JMP Views Positive Phase 3 Data Equivalent To 'Schizophrenia Blockbuster' For This Stock

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  • JMP Securities raised the price target on Karuna Therapeutics Inc KRTX from $175 to $190 with a Market Outperform rating. 
  • The analysts note Karuna as the top pick ahead of imminent Phase 3 results for KarXT in schizophrenia.
  • They note that results from the Phase 3 EMERGENT-2 trial are expected within weeks (estimated mid-July to mid-August), with high confidence levels (probability of success ~80%). 
  • "Looking ahead to KarXT's commercial potential, we believe that in addition to robust efficacy, differentiating attributes that can drive adoption are the novel mechanism of action and favorable safety/tolerability profile," JMP writes.
  • Also See: Amid Russia's Invasion On Ukraine, Karuna Therapeutics Withdraws Guidance On Late-Stage Schizophrenia Trial.
  • "We also believe that the opportunity for the candidate in additional indications, specifically ADP, remains underappreciated, and positive schizophrenia results should have broader positive read-through," it added.
  • The increased price target reflects higher U.S. peak penetration sales in schizophrenia (from $1.9 billion in 2028 to around $2.5 billion in 2030) and an increased probability of approval in Alzheimer's disease psychosis (ADP) (from 50% to 60%). 
  • Price Action: KRTX shares closed up 2.45% at $120.65 on Tuesday.
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