Septerna Ownership & Insider Activity

Septerna (SEPN) institutional and insider ownership, recent insider transactions and ownership breakdown.

Insiders own 2.8% of shares outstanding. Institutional investors hold 25.3%. Over the past 90 days, insiders made 1 sale worth $63.5M.

Shares Outstanding

46.677M

Shares Float

24.423M

Insider Shares Owned

1.297M

Insider % Owned

2.8%

Institutional Shares Held

11.801M

Institutional % Held

25.3%

Ownership Breakdown

Net Insider Activity by Month

Purchases (90d)

Sales (90d)

$63.5M total

Net Activity

Net Selling

Net Value (90d)

-$63.5M

Septerna Insider Transactions (Last 6 Months)

Date	Insider	Title	Type	Shares	Price	Value
Oct 15, 2026	Elizabeth Bhatt	PRESIDENT AND COO	SELL-OPTIONS	—	$22.11	$122K
Sep 1, 2026	Daniel Long	SVP, DRUG DISCOVERY	SELL-OPTIONS	—	$20.29	$117K
Aug 12, 2026	Third Rock Ventures V LP, Third Rock Ventures GP V LP, TRV GP V LLC, Third Rock Ventures VI LP, Third Rock Ventures GP VI LP, TRV GP VI LLC	—	s	147.200K	$50.27	$7.4M
Aug 12, 2026	RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah	DIRECTOR	SELL	1.493M	$42.50	$63.5M
Aug 11, 2026	Elizabeth Bhatt	PRESIDENT AND COO	SELL-OPTIONS	—	$24.89	$955K
Aug 3, 2026	Daniel Long	SVP, DRUG DISCOVERY	SELL-OPTIONS	—	$18.61	$106K
Jul 15, 2026	Elizabeth Bhatt	PRESIDENT AND COO	SELL-OPTIONS	—	$20.40	$109K
Jul 1, 2026	Daniel Long	SVP, DRUG DISCOVERY	SELL-OPTIONS	—	$18.56	$105K
Jun 29, 2026	Samira Shaikhly	CHIEF PEOPLE OFFICER	SELL-OPTIONS	—	$21.00	$62K
Jun 22, 2026	Daniel Long	SVP, DRUG DISCOVERY	SELL-OPTIONS	—	$20.47	$451K
Jun 12, 2026	Samira Shaikhly	CHIEF PEOPLE OFFICER	SELL-OPTIONS	—	$23.39	$146K
Jun 1, 2026	Samira Shaikhly	CHIEF PEOPLE OFFICER	SELL-OPTIONS	—	$15.40	$161K
May 26, 2026	Samira Shaikhly	CHIEF PEOPLE OFFICER	SELL-OPTIONS	—	$18.44	$274K