Ionis Pharmaceuticals Market Sentiment

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Ionis Pharmaceuticals Inc

IONSNASDAQ

Trade with Public

$42.94

-1.18-2.67%

Last update: Oct 16, 4:00 PM

$43.88

-0.24-0.54%

Overview News Earnings Forecast Events Price Targets FinancialsSentimentOwnership Compare Options Stock Report

Ionis Pharmaceuticals Market Sentiment - Benzinga

Ionis Pharmaceuticals Market Sentiment

Market sentiment signals for Ionis Pharmaceuticals (IONS): analyst consensus, short interest, options flow and insider activity.

Key Signals

Analyst Consensus▲ Buy

Short Interest▼ 17.9% short float

Options Flow▼ 1.06 P/C ratio

Insider Activity— N/A

Analyst Consensus

Buy

28 analysts

Options Flow (P/C)

1.06

More puts — Bearish

789 calls · 837 puts

Avg Consensus PT

$86

+101.0%

Highest Price Target

$129

+200.4%

Leerink Partners

Lowest Price Target

$46

+7.1%

UBS

Short Interest

17.9%

Rising — Bearish

Insider Activity (30d)

—

Short Interest — % of Float

Recent Analyst Actions

Date	Firm	Analyst & Accuracy	Upside / Downside	PT Change	Action	Rating
Oct 15, 2026	UBS	Joon Lee—	+104.9%	$46 → $88	Upgrade	Neutral→Buy
Sep 24, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+132.9%	$100 → $100	Maintained	Buy
Sep 22, 2026	JP Morgan	Jessica Fye—	+63.0%	$76 → $70	Maintained	Overweight
Sep 15, 2026	Guggenheim	Debjit Chattopadhyay—	+86.3%	$89 → $80	Maintained	Buy
Sep 9, 2026	Barclays	Eliana Merle—	+98.0%	$90 → $85	Maintained	Overweight
Sep 8, 2026	Morgan Stanley	Michael Ulz—	+142.2%	$110 → $104	Maintained	Overweight
Sep 8, 2026	Goldman Sachs	Salveen Richter—	+30.4%	$69 → $56	Maintained	Neutral
Sep 8, 2026	BMO Capital	David Lebowitz—	+25.8%	$61 → $54	Maintained	Market Perform
Sep 8, 2026	Canaccord Genuity	Gary Nachman—	+98.0%	$95 → $85	Maintained	Buy
Sep 8, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+132.9%	$115 → $100	Maintained	Buy
Sep 4, 2026	Needham	Joseph Stringer—	+100.3%	$86 → $86	Maintained	Buy
Sep 4, 2026	BMO Capital	David Lebowitz—	+42.1%	$60 → $61	Maintained	Market Perform
Sep 4, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+167.8%	$115 → $115	Maintained	Buy
Aug 31, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+167.8%	$115 → $115	Maintained	Buy
Aug 19, 2026	BMO Capital	David Lebowitz—	+39.7%	$60	Initiate	Outperform→Market Perform
Aug 3, 2026	JP Morgan	Jessica Fye—	+77.0%	$72 → $76	Maintained	Overweight
Jul 30, 2026	Wells Fargo	Yanan Zhu—	+121.2%	$100 → $95	Maintained	Overweight
Jul 30, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+167.8%	$125 → $115	Maintained	Buy
Jul 21, 2026	Guggenheim	Brad Canino—	+107.3%	$106 → $89	Maintained	Buy
Jul 16, 2026	Wolfe Research	Andy Chen—	—	—	Downgrade	Outperform→Peer Perform
Jul 13, 2026	RBC Capital	Luca Issi—	+98.0%	$100 → $85	Maintained	Outperform
Jul 10, 2026	HC Wainwright & Co.	Mitchell S. Kapoor—	+191.1%	$130 → $125	Maintained	Buy
Jul 10, 2026	Morgan Stanley	Michael Ulz—	+156.2%	$130 → $110	Maintained	Overweight
Jul 10, 2026	Barclays	Eliana Merle—	+109.6%	$115 → $90	Maintained	Overweight
Jul 10, 2026	Canaccord Genuity	Gary Nachman—	+121.2%	$110 → $95	Maintained	Buy