Gainers
- Peregrine Pharmaceuticals (NASDAQ: PPHM) rose 15.5 percent to $0.440 in pre-market trading after the company issued an update on oral presentation of top-line data from Phase III SUNRISE trial of bavituximab at the European Society for Medical Oncology (ESMO) 2016 Congress.
- Eleven Biotherapeutics Inc (NASDAQ: EBIO) rose 13.4 percent to $3.82 in pre-market trading. Eleven Biotherapeutics disclosed that it has acquired Viventia Bio.
- Clovis Oncology Inc (NASDAQ: CLVS) rose 9.2 percent to $38.05 in the pre-market trading. Clovis Oncology is a potential takeout target for a global pharma company, Credit Suisse said in a report. Credit Suisse upgraded the rating on the company from Neutral to Outperform, while raising the price target from $19 to $41.
- Conn's Inc (NASDAQ: CONN) rose 8.2 percent to $10.99 in pre-market trading. Stifel Nicolaus upgraded Conn's from Hold to Buy.
- Windtree Therapeutics Inc (NASDAQ: WINT) shares rose 8.1 percent to $2.93 in pre-market trading after surging 23.18 percent on Tuesday.
- Voltari Corp (NASDAQ: VLTC) shares rose 7.7 percent to $2.80 in pre-market trading after dropping 7.47 percent on Tuesday.
- Adobe Systems Incorporated (NASDAQ: ADBE) shares rose 5.3 percent to $105.91 in pre-market trading after the company posted better-than-expected results for its third quarter and issued a strong forecast for the current quarter.
- Ariad Pharmaceuticals, Inc. (NASDAQ: ARIA) shares rose 4.7 percent to $13.50 in pre-market trading after gaining 6.52 percent on Tuesday.
- FedEx Corporation (NYSE: FDX) rose 3.8 percent to $168.85 in pre-market trading as the company reported stronger-than-expected earnings for its first quarter on Tuesday.
- NuVasive, Inc. (NASDAQ: NUVA) rose 2.4 percent to $68.50 in pre-market trading. NuVasive will replace FEI Company (NASDAQ: FEIC) in the S&P MidCap 400.
- Microsoft Corporation (NASDAQ: MSFT) rose 1.2 percent to $57.50 in pre-market trading after the company announced a new $40 billion buyback plan and increased its quarterly dividend to $0.39 per share.
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Losers
- Mast Therapeutics Inc (NYSE: MSTX) shares fell 82.5 percent to $0.103 in pre-market trading after the company announced its phase-3 EPIC trial of vepoloxamer for the treatment of sickle cell disease patients experiencing vaso-occlusive crisis failed to meet its primary efficacy endpoint.
- CareDx Inc (NASDAQ: CDNA) fell 7.2 percent to $3.99 in pre-market trading after reporting a proposed public offering of common stock.
- Airgain Inc (NASDAQ: AIRG) fell 5.4 percent to $15.25 in pre-market trading. Airgain reported Q2 earnings of $0.15 per share on revenue of $9.9 million. Wunderlich downgraded Airgain from Buy to Hold.
- TASER International, Inc. (NASDAQ: TASR) shares fell 5.1 percent to $25.07 in pre-market trading as the company disclosed that its Axon unit has reported a purchase of 1,015 Axon Flex and Body 2 cameras by the Atlanta Police Department.
- CarMax, Inc (NYSE: KMX) shares fell 4.7 percent to $53.15 in pre-market trading following Q2 results. While its adjusted earnings came in line, revenue was below Street estimates.
- Willdan Group, Inc. (NASDAQ: WLDN) shares fell 4.7 percent to $16.69 in pre-market trading after gaining 0.11 percent on Tuesday.
- Aerie Pharmaceuticals Inc (NASDAQ: AERI) shares fell 4.6 percent to $36.80 in pre-market trading after rising 13.07 percent on Tuesday.
- Skechers USA Inc (NYSE: SKX) shares fell around 4 percent to $22.30 in pre-market trading. Morgan Stanley downgraded Skechers USA from Overweight to Equal-weight and lowered the price target from $41.00 to $25.00.
- KB Home (NYSE: KBH) shares fell 2.2 percent to $14.61 in pre-market trading. KB Home reported upbeat earnings for the third quarter, but sales missed expectations.
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