Lilly's Olumiant Found to Lower Pain In Late-Stage Rheumatoid Arthritis Trial

  • Eli Lilly And Co LLY has reported posthoc analyses data from the Phase 3 RA-BEAM study that showed Olumiant 4mg (baricitinib) lowered pain and duration of morning joint stiffness in moderate to severe rheumatoid arthritis (RA) patients.
  • Discovered by Incyte Corporation INCY and licensed to Lilly, Olumiant is an oral Janus kinase (JAK) inhibitor approved for treating moderately to severely active RA in adults.
  • Trial data showed that Olumiant also enhanced overall physical function at 12 weeks compared to adalimumab and placebo.
  • The changes in pain relief were not affected by disease activity during treatment, Lilly noted.
  • Furthermore, subjects receiving Olumiant had greater improvements in fatigue versus placebo, and the improvements were comparable to AbbVie Inc's ABBV Humira after 12 weeks.
  • Price Action: LLY shares are up 0.47% at $199.35 during the market session on the last check Wednesday.
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Posted In: BiotechNewsHealth CareFDAGeneralBriefsPhase 3 Trialrheumatoid arthritis
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