U.S. stocks were slightly lower, with the Dow Jones index falling around 0.1% on Wednesday.

Shares of Johnson & Johnson (NYSE:JNJ) rose sharply during Wednesday's session after the company raised its FY2025 earnings guidance.

Johnson & Johnson reported a second-quarter 2025 adjusted earnings of $2.77 per share, down 1.8% year over year, beating the consensus of $2.68. The pharmaceutical giant reported sales of $23.74 billion, up 5.8% year over year and beating the consensus of $22.85 billion.

Johnson & Johnson shares jumped 6.5% to $165.24 on Wednesday.

Here are some other big stocks recording gains in today’s session.

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