Bristol Myers' Breyanzi Immunotherapy Approved In Europe For Lymphoma Indications

The European Commission (EC) has approved Bristol Myers Squibb Co's BMY Breyanzi (lisocabtagene maraleucel; liso-cel) in relapsed or refractory lymphoma settings.

  • The approval for CD19-directed chimeric antigen receptor (CAR) T cell immunotherapy covers diffuse large B-cell lymphoma (DLBCL), primary mediastinal large B-cell lymphoma (PMBCL), and follicular lymphoma grade 3B (FL3B) after two or more lines of systemic therapy. 
  • Breyanzi is delivered as a personalized treatment via a single infusion. 
  • Related: Bristol Myers Squibb Scores Three Back To Back European Approvals For Opdivo In Esophageal, Urothelial Cancer.
  • The European approval is based on results from the TRANSCEND NHL 001 study in which 73% of patients achieved a response, including 53% who had minimal or no detectable lymphoma remaining following treatment.
  • The median duration of response was 20.2 months in all responders, and for patients who achieved a CR, the median duration of response was 26.1 months.
  • Price Action: BMY shares are up 1.12% at $74.61 during the market session on the last check Tuesday.

Posted In: BriefsEuropean Medicines AgencyBiotechNewsHealth CareGeneral

Ad Disclosure: The rate information is obtained by Bankrate from the listed institutions. Bankrate cannot guaranty the accuracy or availability of any rates shown above. Institutions may have different rates on their own websites than those posted on Bankrate.com. The listings that appear on this page are from companies from which this website receives compensation, which may impact how, where, and in what order products appear. This table does not include all companies or all available products.

All rates are subject to change without notice and may vary depending on location. These quotes are from banks, thrifts, and credit unions, some of whom have paid for a link to their own Web site where you can find additional information. Those with a paid link are our Advertisers. Those without a paid link are listings we obtain to improve the consumer shopping experience and are not Advertisers. To receive the Bankrate.com rate from an Advertiser, please identify yourself as a Bankrate customer. Bank and thrift deposits are insured by the Federal Deposit Insurance Corp. Credit union deposits are insured by the National Credit Union Administration.

Consumer Satisfaction: Bankrate attempts to verify the accuracy and availability of its Advertisers' terms through its quality assurance process and requires Advertisers to agree to our Terms and Conditions and to adhere to our Quality Control Program. If you believe that you have received an inaccurate quote or are otherwise not satisfied with the services provided to you by the institution you choose, please click here.

Rate collection and criteria: Click here for more information on rate collection and criteria.