Bulls vs Bears
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Ionis Pharmaceuticals Inc has a consensus price target of $57.74 based on the ratings of 29 analysts. The high is $88 issued by Wells Fargo on May 4, 2023. The low is $27 issued by SVB Leerink on February 23, 2023. The 3 most-recent analyst ratings were released by JP Morgan, HC Wainwright & Co., and Guggenheim on June 12, 2025, May 20, 2025, and May 1, 2025, respectively. With an average price target of $54 between JP Morgan, HC Wainwright & Co., and Guggenheim, there's an implied 51.62% upside for Ionis Pharmaceuticals Inc from these most-recent analyst ratings.
1calculated from analyst ratings
Buy Now | Get Alert | |||||||
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06/12/2025 | Buy Now | 34.77% | JP Morgan | Jessica Fye66% | $45 → $48 | Maintains | Neutral | Get Alert |
05/20/2025 | Buy Now | 40.39% | HC Wainwright & Co. | Mitchell Kapoor46% | $50 → $50 | Reiterates | Buy → Buy | Get Alert |
05/01/2025 | Buy Now | 79.7% | Guggenheim | Debjit Chattopadhyay56% | $65 → $64 | Maintains | Buy | Get Alert |
05/01/2025 | Buy Now | 40.39% | HC Wainwright & Co. | Mitchell Kapoor46% | $45 → $50 | Maintains | Buy | Get Alert |
04/30/2025 | Buy Now | 54.43% | Needham | Joseph Stringer62% | $60 → $55 | Maintains | Buy | Get Alert |
04/15/2025 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
04/08/2025 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
04/07/2025 | Buy Now | 26.35% | HC Wainwright & Co. | Mitchell Kapoor46% | → $45 | Initiates | → Buy | Get Alert |
04/03/2025 | Buy Now | — | Guggenheim | Debjit Chattopadhyay56% | — | Reiterates | Buy → Buy | Get Alert |
03/31/2025 | Buy Now | 9.5% | Redburn Atlantic | Joshua Smith 64% | → $39 | Initiates | → Neutral | Get Alert |
03/24/2025 | Buy Now | 26.35% | JP Morgan | Jessica Fye66% | $47 → $45 | Maintains | Neutral | Get Alert |
03/11/2025 | Buy Now | 31.97% | JP Morgan | Jessica Fye66% | $51 → $47 | Maintains | Neutral | Get Alert |
02/20/2025 | Buy Now | 79.7% | Citigroup | David Lebowitz54% | $67 → $64 | Maintains | Buy | Get Alert |
02/20/2025 | Buy Now | 96.55% | RBC Capital | Luca Issi45% | $70 → $70 | Reiterates | Outperform → Outperform | Get Alert |
02/20/2025 | Buy Now | 26.35% | BMO Capital | Kostas Biliouris35% | $60 → $45 | Maintains | Market Perform | Get Alert |
02/20/2025 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
01/15/2025 | Buy Now | 96.55% | RBC Capital | Luca Issi45% | $70 → $70 | Reiterates | Outperform → Outperform | Get Alert |
12/20/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Maintains | Buy | Get Alert |
11/14/2024 | Buy Now | 74.08% | Piper Sandler | Allison Bratzel71% | $65 → $62 | Maintains | Overweight | Get Alert |
11/07/2024 | Buy Now | 116.2% | Wells Fargo | Yanan Zhu44% | $82 → $77 | Maintains | Overweight | Get Alert |
11/07/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
10/09/2024 | Buy Now | 82.51% | Guggenheim | Debjit Chattopadhyay56% | $70 → $65 | Maintains | Buy | Get Alert |
09/26/2024 | Buy Now | 96.55% | RBC Capital | Luca Issi45% | $70 → $70 | Reiterates | Outperform → Outperform | Get Alert |
08/26/2024 | Buy Now | 54.43% | JP Morgan | Jessica Fye66% | $50 → $55 | Maintains | Neutral | Get Alert |
08/02/2024 | Buy Now | 96.55% | Guggenheim | Debjit Chattopadhyay56% | $64 → $70 | Maintains | Buy | Get Alert |
08/02/2024 | Buy Now | 3.89% | Goldman Sachs | Salveen Richter53% | $33 → $37 | Maintains | Sell | Get Alert |
08/02/2024 | Buy Now | 43.2% | Barclays | Gena Wang63% | $45 → $51 | Maintains | Equal-Weight | Get Alert |
08/02/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
08/02/2024 | Buy Now | 68.47% | BMO Capital | Kostas Biliouris35% | $67 → $60 | Downgrade | Outperform → Market Perform | Get Alert |
07/24/2024 | Buy Now | 74.08% | Leerink Partners | Mani Foroohar48% | $53 → $62 | Upgrade | Market Perform → Outperform | Get Alert |
07/23/2024 | Buy Now | 65.66% | TD Cowen | Yaron Werber38% | $54 → $59 | Maintains | Buy | Get Alert |
07/23/2024 | Buy Now | 90.93% | B of A Securities | Jason Gerberry70% | $67 → $68 | Maintains | Buy | Get Alert |
07/22/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
07/16/2024 | Buy Now | 88.12% | B of A Securities | Jason Gerberry70% | $64 → $67 | Maintains | Buy | Get Alert |
07/16/2024 | Buy Now | 110.59% | Jefferies | Akash Tewari42% | $29 → $75 | Upgrade | Underperform → Buy | Get Alert |
06/27/2024 | Buy Now | 48.81% | Stifel | Paul Matteis45% | $50 → $53 | Maintains | Hold | Get Alert |
06/14/2024 | Buy Now | — | Bernstein | William Pickering38% | — | Upgrade | Underperform → Market Perform | Get Alert |
06/03/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
05/08/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
05/08/2024 | Buy Now | 130.24% | Wells Fargo | Yanan Zhu44% | $85 → $82 | Maintains | Overweight | Get Alert |
04/10/2024 | Buy Now | — | Wolfe Research | Andy Chen48% | — | Upgrade | Peer Perform → Outperform | Get Alert |
04/09/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
04/09/2024 | Buy Now | 110.59% | Oppenheimer | Jay Olson60% | $72 → $75 | Maintains | Outperform | Get Alert |
03/06/2024 | Buy Now | 102.16% | Oppenheimer | Jay Olson60% | $65 → $72 | Maintains | Outperform | Get Alert |
02/26/2024 | Buy Now | 82.51% | Oppenheimer | Jay Olson60% | $63 → $65 | Reinstates | → Outperform | Get Alert |
02/22/2024 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
02/22/2024 | Buy Now | 76.89% | Piper Sandler | Do Kim54% | $62 → $63 | Maintains | Overweight | Get Alert |
02/01/2024 | Buy Now | 54.43% | JP Morgan | Jessica Fye66% | $52 → $55 | Maintains | Neutral | Get Alert |
01/26/2024 | Buy Now | 96.55% | RBC Capital | Luca Issi45% | $65 → $70 | Maintains | Outperform | Get Alert |
01/18/2024 | Buy Now | 74.08% | Piper Sandler | Do Kim54% | $60 → $62 | Maintains | Overweight | Get Alert |
01/02/2024 | Buy Now | 74.08% | B of A Securities | Jason Gerberry70% | $52 → $62 | Upgrade | Neutral → Buy | Get Alert |
12/19/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | $60 → $60 | Reiterates | Buy → Buy | Get Alert |
12/18/2023 | Buy Now | 40.39% | Stifel | Paul Matteis45% | $45 → $50 | Maintains | Hold | Get Alert |
11/17/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | Buy → Buy | Get Alert |
11/03/2023 | Buy Now | -21.38% | Goldman Sachs | Salveen Richter53% | $25 → $28 | Maintains | Sell | Get Alert |
11/03/2023 | Buy Now | 34.77% | Morgan Stanley | Michael Ulz66% | $45 → $48 | Maintains | Equal-Weight | Get Alert |
10/23/2023 | Buy Now | 46.01% | B of A Securities | Jason Gerberry70% | $33 → $52 | Upgrade | Underperform → Neutral | Get Alert |
10/05/2023 | Buy Now | 82.51% | RBC Capital | Luca Issi45% | → $65 | Reiterates | Outperform → Outperform | Get Alert |
09/29/2023 | Buy Now | 76.89% | Raymond James | — | → $63 | Initiates | → Strong Buy | Get Alert |
09/27/2023 | Buy Now | 26.35% | Morgan Stanley | Michael Ulz66% | $42 → $45 | Maintains | Equal-Weight | Get Alert |
09/27/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | Buy → Buy | Get Alert |
08/10/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | Buy → Buy | Get Alert |
07/31/2023 | Buy Now | 68.47% | Citigroup | David Lebowitz54% | $36 → $60 | Upgrade | Neutral → Buy | Get Alert |
06/07/2023 | Buy Now | 62.85% | Piper Sandler | Do Kim54% | → $58 | Assumes | → Overweight | Get Alert |
05/04/2023 | Buy Now | 82.51% | RBC Capital | Luca Issi45% | → $65 | Reiterates | → Outperform | Get Alert |
05/04/2023 | Buy Now | 1.08% | Citigroup | David Lebowitz54% | $30 → $36 | Upgrade | Sell → Neutral | Get Alert |
05/04/2023 | Buy Now | 147.09% | Wells Fargo | Vanck Zhu75% | $92 → $88 | Maintains | Overweight | Get Alert |
05/04/2023 | Buy Now | 3.89% | Barclays | Gena Wang63% | $40 → $37 | Maintains | Equal-Weight | Get Alert |
05/04/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | → Buy | Get Alert |
04/25/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | → Buy | Get Alert |
04/18/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | → Buy | Get Alert |
04/11/2023 | Buy Now | 17.93% | Morgan Stanley | Michael Ulz66% | $40 → $42 | Maintains | Equal-Weight | Get Alert |
03/21/2023 | Buy Now | -12.96% | Bernstein | William Pickering38% | → $31 | Initiates | → Underperform | Get Alert |
02/23/2023 | Buy Now | -24.19% | SVB Leerink | Mani Foroohar48% | $34 → $27 | Maintains | Market Perform | Get Alert |
02/23/2023 | Buy Now | 82.51% | RBC Capital | Luca Issi45% | → $65 | Reiterates | → Outperform | Get Alert |
02/23/2023 | Buy Now | 88.12% | BMO Capital | Gary Nachman60% | $70 → $67 | Maintains | Outperform | Get Alert |
02/23/2023 | Buy Now | 12.31% | Barclays | Gena Wang63% | $44 → $40 | Maintains | Equal-Weight | Get Alert |
02/23/2023 | Buy Now | 68.47% | Needham | Joseph Stringer62% | → $60 | Reiterates | → Buy | Get Alert |
02/03/2023 | Buy Now | -4.53% | SVB Leerink | Joseph Schwartz63% | $33 → $34 | Maintains | Market Perform | Get Alert |
01/23/2023 | Buy Now | -7.34% | SVB Leerink | Mani Foroohar48% | $32 → $33 | Maintains | Market Perform | Get Alert |
01/19/2023 | Buy Now | 74.08% | Piper Sandler | Do Kim54% | $60 → $62 | Maintains | Overweight | Get Alert |
12/21/2022 | Buy Now | 12.31% | Morgan Stanley | Michael Ulz66% | $56 → $40 | Downgrade | Overweight → Equal-Weight | Get Alert |
11/10/2022 | Buy Now | 57.24% | Morgan Stanley | Andrew Galler34% | $57 → $56 | Maintains | Overweight | Get Alert |
11/10/2022 | Buy Now | -12.96% | Citigroup | David Lebowitz54% | $28 → $31 | Maintains | Sell | Get Alert |
11/10/2022 | Buy Now | -27% | SVB Leerink | Mani Foroohar48% | $30 → $26 | Maintains | Market Perform | Get Alert |
09/09/2022 | Buy Now | 60.04% | Morgan Stanley | Andrew Galler34% | $30 → $57 | Upgrade | Underweight → Overweight | Get Alert |
08/10/2022 | Buy Now | -21.38% | Citigroup | David Lebowitz54% | $26 → $28 | Maintains | Sell | Get Alert |
08/10/2022 | Buy Now | 79.7% | RBC Capital | Luca Issi45% | $67 → $64 | Maintains | Outperform | Get Alert |
07/26/2022 | Buy Now | 62.85% | Piper Sandler | Do Kim54% | $55 → $58 | Maintains | Overweight | Get Alert |
07/18/2022 | Buy Now | 65.66% | Oppenheimer | Justin Kim37% | → $59 | Assumes | → Outperform | Get Alert |
06/21/2022 | Buy Now | -24.19% | SVB Leerink | Mani Foroohar48% | $26 → $27 | Maintains | Market Perform | Get Alert |
The latest price target for Ionis Pharmaceuticals (NASDAQ:IONS) was reported by JP Morgan on June 12, 2025. The analyst firm set a price target for $48.00 expecting IONS to rise to within 12 months (a possible 34.77% upside). 37 analyst firms have reported ratings in the last year.
The latest analyst rating for Ionis Pharmaceuticals (NASDAQ:IONS) was provided by JP Morgan, and Ionis Pharmaceuticals maintained their neutral rating.
The last upgrade for Ionis Pharmaceuticals Inc happened on July 24, 2024 when Leerink Partners raised their price target to $62. Leerink Partners previously had a market perform for Ionis Pharmaceuticals Inc.
The last downgrade for Ionis Pharmaceuticals Inc happened on August 2, 2024 when BMO Capital changed their price target from $67 to $60 for Ionis Pharmaceuticals Inc.
Analysts arrive at stock ratings after doing extensive research, which includes going through public financial statements, talking to executives and customers of Ionis Pharmaceuticals, and listening in to earnings conference calls. Most analysts do this every three months, so you should get 4 ratings per company per firm each year. The last rating for Ionis Pharmaceuticals was filed on June 12, 2025 so you should expect the next rating to be made available sometime around June 12, 2026.
While ratings are subjective and will change, the latest Ionis Pharmaceuticals (IONS) rating was a maintained with a price target of $45.00 to $48.00. The current price Ionis Pharmaceuticals (IONS) is trading at is $35.62, which is out of the analyst’s predicted range.
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