48 Stocks Moving In Wednesday's Mid-Day Session

Gainers

• Akari Therapeutics PLC AKTX shares climbed 100.7 percent to $3.6522 after the company had a successful Type B, pre-IND meeting with the FDA regarding Akari's proposed pivotal clinical trial program for hematopoietic stem cell transplant-related thrombotic microangiopathy.
• Clean Energy Fuels Corp. CLNE climbed 21.6 percent to $2.76 after the company reported better-than-expected Q4 EPS and sales results. The company also issued FY19 EBITDA guidance of $50 million to $55 million.
• Novume Solutions Inc NVMM shares gained 21.5 percent to $0.8040.
• Pareteum Corporation TEUM shares climbed 21.1 percent to $4.7350 after the company reported better-than-expected Q4 EPS and sales results.
• Natera, Inc. NTRA rose 20.2 percent to $20.03 after the company reported better-than-expected Q4 EPS and sales results. The company also issued FY19 guidance in-line with analyst estimates.
• Vera Bradley, Inc. VRA gained 18.5 percent to $13.25 after the company reported better-than-expected Q4 EPS and sales and issued strong FY20 guidance.
• Diffusion Pharmaceuticals Inc. DFFN rose 17.8 percent to $5.74.
• Guardant Health Inc GH gained 13.2 percent to $83.80 after the company reported better-than-expected Q4 results. The company also issued FY19 sales guidance above analyst estimates.
• Aurora Cannabis Inc. ACB rose 11.5 percent to $8.87 after the company appointed activist investor Nelson Peltz as a strategic advisor.
• PhaseBio Pharmaceuticals, Inc. PHAS gained 11.1 percent to $3.00.
• Cara Therapeutics, Inc. CARA climbed 10.4 percent to $19.25 after the company reported better-than-expected Q4 EPS and sales results.
• Pyxus International, Inc. PYX shares gained 9.2 percent to $30.54.
• Lexicon Pharmaceuticals, Inc. LXRX rose 7.4 percent to $7.70 after the company reported better-than-expected Q4 EPS and sales results..
• Denali Therapeutics Inc. DNLI shares rose 7.1 percent to $23.76. On Tuesday, Denali Therapeutics reported Q4 EPS results increased 206% from last year.
• Aspen Aerogels, Inc. ASPN climbed 6.7 percent to $3.18 after the company reported winning of patent lawsuits against Chinese manufacturers.
• Cool Holdings, Inc. AWSM rose 6.4 percent to $4.16.
• Team, Inc. TISI shares surged 5.3 percent to $17.90 following Q4 results.
• Rite Aid Corporation RAD gained 5.1 percent to $0.7135 after the company announced leadership transition and organizational restructuring. The company expects to generate $55 million in annual cost savings through this restructuring.
• Aerie Pharmaceuticals, Inc. AERI rose 4.8 percent to $48.00. Aerie Pharmaceuticals said the FDA approved its Rocklatan, or netarsudil and latanoprost ophthalmic solution, 0.02%/0.05%, as a treatment option for reducing elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Separately, the company announced net cash burn and net revenue guidance for 2019, accounting for the Rocklatan launch, expecting net cash burn at $130 million to $140 million and net revenues at $110 million to $120 million.

Check out these big penny stock gainers and losers

Losers

• VivoPower International PLC VVPR shares declined 28.3 percent to $1.90 after rising 126.50 percent on Tuesday.
• Datasea Inc. DTSS shares fell 26.3 percent to $2.50.
• Sientra, Inc. SIEN shares dipped 23.2 percent to $8.74 after the company reported lower-than-expected Q4 EPS results.
• Harrow Health, Inc. HROW shares fell 19.3 percent to $5.50 after reporting Q4 results.
• Ocean Power Technologies, Inc. OPTT shares fell 18.4 percent to $5.71.
• Navios Maritime Holdings Inc. NM shares dropped 18 percent to $2.2800 after climbing 15.83 percent on Tuesday.
• INSYS Therapeutics, Inc. INSY shares dropped 16.9 percent to $4.72 after the company disclosed in its annual filing that the auditor's opinion on their audited financial statements included a paragraph stating concerns of the company's ability to continue as a going concern.
• BlueLinx Holdings Inc. BXC dropped 15.9 percent to $26.00 following Q4 results. Bluelinx posted a Q4 loss of $1.74 per share on sales of $672.64 million.
• Pinduoduo Inc. PDD fell 15.8 percent to $25.63 after reporting wider-than-expected Q4 loss.
• Synchronoss Technologies, Inc. SNCR shares fell 15.5 percent to $6.97 after reporting lower-than-expected earnings and sales for its fourth quarter.
• Amphastar Pharmaceuticals, Inc. AMPH fell 14.8 percent to $20.60 following Q4 results.
• Neovasc Inc NVCN shares dipped 12 percent to $0.4650. Neovasc priced its 11.11 million share common stock offering at $0.45 per share.
• Mannatech, Incorporated MTEX shares fell 12 percent to $17.34. Mannatech posted a Q4 loss of $0.66 per share on sales of $44.042 million.
• Clearwater Paper Corp CLW fell 11.6 percent to $23.54 following Q4 results.
• Castor Maritime Inc. CTRM shares declined 11.5 percent to $5.53.
• Noah Holdings Limited NOAH dipped 11.3 percent to $47.60 following Q4 results.
• Pacific Ethanol Inc PEIX fell 11.2 percent to $1.1900 after the company reported lower-than-expected Q4 EPS and sales results.
• ZAGG Inc ZAGG dipped 10.9 percent to $9.65. ZAGG posted upbeat Q4 results, but issued weak FY19 earnings forecast.
• Globus Maritime Limited GLBS shares fell 10 percent to $6.30.
• Lipocine Inc. LPCN shares tumbled 9.8 percent to $2.0288.
• Coffee Holding Co., Inc. JVA dropped 9.7 percent to $6.05 following downbeat Q1 results.
• Verastem, Inc. VSTM fell 9.6 percent to $2.9300 after the company reported lower-than-expected Q4 sales results.
• Lipocine Inc. LPCN declined 9.3 percent to $2.0399.
• Seelos Therapeutics, Inc. SEEL fell 9.1 percent to $3.50 after surging 20.31 percent on Tuesday.
• SAExploration Holdings, Inc. SAEX shares dropped 8 percent to $4.48.
• Quorum Health Corp QHC fell 7 percent to $1.86 after reporting Q4 results.
• ZTO Express (Cayman) Inc. ZTO fell 6.5 percent to $18.72 after reporting Q4 results.
• Trevena Inc TRVN fell 4.6 percent to $1.4022 following downbeat Q4 results.
• Express, Inc. EXPR fell 4 percent to $4.84 after the company reported downbeat Q4 sales and issued weak forecast for the first quarter.