$6.33
-0.38-5.66%
At close: Dec 16, 4:00 PM EST
$6.33
N/A
After Hours: 4:02 PM EST

Short interest in Karyopharm Therapeutics Inc (NASDAQ:KPTI) decreased during the last reporting period, falling from 716.40K to 341.39K. This put 2.15% of the company's publicly available shares short.
Based on the recent average volume of 114.10K shares traded per day, it would take 2.99 day(s) for holders of this short interest to close out their positions without sending the stock sharply higher.
| Get Alert | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| KPTI | Karyopharm Therapeutics Inc. C | 11/28/2025 | 12/09/2025 | 2.15% | 15,861,175 | 341,393 | 114,102 | 2.99 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 11/14/2025 | 11/25/2025 | 4.52% | 15,861,175 | 716,400 | 97,669 | 7.33 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 10/31/2025 | 11/11/2025 | 4.09% | 15,861,175 | 648,449 | 137,661 | 4.71 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 10/15/2025 | 10/24/2025 | 9.07% | 15,861,175 | 1,438,931 | 433,727 | 3.32 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 09/30/2025 | 10/09/2025 | 26.22% | 8,605,514 | 2,256,786 | 114,902 | 19.64 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 09/15/2025 | 09/24/2025 | 25.61% | 8,605,514 | 2,204,008 | 73,044 | 30.17 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 08/29/2025 | 09/10/2025 | 25.35% | 8,605,514 | 2,181,633 | 139,544 | 15.63 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 08/15/2025 | 08/26/2025 | 24.92% | 8,605,514 | 2,144,496 | 270,977 | 7.91 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 07/31/2025 | 08/11/2025 | 24.80% | 8,574,140 | 2,126,753 | 150,954 | 14.09 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 07/15/2025 | 07/24/2025 | 24.12% | 8,574,140 | 2,068,242 | 279,105 | 7.41 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 06/30/2025 | 07/10/2025 | 23.67% | 8,574,140 | 2,029,574 | 38,051 | 53.34 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 06/13/2025 | 06/25/2025 | 23.59% | 8,574,140 | 2,022,280 | 79,783 | 25.35 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 05/30/2025 | 06/10/2025 | 24.19% | 8,574,140 | 2,073,899 | 72,710 | 28.52 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 05/15/2025 | 05/27/2025 | 24.36% | 8,574,140 | 2,088,644 | 93,880 | 22.25 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 04/30/2025 | 05/09/2025 | 23.27% | 8,504,413 | 1,978,892 | 88,581 | 22.34 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 04/15/2025 | 04/25/2025 | 21.57% | 8,504,413 | 1,834,115 | 144,542 | 12.69 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 03/31/2025 | 04/09/2025 | 15.69% | 8,352,035 | 1,310,201 | 177,123 | 7.4 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 03/14/2025 | 03/25/2025 | 12.80% | 8,352,035 | 1,068,912 | 138,705 | 7.71 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 02/28/2025 | 03/11/2025 | 12.66% | 8,352,035 | 1,057,156 | 160,615 | 6.58 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 02/14/2025 | 02/26/2025 | — | 8,352,035 | 20,790,198 | 833,590 | 24.94 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 01/31/2025 | 02/11/2025 | 16.08% | 125,231,236 | 20,136,096 | 659,763 | 30.52 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 01/15/2025 | 01/27/2025 | 15.81% | 125,231,236 | 19,796,924 | 880,520 | 22.48 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 12/31/2024 | 01/10/2025 | 15.54% | 125,231,236 | 19,461,323 | 1,317,914 | 14.77 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 12/13/2024 | 12/24/2024 | 15.80% | 125,231,236 | 19,792,052 | 1,200,908 | 16.48 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 11/29/2024 | 12/10/2024 | 15.40% | 122,898,339 | 18,922,751 | 413,126 | 45.8 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 11/15/2024 | 11/26/2024 | 15.41% | 122,898,339 | 18,934,223 | 849,154 | 22.3 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 10/31/2024 | 11/11/2024 | 14.40% | 122,898,339 | 17,693,166 | 951,782 | 18.59 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 10/15/2024 | 10/24/2024 | 14.41% | 122,267,514 | 17,614,095 | 876,938 | 20.09 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 09/30/2024 | 10/09/2024 | 15.21% | 122,267,514 | 18,601,001 | 761,208 | 24.44 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 09/13/2024 | 09/24/2024 | 14.66% | 122,267,514 | 17,926,868 | 520,433 | 34.45 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 08/30/2024 | 09/11/2024 | 15.14% | 122,267,514 | 18,515,873 | 425,981 | 43.47 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 07/31/2024 | 08/09/2024 | 15.03% | 122,267,514 | 18,373,169 | 951,197 | 19.32 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 07/15/2024 | 07/24/2024 | 15.46% | 122,199,565 | 18,891,867 | 1,172,420 | 16.11 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 06/28/2024 | 07/10/2024 | 17.71% | 122,199,565 | 21,644,093 | 2,532,324 | 8.55 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 06/14/2024 | 06/26/2024 | 17.50% | 122,199,565 | 21,382,722 | 1,222,546 | 17.49 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 05/31/2024 | 06/11/2024 | 16.49% | 122,199,565 | 20,146,797 | 1,300,245 | 15.49 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 05/15/2024 | 05/24/2024 | 15.23% | 115,294,096 | 17,559,879 | 1,344,210 | 13.06 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 04/30/2024 | 05/09/2024 | 14.89% | 115,294,096 | 17,167,388 | 1,267,737 | 13.54 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 04/15/2024 | 04/24/2024 | 20.66% | 114,049,569 | 23,560,996 | 1,009,948 | 23.33 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 03/28/2024 | 04/09/2024 | 20.29% | 113,103,855 | 22,947,206 | 906,964 | 25.3 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 03/15/2024 | 03/26/2024 | 20.45% | 113,103,855 | 23,131,558 | 1,462,387 | 15.82 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 02/29/2024 | 03/11/2024 | 20.72% | 113,103,855 | 23,438,591 | 1,705,214 | 13.75 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 02/15/2024 | 02/27/2024 | 20.81% | 112,570,763 | 23,429,296 | 4,129,484 | 5.67 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 01/31/2024 | 02/09/2024 | 16.79% | 112,570,763 | 18,897,827 | 952,361 | 19.84 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 01/12/2024 | 01/24/2024 | 16.59% | 112,570,763 | 18,678,745 | 1,171,374 | 15.95 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 12/29/2023 | 01/10/2024 | 15.94% | 112,570,763 | 17,946,993 | 1,562,944 | 11.48 | Get Alert |
| KPTI | Karyopharm Therapeutics Inc. C | 12/15/2023 | 12/27/2023 | 15.76% | 112,570,763 | 17,742,564 | 1,409,206 | 12.59 | Get Alert |
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