Septerna Analyst Price Targets

Wall Street analyst price targets and consensus rating for Septerna (SEPN).

Price Target Range — 8 Quarters

Analyst Consensus — 9 Analysts

1S.Buy

8Buy

Consensus RatingBuy# Analysts9Avg. Consensus PT$48Upside to Avg. PT+31.4%

Rating Trend — Last 9 Months

Recent Analyst Actions

Date	Firm	Analyst	Action	Rating Change	Price Target
Aug 19, 2026	JP Morgan	Tessa Romero	PT Raise	Overweight	$38→$48
Aug 13, 2026	Jones Trading	Catherine Novack	PT Raise	Buy	$43→$62
Aug 12, 2026	Wells Fargo	Derek Archila	PT Raise	Overweight	$48→$50
Aug 12, 2026	HC Wainwright & Co.	Raghuram Selvaraju	PT Raise	Buy	$40→$60
Aug 11, 2026	Guggenheim	Seamus Fernandez	PT Raise	Buy	$45→$51
Jul 1, 2026	Guggenheim	Seamus Fernandez	PT Cut	Buy	$52→$45
Jul 1, 2026	HC Wainwright & Co.	Raghuram Selvaraju	Maintained	Buy	$40
Jul 1, 2026	Truist Securities	Srikripa Devarakonda	PT Raise	Buy	$35→$43
Jun 8, 2026	Raymond James	Martin Auster	PT Raise	Strong Buy	$47→$53
May 13, 2026	HC Wainwright & Co.	Raghuram Selvaraju	Maintained	Buy	$40
Apr 14, 2026	HC Wainwright & Co.	Raghuram Selvaraju	Maintained	Buy	$40
Mar 24, 2026	JP Morgan	Tessa Romero	PT Raise	Overweight	$34→$38
Mar 11, 2026	Truist Securities	Srikripa Devarakonda	PT Raise	Buy	$34→$35
Mar 3, 2026	Wells Fargo	Derek Archila	PT Raise	Overweight	$28→$48
Mar 2, 2026	HC Wainwright & Co.	Raghuram Selvaraju	PT Raise	Buy	$35→$40
Jan 20, 2026	HC Wainwright & Co.	Raghuram Selvaraju	PT Raise	Buy	$30→$35
Dec 23, 2025	Jones Trading	Catherine Novack	Initiate	Buy	$43
Dec 19, 2025	Raymond James	Martin Auster	Initiate	Strong Buy	$38
Dec 15, 2025	Truist Securities	Srikripa Devarakonda	Initiate	Buy	$34
Nov 14, 2025	Wells Fargo	Derek Archila	Upgrade	Equal-Weight→Overweight	$18→$28