$79.76
-1.06-1.31%
At close: Dec 15, 4:00 PM EST
$79.76
N/A
After Hours: 4:03 PM EST

Short interest in Ionis Pharmaceuticals Inc (NASDAQ:IONS) increased during the last reporting period, rising from 14.22M to 15.63M. This put 12.73% of the company's publicly available shares short.
Based on the recent average volume of 2.62M shares traded per day, it would take 5.95 day(s) for holders of this short interest to close out their positions without sending the stock sharply higher.
| Get Alert | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| IONS | Ionis Pharmaceuticals, Inc. Co | 11/28/2025 | 12/09/2025 | 12.73% | 122,710,999 | 15,626,208 | 2,624,122 | 5.95 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 11/14/2025 | 11/25/2025 | 11.59% | 122,710,999 | 14,223,973 | 3,736,097 | 3.81 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 10/31/2025 | 11/11/2025 | 10.32% | 122,710,999 | 12,661,274 | 1,914,799 | 6.61 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 10/15/2025 | 10/24/2025 | 11.40% | 120,127,835 | 13,699,358 | 2,279,250 | 6.01 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 09/30/2025 | 10/09/2025 | 10.22% | 120,127,835 | 12,278,792 | 1,991,945 | 6.16 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 09/15/2025 | 09/24/2025 | 9.97% | 120,127,835 | 11,972,594 | 4,802,271 | 2.49 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 08/29/2025 | 09/10/2025 | 8.74% | 120,127,835 | 10,502,338 | 1,766,631 | 5.94 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 08/15/2025 | 08/26/2025 | 8.98% | 120,127,835 | 10,785,168 | 2,150,609 | 5.01 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 07/31/2025 | 08/11/2025 | 9.64% | 120,127,835 | 11,580,340 | 1,778,123 | 6.51 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 07/15/2025 | 07/24/2025 | 9.45% | 136,328,661 | 12,889,193 | 2,201,808 | 5.85 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 06/30/2025 | 07/10/2025 | 10.37% | 136,328,661 | 14,139,627 | 1,956,419 | 7.23 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 06/13/2025 | 06/25/2025 | 10.43% | 136,328,661 | 14,225,565 | 1,430,495 | 9.94 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 05/30/2025 | 06/10/2025 | 10.88% | 136,328,661 | 14,836,205 | 1,410,037 | 10.52 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 05/15/2025 | 05/27/2025 | 11.20% | 136,328,661 | 15,266,156 | 1,630,549 | 9.36 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 04/30/2025 | 05/09/2025 | 10.73% | 136,328,661 | 14,629,509 | 1,411,113 | 10.37 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 04/15/2025 | 04/25/2025 | 10.67% | 136,328,661 | 14,547,282 | 2,356,410 | 6.17 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 03/31/2025 | 04/09/2025 | 9.78% | 136,328,661 | 13,336,000 | 1,395,099 | 9.56 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 03/14/2025 | 03/25/2025 | 9.40% | 136,328,661 | 12,814,848 | 1,708,250 | 7.5 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 02/28/2025 | 03/11/2025 | 9.43% | 136,328,661 | 12,853,622 | 2,018,209 | 6.37 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 02/14/2025 | 02/26/2025 | 9.30% | 136,328,661 | 12,673,485 | 1,340,248 | 9.46 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 01/31/2025 | 02/11/2025 | 8.96% | 135,261,176 | 12,124,536 | 1,831,301 | 6.62 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 01/15/2025 | 01/27/2025 | 7.57% | 135,261,176 | 10,239,965 | 1,408,358 | 7.27 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 12/31/2024 | 01/10/2025 | 8.06% | 135,261,176 | 10,901,561 | 1,682,606 | 6.48 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 12/13/2024 | 12/24/2024 | 7.78% | 135,261,176 | 10,528,956 | 1,379,548 | 7.63 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 11/29/2024 | 12/10/2024 | 7.72% | 135,261,176 | 10,448,423 | 1,633,097 | 6.4 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 11/15/2024 | 11/26/2024 | 8.17% | 135,261,176 | 11,050,361 | 1,195,779 | 9.24 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 10/31/2024 | 11/11/2024 | 7.94% | 135,261,176 | 10,740,418 | 1,210,170 | 8.88 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 10/15/2024 | 10/24/2024 | 7.31% | 135,074,980 | 9,869,851 | 1,420,544 | 6.95 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 09/30/2024 | 10/09/2024 | 7.80% | 135,074,980 | 10,533,799 | 1,814,522 | 5.81 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 09/13/2024 | 09/24/2024 | 7.86% | 135,074,980 | 10,614,257 | 3,008,213 | 3.53 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 08/30/2024 | 09/11/2024 | 8.22% | 123,574,980 | 10,159,853 | 911,068 | 11.15 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 08/15/2024 | 08/26/2024 | 8.01% | 123,574,980 | 9,902,786 | 1,131,816 | 8.75 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 07/31/2024 | 08/09/2024 | 7.66% | 123,574,980 | 9,461,204 | 1,310,348 | 7.22 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 07/15/2024 | 07/24/2024 | 7.59% | 123,329,263 | 9,365,346 | 1,294,930 | 7.23 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 06/28/2024 | 07/10/2024 | 7.72% | 123,329,263 | 9,520,997 | 2,063,118 | 4.61 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 06/14/2024 | 06/26/2024 | 7.02% | 123,329,263 | 8,653,199 | 935,006 | 9.25 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 05/31/2024 | 06/11/2024 | 6.97% | 123,329,263 | 8,597,493 | 1,356,240 | 6.34 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 05/15/2024 | 05/24/2024 | 6.99% | 123,329,263 | 8,625,854 | 1,102,677 | 7.82 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 04/30/2024 | 05/09/2024 | 7.10% | 123,329,263 | 8,753,675 | 846,483 | 10.34 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 04/15/2024 | 04/24/2024 | 7.74% | 123,209,741 | 9,534,366 | 883,254 | 10.79 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 03/28/2024 | 04/09/2024 | 7.71% | 123,472,803 | 9,522,759 | 952,663 | 10 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 03/15/2024 | 03/26/2024 | 7.83% | 123,472,803 | 9,665,680 | 1,078,789 | 8.96 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 02/29/2024 | 03/11/2024 | 7.38% | 123,472,803 | 9,106,796 | 1,643,039 | 5.54 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 02/15/2024 | 02/27/2024 | 7.34% | 123,472,803 | 9,064,713 | 1,025,039 | 8.84 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 01/31/2024 | 02/09/2024 | 6.97% | 121,193,125 | 8,451,609 | 1,304,996 | 6.48 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 01/12/2024 | 01/24/2024 | 7.05% | 121,193,125 | 8,543,328 | 1,195,918 | 7.14 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 12/29/2023 | 01/10/2024 | 6.80% | 121,193,125 | 8,242,800 | 1,091,677 | 7.55 | Get Alert |
| IONS | Ionis Pharmaceuticals, Inc. Co | 12/15/2023 | 12/27/2023 | 7.07% | 121,193,125 | 8,563,127 | 1,247,402 | 6.86 | Get Alert |
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