Denali Therapeutics Market Sentiment

Denali Therapeutics Inc

DNLINASDAQ

Trade with Public

$20.15

0.090.45%

Last update: Sep 17, 1:47 PM

Overview News Earnings Forecast Events Price Targets FinancialsSentimentOwnership Compare Options Stock Report

Denali Therapeutics Market Sentiment

Market sentiment signals for Denali Therapeutics (DNLI): analyst consensus, short interest, options flow and insider activity.

Key Signals

Analyst Consensus▲ Buy

Short Interest▲ 11.0% short float

Options Flow▲ 0.67 P/C ratio

Insider Activity▼ Net Seller (30d)

Analyst Consensus

Buy

23 analysts

Options Flow (P/C)

0.67

More calls — Bullish

329 calls · 222 puts

Avg Consensus PT

$35

+74.5%

Highest Price Target

$45

+123.3%

Jefferies

Lowest Price Target

$23

+14.1%

Wedbush

Short Interest

11.0%

Declining — Bullish

Insider Activity (30d)

Net Seller

Short Interest — % of Float

Recent Analyst Actions

Date	Firm	Analyst & Accuracy	Upside / Downside	PT Change	Action	Rating
Aug 25, 2026	B. Riley Securities	Mayank Mamtani—	+73.7%	$30 → $35	Maintained	Buy
Aug 7, 2026	UBS	Michael Yee—	+68.7%	$25 → $34	Maintained	Buy
Jul 23, 2026	Morgan Stanley	Matthew Harrison—	+78.7%	$35 → $36	Maintained	Overweight
Jul 16, 2026	Deutsche Bank	David Hoang—	+73.7%	$31 → $35	Maintained	Buy
Jul 13, 2026	JP Morgan	Jessica Fye—	+43.9%	$29	Reinstates	Overweight
May 26, 2026	Morgan Stanley	Matthew Harrison—	+73.7%	$40 → $35	Maintained	Overweight
May 14, 2026	Morgan Stanley	Matthew Harrison—	+98.5%	$42 → $40	Maintained	Overweight
May 11, 2026	BTIG	Thomas Shrader—	+93.5%	$39 → $39	Maintained	Buy
May 8, 2026	Wedbush	Laura Chico—	+14.1%	$25 → $23	Maintained	Outperform
Apr 22, 2026	Leerink Partners	Marc Goodman—	+73.7%	$40 → $35	Maintained	Outperform
Apr 7, 2026	Baird	Joel Beatty—	+68.7%	$32 → $34	Maintained	Outperform
Mar 26, 2026	Morgan Stanley	Matthew Harrison—	+108.4%	$40 → $42	Maintained	Overweight
Mar 26, 2026	Goldman Sachs	Salveen Richter—	+98.5%	$35 → $40	Maintained	Buy
Mar 26, 2026	Stifel	Paul Mattels—	+103.5%	$34 → $41	Maintained	Buy
Mar 26, 2026	Baird	Joel Beatty—	+58.8%	$29 → $32	Maintained	Outperform
Mar 26, 2026	HC Wainwright & Co.	Andrew S. Fein—	+108.4%	$32 → $42	Maintained	Buy
Mar 25, 2026	BTIG	Thomas Shrader—	+88.6%	$36 → $38	Maintained	Buy
Mar 2, 2026	BTIG	Thomas Shrader—	+78.7%	$32 → $36	Maintained	Buy
Feb 24, 2026	Wolfe Research	Rudy Li—	—	—	Initiate	Peer Perform
Feb 6, 2026	BTIG	Thomas Shrader—	+58.8%	$32 → $32	Maintained	Buy
Jan 7, 2026	UBS	Michael Yee—	+24.1%	$25	Assumes	Buy
Dec 11, 2025	Wedbush	Laura Chico—	+48.9%	$31 → $30	Maintained	Outperform
Dec 5, 2025	Wedbush	Laura Chico—	+53.8%	$30 → $31	Maintained	Outperform
Dec 5, 2025	BTIG	Thomas Shrader—	+58.8%	$32 → $32	Maintained	Buy
Nov 4, 2025	JP Morgan	Jessica Fye—	+29.0%	$24 → $26	Maintained	Overweight