treatment efficacy after a single dose and “a clear incremental benefit” following a second one.

See new topline follow-up data HERE.

Clearmind Medicine's Psychedelic-Based Treatment 

Clearmind Medicine Inc. CMND released results from its pre-clinical trial of the combination therapy. The treatment includes Clearmind's MEAI, a proprietary psychedelic treatment for various addictions, obesity and metabolic disorders, and depression, and SciSparc Ltd's SPRC Palmitoylethanolamide (PEA), an anti-inflammatory agent and the active ingredient of its proprietary CannAmide. Learn more HERE.

Clearmind has recently undergone a 1-for-30 reverse stock split of its issued and outstanding ordinary shares, effective starting Nov. 28, as a means to regain compliance with Nasdaq’s minimum bid price rule.

Beckley Retreats Kicks Off 2024 With New Program 

Beckley Retreats, a science-backed psilocybin retreats and holistic wellbeing company, is officially launching its Signature Program for Personal Discovery and Transformation, “an 11-week curriculum of preparation and integration support to help guests achieve the most significant benefit from their six-day psilocybin retreats” in Jamaica and the Netherlands.

Under the umbrella of Amanda Feilding’s Beckley Foundation family of brands, Beckley Retreats has access to modern psychedelic science, implementing this research into its programming and protocols and collaborating in research and datasets toward helping set a precedent and best practices for the modern use of psychedelics. Program details HERE.

Mindbloom's Mastermind Series, A Psychedelic Therapy Program

Austin-based ketamine therapy provider Mindbloom is launching its Mastermind Series, the first-of-its-kind, expert-led psychedelic therapy program for overcoming severe mental and emotional health challenges.

With a new monthly release every month, each episode was developed jointly with a leading expert in the field and combines specialized instruction with ketamine therapy to enhance neuroplasticity and enable lasting change. 

The first episode, “Recovering from Rejection and Failure,” is led by emotional health expert, psychologist and best-selling author Dr. Guy Winch who will provide “emotional first aid” and skills paired with ketamine therapy. Find out more HERE.

The Milestone Round

See Also: Last Week's Edition Of 'Psyched'

Psychedelics ETF Weekly Performance

AdvisorShares Psychedelics ETF PSIL opened Monday, November 27 at $1.43 (vs. prior weeks’ openings at $1.25 and $1.29)

On Friday, Dec. 1 it closed at $1.33 (vs. prior closings at $1.42 and $1.32.) 

Week’s highest was opening price of $1.43 (vs. prior weeks’ highests at $1.44 and $1.37.)

Week’s lowest was $1.27 on Thursday, Nov. 30 (vs. prior weeks’ lowest points at $1.25 and $1.27.)

Highest Trading Psychedelics Stocks Friday, Dec. 1 At Close

  • GH Research GHRS closed at $6.40, vs. immediately prior closings at $6.58 and $6.44.

  • COMPASS Pathways CMPS closed at $6.10, vs. prior closings at $6.46 and $6.01. 

  • Incannex Healthcare IXHL closed at $5.23, a spectacular jump from prior closings at $0.97 and $0.91

  • Clearmind Medicine CMND closed at $4.14, also an ostensible high considering prior closings at $3.10 and $3.82.

  • Mind Medicine (MindMed) MNMD closed at $3.52, vs. prior closings at $3.03 and $2.59.

  • Enveric Biosciences ENVB closed at $1.68, vs. prior closings at $1.47 and $1.52.

  • Silo Pharma SILO closed at $1.45, vs. prior closings at $1.82 and $1.50.

  • Bright Minds Biosciences DRUG closed at $1.42, vs. prior closings at $1.49 and $1.26.

  • Seelos Therapeutics SEEL closed at $1.38, vs. prior closings at $3.21 and $3.82.

  • Atai Life Sciences ATAI closed at $1.12, vs. prior closings at $1.09 and $1.11. 

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