Latest news for Compugen (NASDAQ:CGEN) Stock

Compugen Ltd is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive computational discovery capabilities to identify novel drug targets and new biological pathways to develop therapeutics in the field of cancer immunotherapy. Its immuno-oncology pipeline consists of four clinical-stage programs, targeting immune checkpoints the company discovered computationally, COM701, COM902, bapotulimab. The company's therapeutic pipeline of early-stage immuno-oncology programs consists of programs aiming to address various mechanisms of immune resistance, including myeloid targets.

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Alterity Therapeutics Limited - American Depositary Shares

ATHE

CGEN

TRDA

XAIR

Shares of Alterity Therapeutics (NASDAQ: ATHE) were up 7.8% on Jul 17 after the company announced positive interim data from the phase II ATH434-202 study evaluating its lead pipeline candidate ATH434 for treating patients with multiple system atrophy, a rare neurodegenerative disease.

Alterity Up on Interim Data From Advance MSA Study

ARQT

BIIB

LXEO

Shares of Lexeo Therapeutics (NASDAQ: LXEO) lost 26% on Monday after it reported positive interim data from two cohorts of the phase I/II SUNRISE-FA study evaluating LX2006, an investigational gene therapy for treating Friedreich ataxia (FA) cardiomyopathy.

Lexeo Down Despite Upbeat Rare Disease Gene Therapy Data

ALXO

ANVS

QURE

uniQure N.V. (NASDAQ: QURE) surged 76.5% on Jul 9 after it announced updated interim data, including up to 24 months of follow-up data, from 29 treated patients enrolled in the ongoing early to mid-stage studies of AMT-130 for Huntington&#39;s disease in the United States and EU.

UniQure Soars on New Huntington&#39;s Disease Study Data

Compugen Ltd

Compugen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGEN#NASDAQ">CGEN</a>) reported quarterly losses of $(0.02) per share which beat the analyst consensus estimate of $(0.07) by 71.43 percent. This is a 81.82 percent increase over losses of $(0.11) per share from the same period last year. The company reported quarterly sales of $6.70 million which beat the analyst consensus estimate of $2.49 million by 169.16 percent.

Compugen Q2 EPS $(0.02) Beats $(0.07) Estimate, Sales $6.70M

Compugen Announces FDA Has Cleared The IND For COM503 In Treatment Of Solid Tumors

Shares of Alterity Therapeutics (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/athe#NASDAQ">ATHE</a>) were up 7.8% on Jul 17 after the company announced positive interim data from the phase II ATH434-202 study evaluating its lead pipeline candidate ATH434 for treating patients with multiple system atrophy, a rare neurodegenerative disease. The study enrolled 10 participants with advanced MSA.
Per the press company, interim analysis results from the open-label ATH434-202 study included clinical and biomarker data from seven participants who were treated with ATH434 for six months and neuroimaging data from three participants who were treated with ATH434 for 12 months.
Data from the same showed that 43% of the participants displayed improvement on the Unified MSA Rating Scale Part I (UMSARS1), indicating reduced disability in activities of daily living following six months of treatment. Also, 29% of the participants had stable or improved neurological symptoms at the same time.
Patients who were treated with ATH434 had favorable clinical and biomarker outcomes, which underlined the potential of ATH434 to modify the course of MSA treatment.
Shares of Alterity have plunged 14.2% so far this year compared with the industry&#39;s decline of 1%.
Phase I studies conducted on ATH434 showed that the candidate is well tolerated and achieved brain levels that are comparable to efficacious levels seen in animal models of MSA.
Final 12-month data from the open-label ATH434-202 study is expected in the first half of 2025.
Alterity is currently evaluating ATH434 across two separate mid-stage studies. Apart from the ATH434-202 study, which evaluates ATH434 in more advanced MSA, the phase II ATH434-201 study is evaluating ATH434 in early-stage MSA.
An oral candidate, ATH434, is designed to inhibit the aggregation of pathological proteins implicated in neurodegeneration.
ATH434 has been granted orphan drug designation in treating MSA indications by the FDA and the European Medicines Agency.
<h3>Zacks Rank &amp; Stocks to Consider</h3>
Alterity currently carries a Zacks Rank #3 (Hold).
Some top-ranked stocks in the biotech sector are Entrada Therapeutics, Inc. (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/trda#NASDAQ">TRDA</a>), Compugen Ltd. (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/cgen#NASDAQ">CGEN</a>) and Beyond Air, Inc. (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/xair#NASDAQ">XAIR</a>), each sporting a Zacks Rank #1 (Strong Buy) at present.
In the past 60 days, estimates for Entrada Therapeutics&#39; 2024 loss per share have narrowed from 14 cents to 13 cents. Loss per share estimates for 2025 have narrowed from $3.44 to $3.21. Year to date, shares of TRDA have jumped 13.4%.
TRDA&#39;s earnings beat estimates in two of the trailing four quarters and missed the same on the remaining two occasions, the average surprise being 42.18%.
In the past 60 days, estimates for Compugen&#39;s 2024 earnings per share have improved from 2 cents to 5 cents, while loss per share estimates for 2025 have narrowed from 27 cents to 11 cents. Year to date, shares of CGEN have lost 6%.
CGEN&#39;s earnings beat estimates in three of the trailing four quarters and missed on the remaining occasion, the average surprise being 5.79%.
In the past 60 days, estimates for Beyond Air&#39;s 2024 loss per share have narrowed from 44 cents to 35 cents. Loss per share estimates for 2025 have narrowed from $1.45 to $1.01. Year to date, shares of XAIR have plunged 71.4%.
XAIR&#39;s earnings beat estimates in three of the trailing four quarters while missing the same on the other occasion, the average surprise being 8.77%.
<a href="https://www.zacks.com/stock/news/2304631/alterity-athe-up-on-interim-data-from-advance-msa-study?cid=CS-BENZ-FT-analyst_blog|company_news_medical_sector-2304631">To read this article on Zacks.com click here.</a>

Shares of Lexeo Therapeutics (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/lxeo#NASDAQ">LXEO</a>) lost 26% on Monday after it reported positive interim data from two cohorts of the phase I/II SUNRISE-FA study evaluating LX2006, an investigational gene therapy for treating Friedreich ataxia (FA) cardiomyopathy.
Data from the SUNRISE-FA study showed that treatment with LX2006 achieved a mean reduction in left ventricular mass index (LVMI) of 11.4% at 12 months and 18.3% at 18 months in participants with elevated LVMI at baseline. LVMI is an estimator of cardiac morbidity and mortality. Treatment with the therapy was also well-tolerated across all study participants, with no treatment-related serious adverse events.
The interim data also showed that treatment with LX2006 also showed improvement in other key measures of cardiac status, including left ventricular wall thickness (an early indicator of an inefficient heart) and troponin I (a biomarker of myocardial injury), in the majority of participants at 12 months.
Based on the above results, management sees a path for seeking the FDA&#39;s approval for LX2006 under the accelerated pathway.
Lexeo intends to report additional data at a future medical meeting later this year. Management is currently dosing patients in the third dose cohort of the SUNRISE-FA study, which is also enrolling study participants.
While Wall Street analysts were impressed with the results, some investors raised concerns about the data. They stated that the results were not enough to warrant accelerated approval from the FDA. The data also did not show that patients&#39; function improved after treatment with LX2006. This was likely the reason for the share price decline.
Year to date, Lexeo&#39;s shares have lost 3.0% compared with the industry&#39;s 3.6% fall.
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FA is an ultra-rare genetic, progressive, neurodegenerative movement disorder that affects nearly 5,000 diagnosed patients in the United States. FA cardiomyopathy is the most common cause of mortality in FA patients. Currently, there are no approved therapies for FA cardiomyopathy.
The only approved treatment for FA indication is Biogen&#39;s (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/biib#NASDAQ">BIIB</a>) Skyclarys, which is approved to treat FA in individuals aged 16 years and older. This drug, which was approved by the FDA last year, was added to Biogen&#39;s portfolio following the September 2023 acquisition of Reata Pharmaceuticals. However, the drug is effective in slowing neurological disease progression and does not impact the heart.
<h3>Zacks Rank &amp; Key Picks</h3>
Lexeo currently carries a Zacks Rank #3 (Hold). A couple of better-ranked stocks in the overall healthcare sector include Arcutis Biotherapeutics (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/arqt#NASDAQ">ARQT</a>) and Compugen (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/cgen#NASDAQ">CGEN</a>). While CGEN sports a Zacks Rank #1 (Strong Buy), ARQT carries a Zacks Rank #2 (Buy) at present.
In the past 60 days, estimates for Compugen&#39;s 2024 earnings per share have risen from 2 cents to 5 cents. During the same period, loss estimates per share for 2025 have improved from 27 cents to 11 cents. Year to date, CGEN&#39;s shares have lost 3.5%.
Earnings of Compugen beat estimates in three of the last four quarters while missing the mark on one occasion. CGEN delivered a four-quarter average earnings surprise of 5.79%.
In the past 60 days, estimates for Arcutis Biotherapeutics&#39; 2024 loss per share have narrowed from $2.22 to $1.60. During the same period, the loss estimates per share for 2025 have narrowed from $1.37 to $1.14. Year to date, shares of Arcutis have surged 233.4%.
Earnings of Arcutis Biotherapeutics beat estimates in three of the last four quarters while missing the mark on one occasion. Arcutis delivered a four-quarter average earnings surprise of 14.93%.
<a href="https://www.zacks.com/stock/news/2302828/lexeo-lxeo-down-despite-upbeat-rare-disease-gene-therapy-data?cid=CS-BENZ-FT-analyst_blog|company_news_medical_sector-2302828">To read this article on Zacks.com click here.</a>

uniQure N.V.&nbsp;(NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/qure#NASDAQ">QURE</a>) surged 76.5% on Jul 9 after it announced updated interim data, including up to 24 months of follow-up data, from 29 treated patients&nbsp;enrolled in the ongoing early to mid-stage studies of AMT-130 for Huntington&#39;s disease in the United States and EU. Results demonstrated a potential long-term, durable clinical benefit and reduction of a key marker of neurodegeneration upon treatment with the candidate.
AMT-130, a one-time administered investigational gene therapy, is being developed to treat Huntington&#39;s disease. Huntington&#39;s disease is a genetic disorder that causes the progressive breakdown of nerve cells in the brain, which leads to a decline in cognitive and physical abilities, often resulting in movement, thinking and psychiatric problems.
uniQure is simultaneously conducting two phase I/II studies of AMT-130, with 26 participants in the United States and 13 in the EU/UK to treat Huntington&#39;s disease. Among these, a total of 29 patients received either a low dose (12 patients) or a high dose (17 patients) of AMT-130, while 10 control patients underwent imitation surgery. As of Mar 31, 2024, follow-up data at 24 months were available for 21 patients, including 12 from the low-dose group and nine from the high-dose group.
Please note that uniQure, for the first time, performed a statistical analysis of clinical outcomes at 24 months for the 21 treated patients. This analysis, compared with an expanded, propensity-weighted external control group of 154 patients, developed in collaboration with the Cure Huntington&#39;s Disease Initiative. The control data was derived from the TRACK-HD, TRACK-ON and PREDICT-HD natural history studies.
Year to date, shares of QURE have lost 1.5% compared with the industry&#39;s 6.3% decline.
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Per the data readout from the phase I/II Huntington&#39;s disease studies, patients treated with the high dose of AMT-130 experienced a statistically significant, dose-dependent slowing in disease progression of 80%, as measured by cUHDRS after 24 months. For the low-dose group, a 30% slowing of disease progression, as measured by cUHDRS, was observed compared with the control group at month 24.
Please note that the cUHDRS has been demonstrated to be the most sensitive measurement of clinical progression in Huntington&#39;s disease patients.
Patients receiving the high dose of AMT-130 also showed near-baseline stability in motor and cognitive function throughout the 24 months of follow-up. Additionally, a statistically significant reduction of Neurofilament light chain (NfL)&nbsp;protein in cerebrospinal fluid (CSF) was observed in patients treated with AMT-130.
These patients had a mean reduction in CSF NfL of 11% compared with baseline at 24 months. Treatment with both dose strengths of AMT-130 resulted in mean CSF NfL levels below baseline at 24 months.
CSF NfL is an important biomarker of neurodegeneration and strongly associated with the clinical severity of Huntington&#39;s disease. An independent natural history study showed a 26% increase in CSF NfL at 24 months in patients with early manifest Huntington&#39;s disease.
Per the updated data, AMT-130 continues to be generally well-tolerated with a safety profile that is manageable at both doses. No new drug-related serious adverse events were reported.
We remind the investors that uniQure enjoys the FDA&#39;s Regenerative Medicine Advanced Therapy (RMAT) designation&nbsp;for AMT-130 to treat Huntington&#39;s disease.
The company is currently gearing up to hold an RMAT meeting with the FDA in the second half of 2024 to discuss these updated positive data seeking potential expedited clinical development pathways and accelerated approval for AMT-130.
In the second half of 2024, the company expects to complete enrolling patients in the third cohort of the&nbsp;U.S.&nbsp;phase I/II study exploring AMT-130 in combination with immunosuppression. Safety data from this cohort is anticipated in the first half of 2025.
Additionally, uniQure also shared its plan to present another interim analysis from the ongoing phase I/II studies of AMT-130 to treat Huntington&#39;s disease in mid-2025. The data from this interim analysis will include a 36-month comparison of treated patients to the propensity score-weighted external control.
Apart from AMT-130, uniQure&#39;s wholly-owned clinical pipeline comprises several other candidates that are currently undergoing early-stage development for the treatment of patients with refractory temporal lobe epilepsy, amyotrophic lateral sclerosis and Fabry disease. &nbsp;
Please note that the company also markets an internally developed gene therapy for the treatment of hemophilia B in the United States and EU under the brand name Hemgenix. The approvals in the U.S. and EU markets in 2022 and 2023, respectively, marked a significant milestone in the field of genomic medicine as it brought a new treatment approach for patients living with hemophilia.
<h3>Zacks Rank and Other Stocks to Consider</h3>
uniQure currently carries a Zacks Rank #2 (Buy).
Some other top-ranked stocks from the drug/biotech industryare ALX Oncology Holdings (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/alxo#NASDAQ">ALXO</a>), Annovis Bio (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/anvs#NYSE">ANVS</a>) and Compugen (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/cgen#NASDAQ">CGEN</a>), each carrying a Zacks Rank #2 at present.
In the past 30 days, the Zacks Consensus Estimate for ALX Oncology&#39;s 2024 loss per share has remained constant at $2.89. During the same period, the consensus estimate for 2025 loss per share has remained constant at $2.73. Year to date, shares of ALXO have plunged 57.3%.
ALX Oncology beat estimates in two of the trailing four quarters and missed twice, delivering an average negative surprise of 8.83%.
In the past 30 days, the Zacks Consensus Estimate for Annovis&#39; 2024 loss per share has remained constant at $2.46. During the same period, the consensus estimate for 2025 loss per share has remained constant at $1.95. Year to date, shares of ANVS have lost 22.1%.
ANVS beat estimates in three of the trailing four quarters and missed once, delivering an average negative surprise of 1.39%.
In the past 30 days, the Zacks Consensus Estimate for Compugen&#39;s 2024 earnings per share has remained constant at 5 cents. The consensus estimate for 2025 loss per share is currently pegged at 11 cents. Year to date, shares of CGEN have lost 11.1%.
CGEN&#39;s earnings beat estimates in three of the trailing four quarters and missed once, delivering an average surprise of 5.79%.
<a href="https://www.zacks.com/stock/news/2299274/uniqure-qure-soars-on-new-huntington-s-disease-study-data?cid=CS-BENZ-FT-analyst_blog|company_news_medical_sector-2299274">To read this article on Zacks.com click here.</a>

UniQure Soars on New Huntington's Disease Study Data

Merck (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/mrk#NYSE">MRK</a>) announced that the U.S. Centers for Disease Control and Prevention&#39;s (CDC) Advisory Committee on Immunization Practices (ACIP) has unanimously voted to recommend MRK&#39;s newly approved 21-valent&nbsp;pneumococcal conjugate vaccine (PCV) Capvaxive. The FDA approved Capvaxive earlier this month for the prevention of invasive pneumococcal disease and pneumococcal pneumonia in adults. Capvaxive became the first PCV specifically designed for adults to be approved by the FDA.
Capvaxive targets serotypes that account for approximately 84% of all invasive pneumococcal disease in older adults (50 years and older) in the United States, including eight serotypes not covered by currently licensed vaccines.
The ACIP recommends a single dose of Capvaxive for three distinct patient populations, the first being adults aged 65 years and older who have never received a pneumococcal conjugate vaccine or whose vaccination history is unknown. The second eligible patient population includes adults aged 19-64 years with certain underlying medical conditions or risk factors who have not previously received a pneumococcal conjugate vaccine or whose vaccination history is unknown.
The final patient population for whom ACIP recommends Merck&#39;s Capvaxive are adults aged 19 years and older who have begun their pneumococcal vaccine series with 13-valent PCV (PCV13) but have not received all the recommended pneumococcal 23-valent polysaccharide (PPSV23) vaccine doses.
Additionally, the ACIP advises that shared clinical decision-making should be applied for the use of a supplemental dose of Capvaxive for adults aged 65 years and older who have already completed their vaccine series with both PCV13 and PPSV23.
These new recommendations highlight Capvaxive&#39;s potential to enhance protection against pneumococcal disease in older adults and those with specific health conditions. However, these recommendations are provisional, which means they are not legally binding. These will only be official when the CDC reviews and finalizes the same.
Year to date, shares of MRK have jumped 19.1% compared with the industry&#39;s 21.9% growth.
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Capvaxive&#39;s approval was based on data from four phase III studies conducted across a range of adult populations. In the studies, Capvaxive demonstrated robust immune responses in both vaccine-na&iuml;ve and vaccine-experienced adult populations.
Merck also has a 15-valent PCV called Vaxneuvance (V114) in its vaccine portfolio that was approved in 2021. Vaxneuvance generated sales of $665 million in 2023, down 2% year over year.
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<h3>Merck &amp; Co., Inc. Price and Consensus</h3>
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Merck &amp; Co., Inc. price-consensus-chart | Merck &amp; Co., Inc. Quote
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<h3>Zacks Rank and Stocks to Consider</h3>
Merck currently carries a Zacks Rank #3 (Hold).
Some better-ranked stocks from the drug/biotech industry are ALX Oncology Holdings, Annovis Bio (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/anvs#NYSE">ANVS</a>) and Compugen (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/cgen#NASDAQ">CGEN</a>), each carrying a Zacks Rank #2 (Buy) at present.
In the past 30 days, the Zacks Consensus Estimate for ALX Oncology&#39;s 2024 loss per share has remained constant at $2.89. During the same period, the consensus estimate for 2025 loss per share has remained constant at $2.73. Year to date, shares of ALXO have plunged 60.8%.
ALX Oncology beat estimates in two of the trailing four quarters and missed twice, delivering an average negative surprise of 8.83%.
In the past 30 days, the Zacks Consensus Estimate for Annovis&#39; 2024 loss per share has remained constant at $2.46. During the same period, the consensus estimate for 2025 loss per share has remained constant at $1.95. Year to date, shares of ANVS have plunged 67.9%.
ANVS beat estimates in three of the trailing four quarters and missed once, delivering an average negative surprise of 1.39%.
In the past 30 days, the Zacks Consensus Estimate for Compugen&#39;s 2024 earnings per share has remained constant at 5 cents. The consensus estimate for 2025 loss per share is currently pegged at 11 cents. Year to date, shares of CGEN have lost 11.1%.
CGEN&#39;s earnings beat estimates in three of the trailing four quarters and missed once, delivering an average surprise of 5.79%.
<a href="https://www.zacks.com/stock/news/2294800/merck-s-mrk-new-pneumococcal-jab-capvaxive-gets-cdc-panel-vote?cid=CS-BENZ-FT-analyst_blog|company_news_medical_sector-2294800">To read this article on Zacks.com click here.</a>

Merck's New Pneumococcal Jab Capvaxive Gets CDC Panel Vote

Novo Nordisk&nbsp;(NYSE: <a class="ticker" href="https://www.benzinga.com/stock/nvo#NYSE">NVO</a>) lost 2.2% on Jun 26 after the company announced the failure of a late-stage study evaluating ocedurenone&nbsp;to treat patients with uncontrolled hypertension and advanced chronic kidney disease (CKD). Consequently, the company said that it will recognize an impairment loss of around DKK 5.7 billion related to the intangible assets in the second quarter of 2024.
Such recognition is expected to negatively impact operating profit growth by around 6 percentage points at the constant exchange rate (CER) in 2024. This adjustment revises the previously stated operating profit outlook of 22% to 30% growth at CER, as communicated in their financial report for the first quarter of 2024.
Novo Nordisk is slated to announce its financial results for the first six months of 2024 and update its financial outlook for 2024 on Aug 7, 2024.
Based on interim analysis, an independent data monitoring determined that the study did not meet its primary endpoint of reducing systolic blood pressure from baseline. This conclusion triggered Novo Nordisk&#39;s decision to halt the CLARION-CKD study.
Year to date, shares of NVO have jumped 38.9% compared with the industry&#39;s 23.1% growth.
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The investigational candidate, ocedurenone, is a novel third-generation non-steroidal mineralocorticoid receptor antagonist known for its distinct pharmacokinetic profile, featuring a prolonged half-life and strong affinity for the mineralocorticoid receptor.
Novo Nordisk acquired ocedurenone from KBP Biosciences in 2023. The phase III CLARION-CKD study, conducted by KBP Biosciences, aimed to assess ocedurenone&#39;s efficacy inmore than 600 enrolled patients with uncontrolled hypertension and advanced CKD, a condition for which effective treatments are critically needed. The study included a prespecified interim analysis after 12 weeks of treatment for all patients.
The decision to stop the trial underscores the challenges in developing effective therapies for complex conditions like advanced CKD and uncontrolled hypertension. The failure of ocedurenone brought into question the viability of the KBP Biosciences deal.
<h3>Zacks Rank and Stocks to Consider</h3>
Novo Nordisk currently carries a Zacks Rank #3 (Hold).
Some better-ranked stocks from the drug/biotech industry are ALX Oncology Holdings (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/alxo#NASDAQ">ALXO</a>), Annovis Bio (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/anvs#NYSE">ANVS</a>) and Compugen (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/cgen#NASDAQ">CGEN</a>), each carrying a Zacks Rank #2 (Buy) at present.
In the past 30 days, the Zacks Consensus Estimate for ALX Oncology&#39;s 2024 loss per share has remained constant at $2.89. During the same period, the consensus estimate for 2025 loss per share has remained constant at $2.73. Year to date, shares of ALXO have plunged 60.5%.
ALX Oncology beat estimates in two of the trailing four quarters and missed twice, delivering an average negative surprise of 8.83%.
In the past 30 days, the Zacks Consensus Estimate for Annovis&#39; 2024 loss per share has remained constant at $2.46. During the same period, the consensus estimate for 2025 loss per share has remained constant at $1.95. Year to date, shares of ANVS have plunged 69.4%.
ANVS beat estimates in three of the trailing four quarters and missed once, delivering an average negative surprise of 1.39%.
In the past 30 days, the Zacks Consensus Estimate for Compugen&#39;s 2024 earnings per share has remained constant at 5 cents. The consensus estimate for 2025 loss per share is currently pegged at 11 cents. Year to date, shares of CGEN have lost 11.6%.
CGEN&#39;s earnings beat estimates in three of the trailing four quarters and missed once, delivering an average surprise of 5.79%.
<a href="https://www.zacks.com/stock/news/2294455/novo-nordisk-s-nvo-hypertension-drug-study-fails-to-meet-goal?cid=CS-BENZ-FT-analyst_blog|company_news_medical_sector-2294455">To read this article on Zacks.com click here.</a>

Novo Nordisk's Hypertension Drug Study Fails to Meet Goal

Intellia Therapeutics&#39; (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/ntla#NASDAQ">NTLA</a>) shares gained 10% on Jun 3 after the company reported encouraging long-term data from the phase I portion of its early to mid-stage study evaluating NTLA-2002 for treating hereditary angioedema. Shares of NTLA continued to gain another 1.1% in the after-market hours.
NTLA-2002 is Intellia&#39;s investigational single-dose CRISPR/Cas9 gene-editing therapy, which is being developed as a one-time cure for HAE. It is a rare genetic condition that is marked by severe inflammatory attacks in various body organs and tissues, which can be painful and even life-threatening. Despite the current treatment options that require chronic administration for disease control, HAE attacks still occur.
NTLA-2002 aims to prevent HAE attacks by suppressing the plasma kallikrein activity. Per the management, the long-term data presented at a recent medical conference has bolstered the candidate&#39;s potential as a groundbreaking treatment for HAE as patients experienced durable elimination of their attacks in the ongoing phase I/II study.
Year to date, shares of Intellia have plunged 22.9% compared with the industry&#39;s 6.6% decline.
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A total of 10 patients are being treated in the phase I portion of the study with either of the three one-time doses (25 mg, 50 mg, or 75 mg) of NTLA-2002,administered via intravenous infusion. Eight of these patients experienced no attacks during the initial 16-week observation period. These patients have experienced ongoing attack-free durations of greater than 18 months.
After the last assessment of HAE attacks as of&nbsp;Feb 12, 2024, a 98% mean reduction in monthly attack rate and a 99% mean reduction in moderate to severe attacks were observed after a single dose of NTLA-2002 in the overall patient population. Robust and sustainable reduction in HAE attack rate was observed upon treatment with all dose levels.&nbsp;
Intellia reported that the longest attack-free interval for an individual patient post-infusion is more than 26 months and ongoing. Treatment with NTLA-2002 has also shown a persistent reduction in HAE attacksin patients with the most severe HAE symptoms.
In the phase I/II study&#39;s beginning, two patients had the highest historic monthly HAE attack rates (16.8 and 14.0 attacks per month, respectively). Both patients were attack-free by the end of the 16-week primary observation period and have remained free of attacks through the latest follow-up.&nbsp;
Furthermore, Intellia reported that the longest attack-free duration among these two patients is 23.5 months and ongoing.&nbsp;All patients who discontinued prophylaxis treatment after NTLA-2002 remain free of chronic prophylaxis treatment.
At the time of the latest follow-up, the mean reduction in plasma kallikrein levels from baseline upon treatment with NTLA-2002 was 60% (25 mg, 88 weeks), 88% (50 mg, 72 weeks) and 95% (75 mg, 88 weeks).
Per Intellia, all three doses of the gene therapy candidate were well-tolerated in the phase I portion of the early to mid-stage study and most adverse events were mild in severity.
The company plans to assess HAE attacks and plasma kallikrein protein levelsthrough the remainder of the two-year follow-up period.
It has completed enrollment in the phase II portion of the study that will further evaluate the 25 mg and 50 mg doses of NTLA-2002 for HAE, expecting to report top-line data soon. Intellia also anticipates initiating a pivotal phase III study of the candidate for the same indication in the second half of 2024, subject to regulatory feedback.
Please note that the company&#39;s clinical-stage pipeline comprises another gene-editing candidate, NTLA-2001, which is currently being evaluated in a late-stage study in partnership with Regeneron to treat transthyretin amyloidosis with cardiomyopathy.
<div class="chart_embed">
<h3>Intellia Therapeutics, Inc. Price and Consensus</h3>
<a href="https://www.zacks.com/stock/chart/NTLA/price-consensus-chart?icid=chart-NTLA-price-consensus-chart"><img alt="Intellia Therapeutics, Inc. Price and Consensus" src="https://staticx-tuner.zacks.com/images/charts/c8/1717507295.png" style="height:350px; width:600px" title="" /> </a>
Intellia Therapeutics, Inc. price-consensus-chart | Intellia Therapeutics, Inc. Quote
</div>
<h3>Zacks Rank and Stocks to Consider</h3>
Intellia currently carries a Zacks Rank #3 (Hold).
Some better-ranked stocks from the drug/biotech industry are ALX Oncology Holdings (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/alxo#NASDAQ">ALXO</a>), Annovis Bio (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/anvs#NYSE">ANVS</a>) and Compugen (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/cgen#NASDAQ">CGEN</a>), each carrying a Zacks Rank #2 (Buy) at present.
In the past 30 days, the Zacks Consensus Estimate for ALX Oncology&#39;s 2024 loss per share has narrowed from $3.33 to $2.89. During the same period, the consensus estimate for 2025 loss per share has narrowed from $2.85 to $2.73. Year to date, shares of ALXO have plunged 39.8%.
ALX Oncology beat estimates in two of the trailing four quarters and missed twice, delivering an average negative surprise of 8.83%.
In the past 30 days, the Zacks Consensus Estimate for Annovis&#39; 2024 loss per share has narrowed from $2.93 to $2.46. During the same period, the consensus estimate for 2025 loss per share has narrowed from $2.83 to $1.95. Year to date, shares of ANVS have plunged 63.5%.
ANVS beat estimates in three of the trailing four quarters and missed once, delivering an average negative surprise of 1.39%.
In the past 30 days, the Zacks Consensus Estimate for Compugen&#39;s 2024 earnings per share has increased from 2 cents to 5 cents. The consensus estimate for 2025 loss per share is currently pegged at 11 cents. Year to date, shares of CGEN have gained 10.6%.
CGEN&#39;s earnings beat estimates in three of the trailing four quarters and missed once, delivering an average surprise of 5.79%.
<a href="https://www.zacks.com/stock/news/2283508/intellia-ntla-up-on-upbeat-long-term-angioedema-study-data?cid=CS-BENZ-FT-analyst_blog|company_news_medical_sector-2283508">To read this article on Zacks.com click here.</a>

NTLA

Intellia Up on Upbeat Long-Term Angioedema Study Data

Compugen To Receive $5M Milestone Payment From AstraZeneca Following Dosing Of First Patient In Second Phase 3 Trial Of Rilvegostomig

Truist Securities analyst Asthika Goonewardene maintains Compugen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGEN#NASDAQ">CGEN</a>) with a Buy and lowers the price target from $5 to $4.

Price Target

Truist Securities Maintains Buy on Compugen, Lowers Price Target to $4

Guidance

Health Care

Compugen Expects Its Cash And Cash-related Balances Of $101.3M Together With A $30M Milestone Payment On COM503 IND Clearance Expected In 2024, Is Expected To Provide Cash Runway Into 2027

Compugen Q1 2024 GAAP EPS $(0.08) Beats $(0.11) Estimate, Sales $2.559M Miss $6.213M Estimate

David will join Compugen from Oramed Pharmaceuticals Inc., where he served as Chief Financial Officer.

Management

ORMP

Compugen Appoints David Silberman As Its New CFO Effective August 15, 2024, Taking Over From Alberto Sessa Who Will Depart On The Same Day

Compugen Reports Publication Of Paper In Cancer Immunology Research Demonstrating Therapeutic Potential Of COM503

Truist Securities analyst Asthika Goonewardene maintains Compugen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGEN#NASDAQ">CGEN</a>) with a Buy and raises the price target from $4 to $5.

Truist Securities Maintains Buy on Compugen, Raises Price Target to $5

WIIM

Compugen shares are trading lower after the company reported worse-than-expected Q4 EPS results.

Compugen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGEN#NASDAQ">CGEN</a>) reported quarterly earnings of $0.11 per share which missed the analyst consensus estimate of $0.23 by 52.17 percent. This is a 375 percent increase over losses of $(0.04) per share from the same period last year. The company reported quarterly sales of $33.46 million which beat the analyst consensus estimate of $20.00 million by 67.30 percent. This is a 346.12 percent increase over sales of $7.50 million the same period last year.

Compugen Q4 EPS $0.11 Misses $0.23 Estimate, Sales $33.46M Beat $20.00M Estimate

<h3>Companies Reporting Before The Bell</h3>
&bull; NIO (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/NIO#NYSE">NIO</a>) is estimated to report quarterly loss at $0.51 per share on revenue of $2.29 billion.
&bull; Target (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/TGT#NYSE">TGT</a>) is estimated to report quarterly earnings at $2.22 per share on revenue of $29.33 billion.
&bull; 2seventy bio (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TSVT#NASDAQ">TSVT</a>) is expected to report quarterly loss at $0.99 per share on revenue of $14.71 million.
&bull; CLPS (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CLPS#NASDAQ">CLPS</a>) is expected to report earnings for its first quarter.
&bull; Seres Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MCRB#NASDAQ">MCRB</a>) is projected to report quarterly loss at $0.50 per share on revenue of $350 thousand.
&bull; Vivid Seats (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SEAT#NASDAQ">SEAT</a>) is expected to report quarterly earnings at $0.06 per share on revenue of $183.67 million.
&bull; Nuwellis (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NUWE#NASDAQ">NUWE</a>) is projected to report quarterly loss at $1.39 per share on revenue of $2.55 million.
&bull; Consolidated Comms Hldgs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CNSL#NASDAQ">CNSL</a>) is likely to report quarterly loss at $0.36 per share on revenue of $276.94 million.
&bull; CECO Environmental (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CECO#NASDAQ">CECO</a>) is likely to report quarterly earnings at $0.24 per share on revenue of $146.61 million.
&bull; 908 Devices (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MASS#NASDAQ">MASS</a>) is expected to report quarterly loss at $0.26 per share on revenue of $14.16 million.
&bull; Neuronetics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/STIM#NASDAQ">STIM</a>) is projected to report quarterly loss at $0.26 per share on revenue of $19.85 million.
&bull; Broadwind (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BWEN#NASDAQ">BWEN</a>) is expected to report quarterly earnings at $0.00 per share on revenue of $50.15 million.
&bull; Global Business Travel (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/GBTG#NYSE">GBTG</a>) is projected to report quarterly loss at $0.03 per share on revenue of $541.17 million.
&bull; Riskified (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/RSKD#NYSE">RSKD</a>) is likely to report quarterly earnings at $0.03 per share on revenue of $84.02 million.
&bull; Angel Oak Mortgage REIT (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AOMR#NYSE">AOMR</a>) is expected to report quarterly earnings at $0.18 per share on revenue of $9.00 million.
&bull; L.B. Foster (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FSTR#NASDAQ">FSTR</a>) is expected to report quarterly earnings at $0.01 per share on revenue of $129.35 million.
&bull; Rand Capital (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RAND#NASDAQ">RAND</a>) is expected to report earnings for its fourth quarter.
&bull; Dave (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DAVE#NASDAQ">DAVE</a>) is likely to report earnings for its fourth quarter.
&bull; Sophia Genetics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SOPH#NASDAQ">SOPH</a>) is projected to report quarterly loss at $0.26 per share on revenue of $17.33 million.
&bull; First Watch Restaurant Gr (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FWRG#NASDAQ">FWRG</a>) is expected to report quarterly earnings at $0.04 per share on revenue of $237.53 million.
&bull; Compugen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGEN#NASDAQ">CGEN</a>) is likely to report quarterly earnings at $0.22 per share on revenue of $20.00 million.
&bull; SmartRent (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/SMRT#NYSE">SMRT</a>) is likely to report quarterly loss at $0.01 per share on revenue of $59.49 million.
&bull; Ferguson (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FERG#NYSE">FERG</a>) is estimated to report quarterly earnings at $1.85 per share on revenue of $6.77 billion.
&bull; Cipher Mining (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CIFR#NASDAQ">CIFR</a>) is estimated to report quarterly loss at $0.04 per share on revenue of $41.78 million.
&bull; Axogen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AXGN#NASDAQ">AXGN</a>) is likely to report quarterly loss at $0.10 per share on revenue of $41.65 million.
&bull; V2X (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/VVX#NYSE">VVX</a>) is expected to report quarterly earnings at $0.33 per share on revenue of $1.01 billion.
&bull; Wag Group (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PET#NASDAQ">PET</a>) is likely to report earnings for its fourth quarter.
&bull; Myers Indus (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MYE#NYSE">MYE</a>) is expected to report quarterly earnings at $0.26 per share on revenue of $196.19 million.
<h3>Companies Reporting After The Bell</h3>
&bull; Fabrinet (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FN#NYSE">FN</a>) is estimated to report quarterly earnings at $0.80 per share on revenue of $197.70 million.
&bull; Nordstrom (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/JWN#NYSE">JWN</a>) is estimated to report quarterly earnings at $0.88 per share on revenue of $4.39 billion.
&bull; BlackRock Cap Inv (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BKCC#NASDAQ">BKCC</a>) is likely to report quarterly earnings at $0.12 per share on revenue of $20.32 million.
&bull; Presto Automation (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PRST#NASDAQ">PRST</a>) is likely to report earnings for its fourth quarter.
&bull; Kingsway Financial Servs (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/KFS#NYSE">KFS</a>) is likely to report earnings for its fourth quarter.
&bull; Emergent BioSolutions (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/EBS#NYSE">EBS</a>) is expected to report quarterly loss at $0.19 per share on revenue of $293.53 million.
&bull; Cumberland (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CPIX#NASDAQ">CPIX</a>) is likely to report earnings for its fourth quarter.
&bull; TRACON Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TCON#NASDAQ">TCON</a>) is likely to report quarterly loss at $0.08 per share on revenue of $1.00 million.
&bull; Entravision Comms (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/EVC#NYSE">EVC</a>) is projected to report quarterly earnings at $0.07 per share on revenue of $308.47 million.
&bull; Bionano Genomics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BNGO#NASDAQ">BNGO</a>) is projected to report quarterly loss at $0.87 per share on revenue of $10.58 million.
&bull; Inspirato (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ISPO#NASDAQ">ISPO</a>) is likely to report quarterly loss at $3.66 per share on revenue of $73.50 million.
&bull; Marinus Pharma (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MRNS#NASDAQ">MRNS</a>) is expected to report quarterly loss at $0.62 per share on revenue of $8.01 million.
&bull; Allient (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ALNT#NASDAQ">ALNT</a>) is expected to report quarterly earnings at $0.32 per share on revenue of $132.56 million.
&bull; Bristow Group (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/VTOL#NYSE">VTOL</a>) is projected to report quarterly earnings at $0.54 per share on revenue of $329.20 million.
&bull; Greenlight Capital Re (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GLRE#NASDAQ">GLRE</a>) is estimated to report earnings for its fourth quarter.
&bull; Rigel Pharmaceuticals (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/RIGL#NASDAQ">RIGL</a>) is estimated to report quarterly loss at $0.03 per share on revenue of $34.10 million.
&bull; Plus Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PSTV#NASDAQ">PSTV</a>) is projected to report quarterly loss at $1.07 per share on revenue of $1.06 million.
&bull; Socket Mobile (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SCKT#NASDAQ">SCKT</a>) is estimated to report quarterly loss at $0.06 per share on revenue of $4.91 million.
&bull; Nyxoah (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NYXH#NASDAQ">NYXH</a>) is expected to report quarterly loss at $0.40 per share on revenue of $1.95 million.
&bull; Park-Ohio Hldgs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/PKOH#NASDAQ">PKOH</a>) is likely to report quarterly earnings at $0.55 per share on revenue of $386.45 million.
&bull; W&amp;T Offshore (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/WTI#NYSE">WTI</a>) is expected to report quarterly earnings at $0.01 per share on revenue of $138.42 million.
&bull; Cadre Hldgs (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CDRE#NYSE">CDRE</a>) is projected to report quarterly earnings at $0.18 per share on revenue of $121.79 million.
&bull; Semler Scientific (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/SMLR#NASDAQ">SMLR</a>) is expected to report quarterly earnings at $0.57 per share on revenue of $14.50 million.
&bull; Agiliti (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AGTI#NYSE">AGTI</a>) is projected to report quarterly earnings at $0.11 per share on revenue of $291.41 million.
&bull; Nuvei (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NVEI#NASDAQ">NVEI</a>) is projected to report quarterly earnings at $0.45 per share on revenue of $319.51 million.
&bull; Franco-Nevada (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/FNV#NYSE">FNV</a>) is estimated to report quarterly earnings at $0.84 per share on revenue of $283.00 million.
&bull; Mayville Engineering (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MEC#NYSE">MEC</a>) is projected to report quarterly earnings at $0.13 per share on revenue of $152.30 million.
&bull; Aquestive Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/AQST#NASDAQ">AQST</a>) is likely to report quarterly loss at $0.08 per share on revenue of $11.63 million.
&bull; Orthofix Medical (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/OFIX#NASDAQ">OFIX</a>) is expected to report earnings for its fourth quarter.
&bull; MeridianLink (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/MLNK#NYSE">MLNK</a>) is estimated to report quarterly loss at $0.13 per share on revenue of $74.86 million.
&bull; Ross Stores (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ROST#NASDAQ">ROST</a>) is likely to report earnings for its fourth quarter.
&bull; Cerus (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CERS#NASDAQ">CERS</a>) is expected to report quarterly loss at $0.02 per share on revenue of $49.27 million.
&bull; American Public Education (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/APEI#NASDAQ">APEI</a>) is projected to report quarterly earnings at $0.14 per share on revenue of $150.47 million.
&bull; Cricut (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CRCT#NASDAQ">CRCT</a>) is estimated to report quarterly earnings at $0.05 per share on revenue of $249.68 million.
&bull; Crexendo (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CXDO#NASDAQ">CXDO</a>) is projected to report quarterly earnings at $0.04 per share on revenue of $13.80 million.
&bull; Aeva Technologies (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AEVA#NYSE">AEVA</a>) is likely to report quarterly loss at $0.15 per share on revenue of $1.57 million.
&bull; LSB Industries (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/LXU#NYSE">LXU</a>) is estimated to report quarterly earnings at $0.04 per share on revenue of $127.21 million.
&bull; PlayAGS (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/AGS#NYSE">AGS</a>) is projected to report quarterly earnings at $0.03 per share on revenue of $92.57 million.
&bull; Full House Resorts (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FLL#NASDAQ">FLL</a>) is likely to report quarterly loss at $0.14 per share on revenue of $63.13 million.
&bull; CrowdStrike Holdings (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CRWD#NASDAQ">CRWD</a>) is expected to report quarterly earnings at $0.82 per share on revenue of $839.04 million.
&bull; HashiCorp (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/HCP#NASDAQ">HCP</a>) is expected to report quarterly earnings at $0.01 per share on revenue of $149.29 million.
&bull; Banco BBVA Argentina (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BBAR#NYSE">BBAR</a>) is estimated to report earnings for its fourth quarter.
&bull; NeuroPace (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NPCE#NASDAQ">NPCE</a>) is expected to report quarterly loss at $0.31 per share on revenue of $17.46 million.
&bull; Couchbase (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/BASE#NASDAQ">BASE</a>) is projected to report earnings for its fourth quarter.
&bull; Ooma (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/OOMA#NYSE">OOMA</a>) is likely to report quarterly earnings at $0.12 per share on revenue of $61.46 million.
&bull; ChargePoint Hldgs (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/CHPT#NYSE">CHPT</a>) is likely to report quarterly loss at $0.13 per share on revenue of $119.59 million.
&bull; ODDITY Tech (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/ODD#NASDAQ">ODD</a>) is expected to report earnings for its fourth quarter.
&bull; NewtekOne (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/NEWT#NASDAQ">NEWT</a>) is projected to report quarterly earnings at $0.58 per share on revenue of $63.35 million.
&bull; Box (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BOX#NYSE">BOX</a>) is expected to report quarterly earnings at $0.38 per share on revenue of $262.95 million.
&bull; Weyco Group (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/WEYS#NASDAQ">WEYS</a>) is projected to report earnings for its fourth quarter.
&bull; Alexandria Real Estate (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/ARE#NYSE">ARE</a>) is likely to report earnings for its fourth quarter.
This article was generated by Benzinga&#39;s automated content engine and reviewed by an editor.

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Earnings Scheduled For March 5, 2024

Compugen (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CGEN#NASDAQ">CGEN</a>) is set to give its latest quarterly earnings report on Tuesday, 2024-03-05. Here's what investors need to know before the announcement.
Analysts estimate that Compugen will report an earnings per share (EPS) of $0.22. 
Compugen bulls will hope to hear the company announce they've not only beaten that estimate, but also to provide positive guidance, or forecasted growth, for the next quarter.
New investors should note that it is sometimes not an earnings beat or miss that most affects the price of a stock, but the guidance (or forecast).
<h3>Historical Earnings Performance</h3>
Last quarter the company missed EPS by $0.02, which was followed by a 5.93% drop in the share price the next day.
Here's a look at Compugen's past performance and the resulting price change:

<table>
<thead>
<tr>
<th>Quarter</th>
<th>Q3 2023</th>
<th>Q2 2023</th>
<th>Q1 2023</th>
<th>Q4 2022</th>
</tr>
</thead>
<tbody>
<tr>
<td>EPS Estimate</td>
<td>-0.09</td>
<td>-0.13</td>
<td>-0.12</td>
<td>-0.14</td>
</tr>
<tr>
<td>EPS Actual</td>
<td>-0.11</td>
<td>-0.11</td>
<td>-0.11</td>
<td>-0.04</td>
</tr>
<tr>
<td>Price Change %</td>
<td>-6.0%</td>
<td>2.0%</td>
<td>-5.0%</td>
<td>4.0%</td>
</tr>
</tbody>
</table>

<img src="https://www.benzinga.com/files/images/story/2024/1709571707_0.png" alt="eps graph" />
<h3>Stock Performance</h3>
Shares of Compugen were trading at $2.64 as of March 01. Over the last 52-week period, shares are up 243.79%. Given that these returns are generally positive, long-term shareholders are likely bullish going into this earnings release. 
<a href="https://www.benzinga.com/quote/CGEN/earnings">To track all earnings releases for Compugen visit their earnings calendar on our site.</a>
This article was generated by Benzinga's automated content engine and reviewed by an editor.

Earnings Preview For Compugen

Earlier Compugen Announced It Regained Compliance With Nasdaq Minimum Bid Price Requirement

Compugen Q2 2024 Earnings Preview

Here is the next potential market catalyst

Compugen GAAP EPS of -$0.02, revenue of $6.7M

Compugen (CGEN) has released an update. Compugen Ltd. announced a solid Q2 2024 performance with FDA clearance for COM503 triggering a $30 million ...

Compugen's Strategic Milestones Boost Q2 2024 Outlook

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Compugen (NASDAQ:<a href="https://investorplace.com/stock-quotes/cgen-stock-quote/">CGEN</a>) just reported results for the second quarter of 2024.<ul><li>Compugen reported earnings per share of -2 cents. This was above the analyst estimate for EPS of -7 cents.</li><li>The company reported revenue of $6.70 million.</li><li>This was 169.16% better than the analyst estimate for revenue of $2.49 million.</li></ul><div>InvestorPlace Earnings is a project that leverages data from <a href="https://www.tradesmith.com">TradeSmith</a> to automate coverage of quarterly earnings reports. InvestorPlace Earnings distills key takeaways including earnings per share and revenue, as well as how a company stacks up to analyst estimates. These articles are published without human intervention, allowing us to inform our readers of the latest figures as quickly as possible. To report any concerns or inaccuracies, please contact us at <a href="mailto:editor@investorplace.com">editor@investorplace.com</a>.</div><h3>More From InvestorPlace</h3>
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									</ul>The post <a href="https://investorplace.com/earning-results/2024/08/cgen-stock-earnings-compugen-for-q2-of-2024/">CGEN Stock Earnings: Compugen Beats EPS, Beats Revenue for Q2 2024</a> appeared first on <a href="https://investorplace.com">InvestorPlace</a>.

CGEN Stock Earnings: Compugen Beats EPS, Beats Revenue for Q2 2024

Leerink Partners analyst Daina Graybosch has maintained their bullish stance on CGEN stock, giving a Buy rating on July 23. Daina Graybosch's ratin...

Compugen: Strong Buy on Promising Trials, Strategic Alliances, and Solid Financials

Compugen Ltd. (CGEN) Q2 2024 Earnings Call Transcript

In a report released today, Asthika Goonewardene from Truist Financial maintained a Buy rating on Compugen (CGEN – Research Report). The company's ...

Truist Financial Keeps Their Buy Rating on Compugen (CGEN)

Compugen (CGEN) has released an update. Compugen Ltd. successfully conducted its 2024 Annual General Meeting of Shareholders on September 12, 2024,...

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