Techno Horizon (OTC:THHCF) Stock, Quote.Headers.trade-ideas

Techno Horizon Co Ltd is a Japan-based company engaged in optical business and electronic business. The company manufactures and sells optical, electrical, medical, and precision equipment; develops, manufactures, and sells information and communication equipment, FA related equipment, and other electronic devices; and produces and sells various optical lenses and plastic moulded products, as well as provides system integration services.

TECHNO HORIZON CO LTD by Techno Horizon Co Ltd.

Techno Horizon Co Ltd

The Federal Reserve has initiated its long-anticipated easing cycle, potentially setting the stage for a <a href="https://www.benzinga.com/markets/cryptocurrency/24/09/40938429/raoul-pals-chief-crypto-analyst-says-the-bull-market-is-back-when-this-indicator-hits-45-i">bullish trend in risk assets</a>, including Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) and other cryptocurrencies, according to industry experts.
What Happened: Economist and crypto analyst Alex Krüger took to his X account to <a href="https://x.com/krugermacro/status/1836621688877773090">highlight</a> the Fed&#8217;s decision to implement a 50-basis point cut while projecting an additional 50 basis points of cuts for 2024. 
This balanced approach, Krüger suggests, has struck a &#8220;sweet spot&#8221; by addressing concerns about the Fed falling behind the curve while simultaneously demonstrating control rather than reactionary measures.
For cryptocurrency enthusiasts, Krüger sees a bullish outlook for Bitcoin, though he cautions that its trajectory may be heavily influenced by the upcoming U.S. election results. 
He even suggested a bold strategy for altcoins: &#8220;For altcoins, go max long early in Election Night if Trump is coming up ahead in the counts. That&#8217;s my plan.&#8221;
Krüger emphasized the robust state of the U.S. economy, a factor he considers crucial for risk assets. He pointed out a historical trend: "Historically when the Fed begins its easing cycle with no recession, equities have rallied 10% in six months, while if the Fed begins the cycle in a recession, equities have fallen by 12%.&#8221;
<figure class="wp-block-image size-full"><img loading="lazy" decoding="async" width="300" height="250" src="https://editorial-assets.benzinga.com/wp-content/uploads/2024/03/29155259/905735A6-57D3-4874-9AA1-75D037842DB3-2.gif" alt="Benzinga Future of Digital Assets conference" class="wp-image-270548" /></figure>
Also Read: <a href="https://www.benzinga.com/analyst-ratings/analyst-color/24/09/40934438/analyst-predicts-energized-crypto-market-after-feds-decision-says-bitcoin-ethereum-">Analyst Predicts Energized Crypto Market After Fed&#8217;s Decision: Says Bitcoin, Ethereum, And DeFi Set To Rally Amid Anticipation Of Further Rate Cuts: &#8216;The Bull Market Has Started&#8217;</a>
Why It Matters: Economic strength was echoed in Fed Chair Jerome Powell's statement: "I don&#8217;t see anything in the economy that suggests the likelihood of a downturn is elevated. You see growth at a solid rate, you see inflation coming down, you see a labor market that&#8217;s still at very solid levels."
However, Krüger also tempered expectations, noting that U.S. equities are not cheap and that a return to a real negative rates environment is unlikely in the near future. He observed a significant divergence between market expectations and Fed projections for 2025, with the market pricing in a 25% probability of a hard landing.
In conclusion, Krüger&#8217;s analysis suggests that while the Fed&#8217;s easing cycle could boost risk assets, including cryptocurrencies, investors should remain vigilant of economic indicators and political developments that could shape market trends in the coming months.
What&#8217;s Next: The influence of&nbsp;<a href="https://www.benzinga.com/money/is-bitcoin-a-good-investment" target="_blank" rel="noreferrer noopener">Bitcoin as an institutional asset class</a>&nbsp;is expected to be thoroughly explored at Benzinga&#8217;s upcoming&nbsp;<a href="https://www.benzinga.com/events/digital-assets/agenda/" target="_blank" rel="noreferrer noopener">Future of Digital Assets</a>&nbsp;event on Nov. 19.
Read Next:
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<li><a href="https://www.benzinga.com/markets/cryptocurrency/24/09/40884546/91-chance-local-top-is-in-says-trader-ahead-of-pivotal-rate-cut-decision">&#8216;91% Chance Local Top Is In,&#8217; Says Trader Ahead Of Pivotal Rate Cut Decision</a></li>
</ul>
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What Does The Fed's Interest Rate Cut Mean For Bitcoin? 50 Bps Cut Is The 'Sweet Spot,' Says Macro Analyst

Chardan Capital analyst Geulah Livshits maintains 4D Molecular Therapeutics (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/FDMT#NASDAQ">FDMT</a>) with a Buy and raises the price target from $38 to $39.

Price Target

Analyst Ratings

FDMT

Chardan Capital Maintains Buy on 4D Molecular Therapeutics, Raises Price Target to $39

Verint Systems Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/VRNT#NASDAQ">VRNT</a>) shares are in the spotlight Thursday after The Bear Cave released a bearish report on <a href="https://www.benzinga.com/quote/VRNT" target="_blank" rel="noreferrer noopener">the contact center company</a>.
What To Know: Short-selling firm The Bear Cave has customer experience (CX) automation company Verint Systems in its crosshairs. The short seller published a report Thursday morning titled, &#8220;Problems at Verint Systems (VRNT),&#8221; arguing that the company is likely to be disrupted by <a href="http://benzinga.com/topic/ai">AI</a> advancement.
&#8220;Verint's management insists Verint will be an AI beneficiary as customers use Verint's AI-powered bots to improve their call centers. The Bear Cave sees things differently,&#8221; the short seller said.
Benzinga has reached out to Verint Systems for comment on the report.
The Bear Cave believes AI is going to negatively impact Verint as AI-powered competitors take share from its automated bot offerings and AI agents largely replace human agents over the coming years. The short seller believes Verint will &#8220;suffer significantly&#8221; as call centers transition away from humans. 
The Bear Cave also highlighted a pair of interviews from last month in which a former sales director for Verint acknowledged that competitors have adopted AI faster than Verint, and that the company may get left behind as it continues to focus on bots. The former sales director noted that it&#8217;s not clear if Verint will still be around in another 10 or 15 years, given the amount of AI-specific startups coming into the space, according to the short seller.
Check This Out: <a href="https://www.benzinga.com/top-stories/24/09/40937593/oracle-cloudworld-highlights-ai-driven-tech-services-but-revenue-growth-requires-patience-analyst">Oracle CloudWorld Highlights &#8216;AI-Driven Tech Services,&#8217; But Revenue Growth Requires Patience: Analyst</a>
The Bear Cave highlighted some of the increasing competition including from Alphabet Inc&#8217;s (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOG#NASDAQ">GOOG</a>)(NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/GOOGL#NASDAQ">GOOGL</a>) Google Dialogflow, International Business Machines Corp (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/IBM#NYSE">IBM</a>) and several startups like Yellow AI and Observe AI, which are aggressively moving into AI automation for call centers.
The firm also pointed to a recent <a href="https://www.benzinga.com/pressreleases/24/09/b40922898/t-mobile-and-openai-join-forces-to-revolutionize-the-customer-experience-with-first-ever-intent-dr">press release</a> from T-Mobile US Inc (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/TMUS#NASDAQ">TMUS</a>), announcing a partnership with OpenAI that aims to revolutionize the customer experience. The company expects the partnership to help automate tasks that would normally require a store visit or call to a customer service agent.
The short seller noted AI headwinds may be starting to show up in the company&#8217;s numbers. Last quarter, Verint <a href="https://www.benzinga.com/news/earnings/24/09/40737739/these-analysts-cut-their-forecasts-on-verint-systems-following-downbeat-q2-results">missed analyst estimates</a> on the top and bottom lines and issued soft guidance for the full year.
&#8220;The future is not bots, the future is not human agents, and the future is certainly not Verint,&#8221; the short seller said.
VRNT Price Action: Verint shares were up 0.67% at $26.38 at the time of publication Thursday, according to <a href="http://pro.benzinga.com">Benzinga Pro</a>.
Read Next:
<ul>
<li><a href="https://www.benzinga.com/news/24/09/40909973/blackrock-microsoft-others-team-up-for-30b-artificial-intelligence-fund-help-us-fuel-ai-innovation-a">BlackRock, Microsoft, Others Team Up For $30B Artificial Intelligence Fund: Help US Fuel &#8216;AI Innovation And Economic Growth&#8217;</a></li>
</ul>
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GOOG

GOOGL

TMUS

VRNT

Short Seller Targets Verint Systems Stock As AI Threat Emerges: 'The Future Is Certainly Not Verint'

Coinbase Global, Inc. (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/COIN#NASDAQ">COIN</a>) shares are trading higher Thursday as investors digest the first interest rate cut from the <a href="https://www.benzinga.com/news/earnings/24/09/40934972/wall-street-primed-for-relief-rally-as-traders-eye-jobless-claims-fedex-earnings-after-feds-50-basi">Federal Reserve in four years.</a>
The Details:
The Federal Reserve announced a 50 basis point (bps) cut Wednesday, bringing the federal funds rate down to a range of 4.75% to 5% and increasing the appeal of risk assets like stocks and cryptocurrencies.
Cryptocurrencies are rising with the broad market rally Thursday following Wednesday's rate cut. Bitcoin (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/btc/usd">BTC</a>) is trading above the $63,000 level and Ethereum (CRYPTO: <a class="ticker" href="https://www.benzinga.com/quote/eth/usd">ETH</a>) is up 2.17% over the past 24 hours. Both cryptocurrencies saw <a href="https://www.benzinga.com/markets/cryptocurrency/24/09/40926729/bitcoin-spikes-above-61-000-as-fed-implements-50-bps-rate-cut">increased trading</a> following the Federal Reserve&#8217;s surprise decision, which exceeded the anticipated 25 basis point cut.
Read Next: <a href="https://www.benzinga.com/fintech/24/09/40928342/what-happened-with-sofi-stock-today">What Happened With SoFi Stock Today?</a>
"These markets should benefit from the formalization of the Fed&#8217;s dovish shift. Our long-term investment thesis for Bitcoin remains intact, and regardless of the near-term direction of monetary policy, BTC is well-positioned for growth as institutional adoption continues to gain momentum," Hashdex&#8217;s CIO Samir Kerbage wrote in a note sent to Benzinga.&nbsp;
Coinbase shares are climbing on above-average volume Thursday, though the stock is trading well-below its 50-day moving average of $201.46, according to data from <a href="https://pro.benzinga.com/?gspk=YWRhbWVja2VydDUzMzY&amp;gsxid=zBMR4PKmcgBw">Benzinga Pro</a>.&nbsp;&nbsp;&nbsp;
<h3 class="wp-block-heading">Will COIN Stock Go Up?</h3>
When trying to assess whether or not Coinbase Global will trade higher from current levels, it's a good idea to take a look at analyst forecasts. 
Wall Street analysts have an average 12-month price target of $257.25 on Coinbase. The Street high target is currently at $345 and the Street low target is $169. Of all the analysts covering Coinbase, 7 have positive ratings, 3 have neutral ratings and 2 have negative ratings.
In the last month, one analyst has adjusted price targets. Here's a look at recent price target changes <a href="https://www.benzinga.com/quote/COIN/analyst-ratings">[Analyst Ratings]</a>. Benzinga also tracks Wall Street's most accurate analysts. Check out how analysts covering Coinbase Global have performed in recent history. 
Stocks don't move in a straight line. The average stock market return is approximately 10% per year. Coinbase is 10.56% up year-to-date. The average analyst price target suggests the stock could have further upside ahead.
For a broad overview of everything you need to know about Coinbase Global, visit <a href="https://www.benzinga.com/quote/COIN">here</a>. If you want to go above and beyond, there's no better tool to help you do just that than <a href="https://pro.benzinga.com/">Benzinga Pro</a>. Start your free trial today.
COIN Price Action: According to <a href="https://pro.benzinga.com/?gspk=YWRhbWVja2VydDUzMzY&amp;gsxid=zBMR4PKmcgBw">Benzinga Pro</a>, Coinbase Global shares are up 7.11% at $174.21 at the time of publication Thursday. 
Read Also:
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<li><a href="https://www.benzinga.com/news/24/09/40923038/whats-going-on-with-carnival-stock">What&#8217;s Going On With Carnival Stock?</a></li>
</ul>
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COIN

What's Going On With Coinbase Stock?

WIIM

MUSA

Murphy USA shares are trading lower after JP Morgan downgraded the stock from Neutral to Underweight but raised its price target from $415 to $435.

Nokia Corporation (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/nok#NYSE">NOK</a>) recently inked an agreement with iSAT Africa for an undisclosed amount to enhance broadband connectivity across rural areas in Liberia. The three-year deal spanning more than 200 sites in the West African country aims to bridge the digital divide by providing a reliable, affordable and easily accessible network to underserved rural communities.
<h2>How NOK Likely Secured the Deal</h2>
Nokia is well-positioned for the ongoing technology cycle, given the strength of its end-to-end portfolio. Its installed base of high-capacity AirScale products, which enables customers to upgrade to 5G quickly, is growing fast. It is driving the transition of global enterprises into smart virtual networks by creating a single network for all services, converging mobile and fixed broadband, IP routing and optical networks with the software and services to manage them. Leveraging state-of-the-art technology, it is transforming the way people and things communicate and connect.
The company aims to create new business and licensing opportunities in the consumer ecosystem. It facilitates customers to move away from an economy-of-scale network operating model to demand-driven operations by offering easy programmability and flexible automation required to support dynamic operations, reduce complexity and improve efficiency. It seeks to expand its business into targeted, high-growth and high-margin vertical markets to address growth opportunities beyond its traditional primary markets.
<h2>What This Collaboration Brings on the Table</h2>
Nokia&#39;s partnership with this integrated communications services provider that specializes in broadcasting &amp; rural connectivity in Africa and the Middle East will seek to drive socio-economic development in the remote areas of Liberia. Per the deal, Nokia will deploy its AirScale radio portfolio along with MantaRay Network Management solutions for effective monitoring and management capabilities to address critical challenges such as limited coverage and the wide digital divide in rural regions.
<h2>Will NOK Stock Benefit?</h2>
Nokia has emerged as one of the leading players in the development of advanced 5G technology and is at the forefront of extending 5G use cases in various industries. It has laid a strong foundation of innovation through substantial infrastructure investments. This has led to the establishment of an impressive portfolio comprising approximately 20,000 patent families, including more than 6,000 patent families that are deemed crucial to 5G technology.
The collaboration with iSAT Africa is likely to propel the stock on incremental revenue generation and inducement of similar deals from other carriers in the future. The agreement is also expected to strengthen Nokia&#39;s position as a leading telecommunications equipment provider in the region.
The stock has gained 16.7% over the past six months compared with the industry&#39;s growth of 12.9%.
<img alt="Zacks Investment Research" src="https://staticx-tuner.zacks.com/images/articles/charts/92/78441.jpg?v=1839641549" /> 
Image Source: Zacks Investment Research
<h2>NOK Zacks Rank &amp; Stocks to Consider</h2>
Nokia currently carries a Zacks Rank #3 (Hold).
Arista Networks, Inc. (NYSE: <a class="ticker" href="https://www.benzinga.com/stock/anet#NYSE">ANET</a>), carrying a Zacks Rank #2 (Buy) at present, is likely to benefit from strong momentum and diversification across its top verticals and product lines. The company has a software-driven, data-centric approach to help customers build their cloud architecture and enhance their cloud experiences. Arista has a long-term earnings growth expectation of 17.2% and delivered an earnings surprise of 15%, on average, in the trailing four quarters.
It holds a leadership position in 100-gigabit Ethernet switching share in port for the high-speed data center segment. Arista is increasingly gaining market traction in 200 and 400-gig high-performance switching products. It is well-positioned for healthy growth in data-driven cloud networking business with proactive platforms and predictive operations.
AudioCodes Ltd. (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/audc#NASDAQ">AUDC</a>) currently carries a Zacks Rank #2. It delivered an earnings surprise of 10.1%, on average, in the trailing four quarters.
Headquartered in Lod, Israel, AudioCodes offers advanced communications software, products and productivity solutions for the digital workplace. It provides a broad range of innovative products, solutions and services that are used by large multi-national enterprises and leading tier-1 operators around the world.
Airgain, Inc. (NASDAQ: <a class="ticker" href="https://www.benzinga.com/stock/airg#NASDAQ">AIRG</a>) currently carries a Zacks Rank #2. It has a long-term earnings growth expectation of 35%.
Headquartered in San Diego, CA, Airgain offers integrated wireless solutions in the form of antenna products. These products are equipped to solve critical connectivity needs in both the design process and the operating environment across the enterprise, automotive and consumer markets. Ideal for original equipment and design manufacturers, vertical markets, chipset vendors, service providers, value-added resellers and software developers worldwide, the customizable antennas from Airgain serve both indoor and outdoor connectivity issues.
<a href="https://www.zacks.com/stock/news/2338515/nokia-to-help-bridge-digital-divide-in-liberia-will-the-stock-gain?cid=CS-BENZ-FT-analyst_blog|company_news_tech_sector-2338515">To read this article on Zacks.com click here.</a>

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AUDC

Nokia to Help Bridge Digital Divide in Liberia: Will the Stock Gain?

Canaccord Genuity analyst Brian McNamara maintains Driven Brands Hldgs (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/DRVN#NASDAQ">DRVN</a>) with a Buy and raises the price target from $19 to $20.

DRVN

Canaccord Genuity Maintains Buy on Driven Brands Hldgs, Raises Price Target to $20

TD Cowen analyst Karl Ackerman maintains Micron Technology (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/MU#NASDAQ">MU</a>) with a Buy and lowers the price target from $160 to $115.

TD Cowen Maintains Buy on Micron Technology, Lowers Price Target to $115

Helix Energy Solutions shares are trading higher after Raymond James initiated coverage on the stock with a Strong Buy rating and announced a price target of $14.

Canaccord Genuity analyst Austin Moeller maintains Cibus (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CBUS#NASDAQ">CBUS</a>) with a Buy and lowers the price target from $21 to $20.

CBUS

Canaccord Genuity Maintains Buy on Cibus, Lowers Price Target to $20

Hut 8 Corp shares are trading higher after the company announced it expanded its partnership with BITMAIN to unveil the next-gen liquid-cooled ASIC miner for Bitcoin mining.

Boeing Co's (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/BA#NYSE">BA</a>) stock is flying low as the company battles a machinist strike that has forced tens of thousands of workers <a href="https://www.benzinga.com/quote/BA/news">off the job</a>. 
In a bid to cut costs, Boeing <a href="https://www.benzinga.com/markets/equities/24/09/40931613/boeing-enforces-temporary-furloughs-amid-strike-ceo-kelly-ortberg-announces-difficult-steps-like">has furloughed thousands</a> of U.S. employees, executives, and non-essential contractors. CEO Kelly Ortberg confirmed the furloughs in a memo, adding that these steps are necessary to preserve cash amid the ongoing labor disruption.
The strike began after more than 30,000 machinists in Seattle and Oregon rejected Boeing's latest contract offer, with 96% voting to walk off. Despite a 25% raise on the table, workers argued the offer failed to match the skyrocketing cost of living in the Seattle area. Negotiations remain tense, and the union's frustration is mounting.
<h2 class="wp-block-heading">Boeing Chart Suggests Turbulence Ahead</h2>
Boeing's stock price has been unable to lift off amid this chaos. At $155.30, BA is below its five, 20, and 50-day exponential moving averages (EMAs), signaling a strong bearish trend.
<figure class="wp-block-image size-full"><a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent091924&amp;t=be2bearmibe3na1"><img loading="lazy" decoding="async" width="623" height="454" src="https://editorial-assets.benzinga.com/wp-content/uploads/2024/09/19105209/Screenshot-2024-09-19-at-8.21.18-PM.png" alt="" class="wp-image-556505" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2024/09/19105209/Screenshot-2024-09-19-at-8.21.18-PM.png 623w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/09/19105209/Screenshot-2024-09-19-at-8.21.18-PM-300x219.png 300w" sizes="(max-width: 623px) 100vw, 623px" /></a></figure>
<a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent091924&amp;t=be2bearmibe3na1">Chart created using Benzinga Pro</a>
The eight-day simple moving average, at $157.91, and the 20-day SMA, at $164.06, all signal more downside ahead.
Additional dark clouds hover as the 50-day SMA is at $172.00, while the 200-day SMA sits at $192.33, indicating that Boeing's stock is technically bearish across the board.
Read Also: <a href="https://www.benzinga.com/news/24/09/40886979/boeing-stock-continues-to-fall-after-announcing-hiring-freeze-other-cost-cuts-amid-workers-strike">Boeing Stock Continues To Fall After Announcing Hiring Freeze, Other Cost Cuts Amid Workers&#8217; Strike</a>
<figure class="wp-block-image size-full"><a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent091924&amp;t=be2bearmibe3na1"><img loading="lazy" decoding="async" width="623" height="454" src="https://editorial-assets.benzinga.com/wp-content/uploads/2024/09/19105213/Screenshot-2024-09-19-at-8.21.32-PM.png" alt="" class="wp-image-556506" srcset="https://editorial-assets.benzinga.com/wp-content/uploads/2024/09/19105213/Screenshot-2024-09-19-at-8.21.32-PM.png 623w,https://editorial-assets.benzinga.com/wp-content/uploads/2024/09/19105213/Screenshot-2024-09-19-at-8.21.32-PM-300x219.png 300w" sizes="(max-width: 623px) 100vw, 623px" /></a></figure>
<a href="https://bzresearch.myclickfunnels.com/benzinga-pro-content-webinar-registration/?utm_source=BZprocontent091924&amp;t=be2bearmibe3na1">Chart created using Benzinga Pro</a>
The MACD (Moving Average Convergence/Divergence) is a negative 4.85, reinforcing the bearish momentum.
Boeing stock is currently nearing oversold territory, with an RSI of 36.57, indicating the potential for some short-term relief. However, this offers little comfort to investors at the moment.
Even the Bollinger Bands ($150.30 &#8211; $182.72) scream bearish, with Boeing stock trading in the lower band, signaling continued pressure.
As Boeing navigates this turbulence, investors may need to brace for further dips before clear skies return.
Read Next: 
<ul>
<li><a href="https://www.benzinga.com/news/24/09/40899599/elon-musk-said-spacex-competitors-only-take-up-less-than-we-do-and-they-take-nothing-down-and-they-g">Elon Musk Said SpaceX Competitors Only &#8216;Take Up Less Than We Do, And They Take Nothing Down, And They Get Paid Twice As Much&#8217; — 10 Years Later, Its Rival In Space Boeing Has Frozen Hiring And Is Weighing Furloughs</a></li>
</ul>
Photo: Shutterstock

Technicals

Boeing Braces For Turbulence As Strikes, Furloughs Send Stock Sliding, Bearish Signals Prevail

Larimar Therapeutics, Inc. - Common Stock

LRMR

Larimar Therapeutics shares are trading higher after the company announced that data from its Nomlabofusp Phase 1 studies and Phase 2 dose exploration will be presented at the annual International Congress for Ataxia Research.

Citigroup analyst James Hardiman maintains Harley-Davidson (NYSE:<a class="ticker" href="https://www.benzinga.com/stock/HOG#NYSE">HOG</a>) with a Neutral and raises the price target from $37 to $39.

Citigroup Maintains Neutral on Harley-Davidson, Raises Price Target to $39

<a href="https://www.ema.europa.eu/en/news/ema-recommends-extending-indication-mpox-vaccine-adolescents#:~:text=EMA%20has%20recommended%20extending%20the,the%20vaccinia%20virus%20in%20adults.">https://www.ema.europa.eu/en/news/ema-recommends-extending-indication-mpox-vaccine-adolescents#:~:text=EMA%20has%20recommended%20extending%20the,the%20vaccinia%20virus%20in%20adults.</a>
&nbsp;
EMA has recommended extending the indication of the smallpox and mpox vaccine <a href="https://www.ema.europa.eu/node/65501">Imvanex</a> to adolescents from 12 to 17 years of age.
Imvanex is already authorised in the European Union (EU) to protect against smallpox, mpox and the disease caused by the vaccinia virus in adults. It contains a live, highly weakened form of a virus called "modified vaccinia virus Ankara" (MVA-BN), which is related to the smallpox virus. EMA's human medicines committee (CHMP) based the recommendation to extend the use of Imvanex to adolescents on the <a href="https://www.clinicaltrials.gov/study/NCT05740982">interim results of a study</a> that compared the vaccine's ability to generate an immune response (produce virus-specific antibodies) in 315 adolescents and in 211 adults.
The immune response in adolescents was similar to adults. Therefore, it is inferred that the vaccine will provide similar protection in adolescents to that expected in adults. According to the submitted data, the safety profile of Imvanex in adolescents was comparable to that seen in adults and no additional risk has been identified. As part of its recommendation, EMA has requested the marketing authorisation holder to submit the final results of the study by 30 May 2025 to further characterise the information about safety in adolescents.
The Agency's assessment has important implications for the global response to the mpox outbreak in the Democratic Republic of the Congo (DRC) and other countries, which was <a href="https://www.who.int/news/item/14-08-2024-who-director-general-declares-mpox-outbreak-a-public-health-emergency-of-international-concern">declared a public health emergency of international concern (PHEIC)</a> by the World Health Organization (WHO) on 14 August 2024.
EMA is the regulatory agency of record for <a href="https://www.who.int/news/item/13-09-2024-who-prequalifies-the-first-vaccine-against-mpox">prequalification of this vaccine by WHO</a> on 13 September 2024. This means that CHMP's assessment constitutes the basis for WHO prequalification approval to facilitate timely and increased access to this vaccine in communities with urgent need. Previously, EMA's assessment was also taken into account by the national regulatory authority of the DRC in the fast-track approval of the vaccine. In addition, WHO has cooperated in EMA's assessment of the extension of indication in adolescents, a population that is particularly vulnerable to mpox.
Mpox is a disease that is transmitted to people by animals, mainly rodents, but can also spread between people with direct contact. It is endemic in certain parts of Central and West Africa. The current surge in cases in the DRC and several neighbouring countries is driven by the mpox clade I strain that is known to cause a more severe form of mpox in humans than the mpox clade II strain that spread during the 2022/2023 PHEIC. Mpox can be fatal for people with weak immune systems.
Data indicate that Imvanex protects against both the clade I and clade II mpox strains.
In the EU, decisions on how vaccinations should be given are the prerogative of the expert bodies guiding vaccination campaigns in each Member State. The European Centre for Disease Prevention and Control (ECDC) <a href="https://www.ecdc.europa.eu/en/infectious-disease-topics/mpox/rapid-scientific-advice-public-health-measures-mpox-2024">published advice for public health authorities for mpox</a> on their website.

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'EMA Recommends Extending Indication Of Mpox Vaccine To Adolescents' - EMA

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Applied Therapeutics shares are trading higher after Leerink Partners and Citigroup raised their respective price targets on the stock.

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Stifel Reiterates Buy on Vail Resorts, Lowers Price Target to $223

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<a href="https://www.sec.gov/newsroom/press-releases/2024-140" title="https://www.sec.gov/newsroom/press-releases/2024-140">https://www.sec.gov/newsroom/press-releases/2024-140</a>

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