$107.82
3.223.08%
At close: Aug 18, 5:00 PM EST
$107.82
N/A
After Hours: 4:00 PM EST
Spyre Therapeutics (SYRE) institutional and insider ownership, recent insider transactions and ownership breakdown.
Shares Outstanding
86.259M
Shares Float
80.543M
Insider Shares Owned
2.253M
Insider % Owned
2.6%
Institutional Shares Held
52.519M
Institutional % Held
59.6%
Ownership Breakdown
Net Insider Activity by Month
Purchases (90d)
0
Sales (90d)
6
$407.8M total
Net Activity
Net Selling
Net Value (90d)
-$407.8M
| Date | Insider | Title | Type | Shares | Price | Value |
|---|---|---|---|---|---|---|
| Aug 7, 2026 | Jeffrey Albers | DIRECTOR | SELL | 18.000K | $57.46 | $2.4M |
| Aug 3, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $55.03 | $608K |
| Aug 3, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $95.51 | $1.4M |
| Jul 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $51.12 | $549K |
| Jul 1, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $57.58 | $502K |
| Jul 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $87.69 | $1.3M |
| Jun 25, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $50.82 | $1.1M |
| Jun 23, 2026 | Fairmount Funds Management LLC, Fairmount Healthcare Fund II LP, Tomas Kiselak, Evan Peter Harwin | DIRECTOR | SELL | 4.018M | $85.31 | $399.7M |
| Jun 22, 2026 | THOMAS MICHAEL HENDERSON | DIRECTOR | SELL | 20.000K | $100.00 | $2.0M |
| Jun 3, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $51.23 | $396K |
| Jun 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $70.43 | $1.1M |
| Jun 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $42.78 | $424K |
| May 8, 2026 | THOMAS MICHAEL HENDERSON | DIRECTOR | SELL | 80.000K | $74.40 | $6.0M |
| May 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $42.94 | $711K |
| May 1, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $49.48 | $3.4M |
| May 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $71.37 | $1.1M |
| Apr 1, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $49.33 | $740K |
| Apr 1, 2026 | Sheldon Sloan | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $35.83 | $226K |
| Apr 1, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $31.92 | $261K |
| Mar 3, 2026 | Scott Burrows | CHIEF FINANCIAL OFFICER | SELL-OPTIONS | — | $27.57 | $65K |
| Mar 2, 2026 | Cameron Turtle | CHIEF EXECUTIVE OFFICER | SELL | 15.000K | $42.19 | $633K |
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