Incyte Announces Positive Phase II Clinical Trial Results of Oral JAK1 Inhibitor in Patients with Active RA

Incyte Corporation

announced results from a 12-week, placebo-controlled, dose-escalation Phase II proof-of-concept clinical trial involving 60 patients with active rheumatoid arthritis for its proprietary oral JAK1 inhibitor. These results were presented today at the 2013 American College of Rheumatology / Association of Rheumatology Health Professionals (ACR/ARHP) Annual Scientific Meeting being held in San Diego, CA, from Oct. 25 to 30, 2013. “Along with our recently presented data with INCB39110 in psoriasis, results from this study in rheumatoid arthritis demonstrate the potential of JAK1 inhibition in inflammatory indications,” stated Richard S. Levy, Incyte's Executive Vice President and Chief Drug Development and Medical Officer.