U.S. indices had a mixed day of trading Wednesday as investors weigh rising COVID-19 Delta variant cases nationwide.

• The Invesco QQQ Trust Series 1 (NASDAQ:QQQ) gained 0.17% to $380.58
• The SPDR Dow Jones Industrial Average ETF Trust (NASDAQ:DIA) lost 0.10% to $353.55
• The SPDR S&P 500 ETF Trust (NASDAQ:SPY) gained 0.06% to $451.81

Here are the day's winners and losers from the Nasdaq-100, according to data from Benzinga Pro.

Moderna Inc (NASDAQ:MRNA), DexCom, Inc. (NASDAQ:DXCM) and Baidu Inc (NASDAQ:BIDU) were among the top gainers for the Nasdaq-100 Wednesday.

Autodesk, Inc. (NASDAQ:ADSK), Vertex Pharmaceuticals (NASDAQ:VRTX) and Texas Instruments (NASDAQ:TXN) were among the top losers for the Nasdaq-100.

Elsewhere On The Street

September has historically been the worst month for the stock market, so the S&P 500’s seven-month winning streak could be in jeopardy... Read More

C3.ai Inc. (NASDAQ:AI) shares were trading higher Wednesday, with the company scheduled to report second-quarter financial results after the closing bell... Read More