Gilead's Biktarvy Demonstrates High Efficacy In HIV/HBV Coinfection Patients

Gilead's Biktarvy Demonstrates High Efficacy In HIV/HBV Coinfection Patients
  • Gilead Sciences Inc GILD announced results reinforcing Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) as a highly efficacious treatment option for HIV, including individuals with HIV/hepatitis B (HBV) coinfection. 
  • Interim data from the ALLIANCE trial evaluating Biktarvy in adults with HIV/HBV coinfection who were initiating therapy show potential HBV and HIV suppression comparable to an alternative HIV regimen. 
  • Related: Gilead Again Seeks HIV Drug Approval From FDA After Addressing Vial Compatibility Issues.
  • Additionally, 5-year data from two Phase 3 trials further demonstrated Biktarvy's sustained efficacy, safety profile, and high barrier to resistance in adults with HIV initiating therapy.
  • Participants who initiated treatment with Biktarvy versus DTG+F/TDF demonstrated superior HBV DNA suppression (63% vs. 43%) and hepatitis B e-antigen (HBeAg) seroconversion (23% vs. 11%).
  • No cases of treatment failure due to emergent resistance were detected in an analysis of five years of data.
  • Also Read: Why Gilead Is Cheapest Large-Cap Biotech Despite Some Not So Favorable Acquisitions.
  • Price Action: GILD shares are down 0.36% at $60.67 during the market session on the last check Thursday.

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