Aldeyra Stock Trading Higher On FDA Orphan Drug Tag For Primary Vitreoretinal Lymphoma Candidate

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  • The FDA has granted Orphan Drug Designation to Aldeyra Therapeutics Inc's ALDX ADX-2191 (methotrexate for intravitreal injection) for primary vitreoretinal lymphoma (PVRL). 
  • PVRL is a rare ocular lymphoid malignancy consisting of a subset of primary central system lymphoma (PCNSL) and the most common type of intraocular lymphoma. 
  • ADX-2191 is designed to inhibit dihydrofolate reductase, an enzyme involved in cellular replication and activation. 
  • Methotrexate is the most commonly used intravitreal medication for the treatment of PVRL. 
  • Price Action: ALDX shares are up 7.18% at $9.85 during the premarket session on the last check Tuesday.
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Posted In: BiotechNewsHealth CareSmall CapFDAGeneralBriefsOrphan Drug Designation
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