| Jul 15, 2026 | Joana Goncalves | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $46.80 | $553K |
| Jul 13, 2026 | Arjun Agarwal | SENIOR VICE PRESIDENT, FINANCE | SELL-OPTIONS | — | $50.16 | $689K |
| Jul 1, 2026 | Fairmount Funds Management LLC, Fairmount Healthcare Fund II LP, Fairmount Healthcare CoInvest III LP, Tomas Kiselak, Evan Peter Harwin | DIRECTOR | SELL-OPTIONS | — | $84.43 | $300.0M |
| Jul 1, 2026 | Laura Sandler | CHIEF OPERATING OFFICER | SELL-OPTIONS | — | $51.11 | $433K |
| Jun 22, 2026 | Arjun Agarwal | SENIOR VICE PRESIDENT, FINANCE | SELL | 1.587K | $80.95 | $128K |
| Jun 15, 2026 | Joana Goncalves | CHIEF MEDICAL OFFICER | SELL | 947.000 | $38.30 | $499K |
| Jun 15, 2026 | Lawrence Klein | CHIEF EXECUTIVE OFFICER | SELL | 1.729K | $69.69 | $120K |
| Jun 15, 2026 | Laura Sandler | CHIEF OPERATING OFFICER | SELL | 600.000 | $69.69 | $42K |
| Jun 15, 2026 | Paul Quinlan | GENERAL COUNSEL | SELL | 733.000 | $69.69 | $51K |
| Jun 12, 2026 | Arjun Agarwal | SENIOR VICE PRESIDENT, FINANCE | SELL | 395.000 | $42.80 | $537K |
| Jun 11, 2026 | Carl Dambkowski | DIRECTOR | SELL | 35.000K | $70.13 | $2.5M |
| May 21, 2026 | Carl Dambkowski | DIRECTOR | SELL | 42.740K | $33.46 | $5.7M |
| May 18, 2026 | Arjun Agarwal | SENIOR VICE PRESIDENT, FINANCE | SELL | 2.457K | $43.93 | $382K |
| May 15, 2026 | Joana Goncalves | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $34.58 | $382K |
| May 1, 2026 | Laura Sandler | CHIEF OPERATING OFFICER | SELL-OPTIONS | — | $35.84 | $280K |
| Apr 15, 2026 | Joana Goncalves | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $36.72 | $412K |
| Mar 16, 2026 | Lawrence Klein | CHIEF EXECUTIVE OFFICER | SELL | 1.729K | $41.30 | $71K |
| Mar 16, 2026 | Arjun Agarwal | SENIOR VICE PRESIDENT, FINANCE | SELL | 395.000 | $41.30 | $16K |
| Mar 16, 2026 | Laura Sandler | CHIEF OPERATING OFFICER | SELL | 600.000 | $41.30 | $25K |
| Mar 16, 2026 | Joana Goncalves | CHIEF MEDICAL OFFICER | SELL | 641.000 | $24.11 | $261K |
| Mar 16, 2026 | Paul Quinlan | GENERAL COUNSEL | SELL | 733.000 | $41.30 | $30K |
| Mar 2, 2026 | Laura Sandler | CHIEF OPERATING OFFICER | SELL-OPTIONS | — | $20.68 | $129K |
| Feb 17, 2026 | Joana Goncalves | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $19.84 | $175K |
