Shares of DocuSign, Inc. (NASDAQ:DOCU) rose sharply in today's pre-market trading.

DocuSign will replace MDU Resources Group Inc. (NYSE:MDU) in the S&P MidCap 400, effective prior to the opening of trading on Friday, Oct. 11.

DocuSign shares jumped 5.7% to $66.35 in the pre-market trading session.

Here are some other stocks moving in pre-market trading.

Gainers

• Nature’s Miracle Holding Inc. (NASDAQ:NMHI) rose 98.8% to $0.2699 in pre-market trading after dipping 6% on Monday.
• Ontrak, Inc. (NASDAQ:OTRK) rose 63.7% to $2.98 in pre-market trading after declining around 7% on Monday.
• Nuburu, Inc. (NASDAQ:BURU) gained 52.1% to $0.6801 in pre-market trading after the company secured $65 million financing from Liqueous LP, to accelerate commercialization.
• GRI Bio, Inc. (NASDAQ:GRI) shares rose 47.3% to $0.4998 in pre-market trading. Ascendiant Capital analyst Edward Woo initiated coverage on GRI Bio with a Buy rating and announced a price target of $12.
• Virios Therapeutics, Inc. (NASDAQ:VIRI) shares gained 27% to $0.1750 in pre-market trading after dipping around 20% on Monday. Virios Therapeutics, Inc. and Wex Pharmaceuticals, Inc. announced business combination to form Dogwood Therapeutics, Inc.
• Oragenics, Inc. (NYSE:OGEN) shares surged 18.1% to $0.4680 in pre-market trading after dipping over 5% on Monday.
• Oruka Therapeutics, Inc. (NASDAQ:ORKA) shares jumped 11.8% to $29.09 in pre-market trading. HC Wainwright & Co. analyst Mitchell Kapoor, on Monday, initiated coverage on Oruka Therapeutics with a Buy rating and announced a price target of $45.
• Mama’s Creations, Inc. (NASDAQ:MAMA) gained 9.9% to $9.00 in pre-market trading.
• Lytus Technologies Holdings PTV. Ltd. (NASDAQ:LYT) shares gained 9.1% to $1.80 in pre-market trading after declining 4% on Monday.

Losers

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