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$104.91
1.491.44%
At close: Aug 7, 5:00 PM EST
$104.91
N/A
After Hours: Aug 7, 4:00 PM EST
Spyre Therapeutics Inc
SYRENASDAQ
Earnings: Q2 2026 Earnings were released on Tue Aug 4th, after the market close
Spyre Therapeutics Market Sentiment
Market sentiment signals for Spyre Therapeutics (SYRE): analyst consensus, short interest, options flow and insider activity.
Key Signals
Analyst Consensus▲ Buy
Short Interest▲ 15.5% short float
Options Flow▼ 55.00 P/C ratio
Insider Activity▼ Net Seller (30d)
Analyst Consensus
Buy
18 analysts
Options Flow (P/C)
55.00
More puts — Bearish
4 calls · 220 puts
Avg Consensus PT
$99
-5.3%
Highest Price Target
$135
+28.7%
Deutsche Bank
Lowest Price Target
$44
-58.1%
Guggenheim
Short Interest
15.5%
Declining — Bullish
Insider Activity (30d)
Net Seller
Short Interest — % of Float
Recent Analyst Actions
| Date | Firm | Analyst & Accuracy | Upside / Downside | PT Change | Action | Rating |
|---|---|---|---|---|---|---|
| Aug 5, 2026 | Wells Fargo | Yanan Zhu— | +9.6% | $90 → $115 | Maintained | Overweight |
| Aug 5, 2026 | Guggenheim | Yatin Suneja— | +23.9% | $115 → $130 | Maintained | Buy |
