Eloxx Pharma Sees Data Readout From First Four Arms Of Cystic Fibrosis Study By End Of 2021

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  • Eloxx Pharmaceuticals Inc ELOX provided an enrollment update for the ongoing Phase 2 trial of ELX-02 to treat cystic fibrosis (CF) in patients with at least one G542X allele. 
  • Based on enrollment to date, Eloxx expects to present data from the first four treatment arms in Q4 of 2021.
  • As of the end of June 2021, Eloxx has enrolled a sufficient number of patients to assess the biological activity of ELX-02. 
  • ELX-02 is currently in Phase 2 clinical trials in CF patients affected by nonsense mutations in the CFTR (CF transmembrane conductance regulator) gene.
  • Recently, a fifth treatment arm was added to the program to evaluate the safety of ELX-02 in combination with Vertex Pharmaceuticals Incorporated's VRTX Kalydeco (ivacaftor), an FDA-approved CFTR potentiator for cystic fibrosis in patients with at least one mutation in their CF gene amenable to ivacaftor.
  • The Cystic Fibrosis Foundation partially funds the program.
  • The U.S. Food and Drug Administration has granted orphan drug designation for ELX-02 for the treatment of CF.
  • Price Action: ELOX shares are up 2.6% at $1.98 during the premarket session on the last check Wednesday.
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Posted In: BiotechNewsPenny StocksHealth CareGeneralBriefsCystic Fibrosis
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