Theravance Biopharma Pulls Plug On Izencitinib Crohn's Disease Trial

  • Theravance Biopharma Inc TBPH has voluntarily discontinued its Phase 2 study of izencitinib (gut-selective oral pan-JAK inhibitor) in Crohn’s disease (Study 0173). 
  • The decision follows the planned review of trial data by the independent data monitoring committee, which determined concerns about the ongoing benefit-risk of continuing the trial. 
  • The committee, while, said there were no safety concerns.
  • Related Link: Theravance Stock Plunges As JAK Inhibitor Flops Ulcerative Colitis Study.
  • Price Action: TBPH shares are down 2.80% at $7.99 during the premarket session on the last check Tuesday.
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