Consensus Rating1
Buy
Highest Price Target1
$88.00
Lowest Price Target1
$27.00
Consensus Price Target1
$57.74

Ionis Pharmaceuticals Analyst Ratings and Price Targets | NASDAQ:IONS | Benzinga

Ionis Pharmaceuticals Inc has a consensus price target of $57.74 based on the ratings of 29 analysts. The high is $88 issued by Wells Fargo on May 4, 2023. The low is $27 issued by SVB Leerink on February 23, 2023. The 3 most-recent analyst ratings were released by JP Morgan, HC Wainwright & Co., and Guggenheim on June 12, 2025, May 20, 2025, and May 1, 2025, respectively. With an average price target of $54 between JP Morgan, HC Wainwright & Co., and Guggenheim, there's an implied 51.62% upside for Ionis Pharmaceuticals Inc from these most-recent analyst ratings.

Analyst Trends and Forecast
3
1
Feb
3
Mar
5
Apr
3
May
1
Jun
Buy
Hold
Sell
Strong Sell
Analyst Rating and Forecast
12345
3.3
Hold
Strong Buy
Buy
Hold
Sell
Strong Sell

Analyst Firms Making Recommendations1

JP Morgan
HC Wainwright & Co.
Guggenheim
Needham
Redburn Atlantic

1calculated from analyst ratings

Analyst Ratings for Ionis Pharmaceuticals

Buy NowGet Alert
06/12/2025Buy Now34.77%JP Morgan
Jessica Fye66%
$45 → $48MaintainsNeutralGet Alert
05/20/2025Buy Now40.39%HC Wainwright & Co.
Mitchell Kapoor46%
$50 → $50ReiteratesBuy → BuyGet Alert
05/01/2025Buy Now79.7%Guggenheim
Debjit Chattopadhyay56%
$65 → $64MaintainsBuyGet Alert
05/01/2025Buy Now40.39%HC Wainwright & Co.
Mitchell Kapoor46%
$45 → $50MaintainsBuyGet Alert
04/30/2025Buy Now54.43%Needham
Joseph Stringer62%
$60 → $55MaintainsBuyGet Alert
04/15/2025Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
04/08/2025Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
04/07/2025Buy Now26.35%HC Wainwright & Co.
Mitchell Kapoor46%
→ $45Initiates → BuyGet Alert
04/03/2025Buy NowGuggenheim
Debjit Chattopadhyay56%
ReiteratesBuy → BuyGet Alert
03/31/2025Buy Now9.5%Redburn Atlantic
Joshua Smith 64%
→ $39Initiates → NeutralGet Alert
03/24/2025Buy Now26.35%JP Morgan
Jessica Fye66%
$47 → $45MaintainsNeutralGet Alert
03/11/2025Buy Now31.97%JP Morgan
Jessica Fye66%
$51 → $47MaintainsNeutralGet Alert
02/20/2025Buy Now79.7%Citigroup
David Lebowitz54%
$67 → $64MaintainsBuyGet Alert
02/20/2025Buy Now96.55%RBC Capital
Luca Issi45%
$70 → $70ReiteratesOutperform → OutperformGet Alert
02/20/2025Buy Now26.35%BMO Capital
Kostas Biliouris35%
$60 → $45MaintainsMarket PerformGet Alert
02/20/2025Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
01/15/2025Buy Now96.55%RBC Capital
Luca Issi45%
$70 → $70ReiteratesOutperform → OutperformGet Alert
12/20/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60MaintainsBuyGet Alert
11/14/2024Buy Now74.08%Piper Sandler
Allison Bratzel71%
$65 → $62MaintainsOverweightGet Alert
11/07/2024Buy Now116.2%Wells Fargo
Yanan Zhu44%
$82 → $77MaintainsOverweightGet Alert
11/07/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
10/09/2024Buy Now82.51%Guggenheim
Debjit Chattopadhyay56%
$70 → $65MaintainsBuyGet Alert
09/26/2024Buy Now96.55%RBC Capital
Luca Issi45%
$70 → $70ReiteratesOutperform → OutperformGet Alert
08/26/2024Buy Now54.43%JP Morgan
Jessica Fye66%
$50 → $55MaintainsNeutralGet Alert
08/02/2024Buy Now96.55%Guggenheim
Debjit Chattopadhyay56%
$64 → $70MaintainsBuyGet Alert
08/02/2024Buy Now3.89%Goldman Sachs
Salveen Richter53%
$33 → $37MaintainsSellGet Alert
08/02/2024Buy Now43.2%Barclays
Gena Wang63%
$45 → $51MaintainsEqual-WeightGet Alert
08/02/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
08/02/2024Buy Now68.47%BMO Capital
Kostas Biliouris35%
$67 → $60DowngradeOutperform → Market PerformGet Alert
07/24/2024Buy Now74.08%Leerink Partners
Mani Foroohar48%
$53 → $62UpgradeMarket Perform → OutperformGet Alert
07/23/2024Buy Now65.66%TD Cowen
Yaron Werber38%
$54 → $59MaintainsBuyGet Alert
07/23/2024Buy Now90.93%B of A Securities
Jason Gerberry70%
$67 → $68MaintainsBuyGet Alert
07/22/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
07/16/2024Buy Now88.12%B of A Securities
Jason Gerberry70%
$64 → $67MaintainsBuyGet Alert
07/16/2024Buy Now110.59%Jefferies
Akash Tewari42%
$29 → $75UpgradeUnderperform → BuyGet Alert
06/27/2024Buy Now48.81%Stifel
Paul Matteis45%
$50 → $53MaintainsHoldGet Alert
06/14/2024Buy NowBernstein
William Pickering38%
UpgradeUnderperform → Market PerformGet Alert
06/03/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
05/08/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
05/08/2024Buy Now130.24%Wells Fargo
Yanan Zhu44%
$85 → $82MaintainsOverweightGet Alert
04/10/2024Buy NowWolfe Research
Andy Chen48%
UpgradePeer Perform → OutperformGet Alert
04/09/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
04/09/2024Buy Now110.59%Oppenheimer
Jay Olson60%
$72 → $75MaintainsOutperformGet Alert
03/06/2024Buy Now102.16%Oppenheimer
Jay Olson60%
$65 → $72MaintainsOutperformGet Alert
02/26/2024Buy Now82.51%Oppenheimer
Jay Olson60%
$63 → $65Reinstates → OutperformGet Alert
02/22/2024Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
02/22/2024Buy Now76.89%Piper Sandler
Do Kim54%
$62 → $63MaintainsOverweightGet Alert
02/01/2024Buy Now54.43%JP Morgan
Jessica Fye66%
$52 → $55MaintainsNeutralGet Alert
01/26/2024Buy Now96.55%RBC Capital
Luca Issi45%
$65 → $70MaintainsOutperformGet Alert
01/18/2024Buy Now74.08%Piper Sandler
Do Kim54%
$60 → $62MaintainsOverweightGet Alert
01/02/2024Buy Now74.08%B of A Securities
Jason Gerberry70%
$52 → $62UpgradeNeutral → BuyGet Alert
12/19/2023Buy Now68.47%Needham
Joseph Stringer62%
$60 → $60ReiteratesBuy → BuyGet Alert
12/18/2023Buy Now40.39%Stifel
Paul Matteis45%
$45 → $50MaintainsHoldGet Alert
11/17/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60ReiteratesBuy → BuyGet Alert
11/03/2023Buy Now-21.38%Goldman Sachs
Salveen Richter53%
$25 → $28MaintainsSellGet Alert
11/03/2023Buy Now34.77%Morgan Stanley
Michael Ulz66%
$45 → $48MaintainsEqual-WeightGet Alert
10/23/2023Buy Now46.01%B of A Securities
Jason Gerberry70%
$33 → $52UpgradeUnderperform → NeutralGet Alert
10/05/2023Buy Now82.51%RBC Capital
Luca Issi45%
→ $65ReiteratesOutperform → OutperformGet Alert
09/29/2023Buy Now76.89%Raymond James → $63Initiates → Strong BuyGet Alert
09/27/2023Buy Now26.35%Morgan Stanley
Michael Ulz66%
$42 → $45MaintainsEqual-WeightGet Alert
09/27/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60ReiteratesBuy → BuyGet Alert
08/10/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60ReiteratesBuy → BuyGet Alert
07/31/2023Buy Now68.47%Citigroup
David Lebowitz54%
$36 → $60UpgradeNeutral → BuyGet Alert
06/07/2023Buy Now62.85%Piper Sandler
Do Kim54%
→ $58Assumes → OverweightGet Alert
05/04/2023Buy Now82.51%RBC Capital
Luca Issi45%
→ $65Reiterates → OutperformGet Alert
05/04/2023Buy Now1.08%Citigroup
David Lebowitz54%
$30 → $36UpgradeSell → NeutralGet Alert
05/04/2023Buy Now147.09%Wells Fargo
Vanck Zhu75%
$92 → $88MaintainsOverweightGet Alert
05/04/2023Buy Now3.89%Barclays
Gena Wang63%
$40 → $37MaintainsEqual-WeightGet Alert
05/04/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60Reiterates → BuyGet Alert
04/25/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60Reiterates → BuyGet Alert
04/18/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60Reiterates → BuyGet Alert
04/11/2023Buy Now17.93%Morgan Stanley
Michael Ulz66%
$40 → $42MaintainsEqual-WeightGet Alert
03/21/2023Buy Now-12.96%Bernstein
William Pickering38%
→ $31Initiates → UnderperformGet Alert
02/23/2023Buy Now-24.19%SVB Leerink
Mani Foroohar48%
$34 → $27MaintainsMarket PerformGet Alert
02/23/2023Buy Now82.51%RBC Capital
Luca Issi45%
→ $65Reiterates → OutperformGet Alert
02/23/2023Buy Now88.12%BMO Capital
Gary Nachman60%
$70 → $67MaintainsOutperformGet Alert
02/23/2023Buy Now12.31%Barclays
Gena Wang63%
$44 → $40MaintainsEqual-WeightGet Alert
02/23/2023Buy Now68.47%Needham
Joseph Stringer62%
→ $60Reiterates → BuyGet Alert
02/03/2023Buy Now-4.53%SVB Leerink
Joseph Schwartz63%
$33 → $34MaintainsMarket PerformGet Alert
01/23/2023Buy Now-7.34%SVB Leerink
Mani Foroohar48%
$32 → $33MaintainsMarket PerformGet Alert
01/19/2023Buy Now74.08%Piper Sandler
Do Kim54%
$60 → $62MaintainsOverweightGet Alert
12/21/2022Buy Now12.31%Morgan Stanley
Michael Ulz66%
$56 → $40DowngradeOverweight → Equal-WeightGet Alert
11/10/2022Buy Now57.24%Morgan Stanley
Andrew Galler34%
$57 → $56MaintainsOverweightGet Alert
11/10/2022Buy Now-12.96%Citigroup
David Lebowitz54%
$28 → $31MaintainsSellGet Alert
11/10/2022Buy Now-27%SVB Leerink
Mani Foroohar48%
$30 → $26MaintainsMarket PerformGet Alert
09/09/2022Buy Now60.04%Morgan Stanley
Andrew Galler34%
$30 → $57UpgradeUnderweight → OverweightGet Alert
08/10/2022Buy Now-21.38%Citigroup
David Lebowitz54%
$26 → $28MaintainsSellGet Alert
08/10/2022Buy Now79.7%RBC Capital
Luca Issi45%
$67 → $64MaintainsOutperformGet Alert
07/26/2022Buy Now62.85%Piper Sandler
Do Kim54%
$55 → $58MaintainsOverweightGet Alert
07/18/2022Buy Now65.66%Oppenheimer
Justin Kim37%
→ $59Assumes → OutperformGet Alert
06/21/2022Buy Now-24.19%SVB Leerink
Mani Foroohar48%
$26 → $27MaintainsMarket PerformGet Alert

FAQ

Q

What is the target price for Ionis Pharmaceuticals (IONS) stock?

A

The latest price target for Ionis Pharmaceuticals (NASDAQ:IONS) was reported by JP Morgan on June 12, 2025. The analyst firm set a price target for $48.00 expecting IONS to rise to within 12 months (a possible 34.77% upside). 37 analyst firms have reported ratings in the last year.

Q

What is the most recent analyst rating for Ionis Pharmaceuticals (IONS)?

A

The latest analyst rating for Ionis Pharmaceuticals (NASDAQ:IONS) was provided by JP Morgan, and Ionis Pharmaceuticals maintained their neutral rating.

Q

When was the last upgrade for Ionis Pharmaceuticals (IONS)?

A

The last upgrade for Ionis Pharmaceuticals Inc happened on July 24, 2024 when Leerink Partners raised their price target to $62. Leerink Partners previously had a market perform for Ionis Pharmaceuticals Inc.

Q

When was the last downgrade for Ionis Pharmaceuticals (IONS)?

A

The last downgrade for Ionis Pharmaceuticals Inc happened on August 2, 2024 when BMO Capital changed their price target from $67 to $60 for Ionis Pharmaceuticals Inc.

Q

When is the next analyst rating going to be posted or updated for Ionis Pharmaceuticals (IONS)?

A

Analysts arrive at stock ratings after doing extensive research, which includes going through public financial statements, talking to executives and customers of Ionis Pharmaceuticals, and listening in to earnings conference calls. Most analysts do this every three months, so you should get 4 ratings per company per firm each year. The last rating for Ionis Pharmaceuticals was filed on June 12, 2025 so you should expect the next rating to be made available sometime around June 12, 2026.

Q

Is the Analyst Rating Ionis Pharmaceuticals (IONS) correct?

A

While ratings are subjective and will change, the latest Ionis Pharmaceuticals (IONS) rating was a maintained with a price target of $45.00 to $48.00. The current price Ionis Pharmaceuticals (IONS) is trading at is $35.62, which is out of the analyst’s predicted range.

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