Ionis Pharmaceuticals Market Sentiment

Ionis Pharmaceuticals Inc

IONSNASDAQ

Trade with Public

$63.63

1.592.57%

Last update: Aug 25, 1:02 PM

Overview News Earnings Forecast Events Price Targets FinancialsSentimentOwnership Compare Options Stock Report

Ionis Pharmaceuticals Market Sentiment

Market sentiment signals for Ionis Pharmaceuticals (IONS): analyst consensus, short interest, options flow and insider activity.

Key Signals

Analyst Consensus▲ Buy

Short Interest▼ 17.1% short float

Options Flow▲ 0.23 P/C ratio

Insider Activity▲ Net Buyer (30d)

Analyst Consensus

Buy

28 analysts

Options Flow (P/C)

0.23

More calls — Bullish

1,064 calls · 244 puts

Avg Consensus PT

$87

+37.4%

Highest Price Target

$129

+102.7%

Leerink Partners

Lowest Price Target

$39

-38.7%

Redburn Atlantic

Short Interest

17.1%

Rising — Bearish

Insider Activity (30d)

Net Buyer

Short Interest — % of Float

Recent Analyst Actions

Date	Firm	Analyst & Accuracy	Upside / Downside	PT Change	Action	Rating
Aug 19, 2026	BMO Capital	David Lebowitz—	-5.7%	$60	Initiate	Outperform→Market Perform
Aug 3, 2026	JP Morgan	Jessica Fye—	+19.4%	$72 → $76	Maintained	Overweight
Jul 30, 2026	Wells Fargo	Yanan Zhu—	+49.3%	$100 → $95	Maintained	Overweight
Jul 30, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+80.7%	$125 → $115	Maintained	Buy
Jul 21, 2026	Guggenheim	Brad Canino—	+39.9%	$106 → $89	Maintained	Buy
Jul 16, 2026	Wolfe Research	Andy Chen—	—	—	Downgrade	Outperform→Peer Perform
Jul 13, 2026	RBC Capital	Luca Issi—	+33.6%	$100 → $85	Maintained	Outperform
Jul 10, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+96.4%	$130 → $125	Maintained	Buy
Jul 10, 2026	Morgan Stanley	Michael Ulz—	+72.9%	$130 → $110	Maintained	Overweight
Jul 10, 2026	Barclays	Eliana Merle—	+41.4%	$115 → $90	Maintained	Overweight
Jul 10, 2026	Canaccord Genuity	Gary Nachman—	+49.3%	$110 → $95	Maintained	Buy
Jul 10, 2026	Citigroup	Eric Joseph—	+57.1%	$115 → $100	Maintained	Buy
Jul 9, 2026	Jefferies	Akash Tewari—	+41.4%	$113 → $90	Maintained	Buy
Jul 9, 2026	Needham	Joseph Stringer—	+35.1%	$105 → $86	Maintained	Buy
Jun 25, 2026	Goldman Sachs	Salveen Richter—	+17.9%	$74 → $75	Maintained	Neutral
Jun 25, 2026	Leerink Partners	Mani Foroohar—	+102.7%	$122 → $129	Maintained	Outperform
Jun 25, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+104.3%	$125 → $130	Maintained	Buy
Jun 17, 2026	Leerink Partners	Mani Foroohar—	+91.7%	$114 → $122	Maintained	Outperform
Jun 15, 2026	TD Cowen	Yaron Werber—	+69.7%	$108 → $108	Maintained	Buy
Jun 1, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+96.4%	$125 → $125	Maintained	Buy
May 19, 2026	Citigroup	Eric Joseph—	+80.7%	$115	Initiate	Buy
Apr 30, 2026	RBC Capital	Luca Issi—	+57.1%	$95 → $100	Maintained	Outperform
Apr 30, 2026	Barclays	Eliana Merle—	+80.7%	$106 → $115	Maintained	Overweight
Apr 30, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+96.4%	$120 → $125	Maintained	Buy
Apr 23, 2026	TD Cowen	Yaron Werber—	+69.7%	$110 → $108	Maintained	Buy