Chimerix (NASDAQ:CMRX) Stock, Quote.Headers.trade-ideas

Chimerix

Chimerix Inc. is a biopharmaceutical company based in the United States that engages in the research, development, and commercialization of medicines. Its portfolio includes treatment for acute myeloid leukemia (or AML) and antiviral treatment for smallpox. The company generates revenue through revenue related to non-refundable upfront fees, royalties and milestone payments earned under license agreements, also by royalty revenue related to sales of TEMBEXA made by Emergent after the Asset Sale. The company operates only in one business segment namely pharmaceuticals.

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The Dow Jones closed lower by around 388 points on Tuesday. When insiders purchase or sell shares, it indicates their confidence or concern around the company&#39;s prospects. Investors and traders interested in penny stocks can consider this a factor in their overall investment or trading decision.

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The collapse of SVB Financial Group (NASDAQ: SIVB) could have a ripple effect on the technology and biotech industries, the two largest sectors that had deposits and financial relationships with the company’s Silicon Valley Bank.

Roku Has 26% Of Cash With SVB Financial, Deposit Recovery Uncertain — 27 Other Companies With Ties To Collapsed Bank

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Shares of Sunrun Inc (NASDAQ: RUN), the largest residential solar developer in the U.S, fell by as much as 15% on Friday as a result of the news that Silicon Valley Bank has been closed by the 

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Morocco Records First Case Of Mpox

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CDC Says There Have Been No Reported Cases Of Clade I Mpox In The U.S. As Of September 6; In The U.S., Clade II Mpox Is Still Circulating At Low Levels

<a href="https://www.nbcnews.com/health/health-news/us-prepares-possible-arrival-severe-strain-mpox-rcna169926">https://www.nbcnews.com/health/health-news/us-prepares-possible-arrival-severe-strain-mpox-rcna169926</a>
&nbsp;
Senior Biden administration officials said Friday that the United States is preparing for the possible arrival of <a href="https://www.nbcnews.com/health/health-news/mpox-strain-spreads-cdc-who-stronger-warnings-rcna165155">a more severe version of mpox</a>, which has taken off in the Democratic Republic of Congo and other countries in Africa resulting in more than 600 deaths there.
As of Thursday, there have been more than 24,800 reported cases of this version of the virus, <a href="https://www.nbcnews.com/health/health-news/mpox-virus-outbreak-symptoms-2024-spread-rcna166778">known as clade 1</a>, so far this year, the World Health Organization said at a separate briefing Friday.&nbsp;The WHO declared the outbreak a<a href="https://www.nbcnews.com/health/health-news/who-declares-mpox-global-public-health-emergency-second-time-rcna166601"> global health emergency</a> in August.
Last month,<a href="https://www.nbcnews.com/health/health-news/sweden-confirms-first-case-mpox-strain-congo-rcna166763"> Sweden confirmed a case of clade 1</a>, the first known case outside of Africa, followed by a case in Thailand several days later. Both patients had spent time in Africa.
A different version of mpox, clade 2, triggered a global outbreak in 2022 and a surge of cases in the U.S. Clade 1 is more severe and can kill up to 10% of people infected, though recent death rates have been around 1% to 3.3%, <a href="https://www.cdc.gov/poxvirus/mpox/about/index.html">according to the CDC.</a>
On a call with reporters, senior administration officials said that as infections have risen in Africa, the U.S. has been gearing up for its own cases.&nbsp;
"We've been preparing for the arrival of clade 1 in the United States for many months now, especially as we saw the outbreak in DRC and neighboring countries accelerate," one official said.
The government is expanding its mpox surveillance efforts, primarily through wastewater analysis, and is reaching out to the medical community to educate members on what to watch for, including the severity of clade 1 and how it spreads, according to officials.
Officials said they're also making sure testing is more widely available.
Any doctor in the U.S. can order an mpox test that can be run through a national laboratory. If positive, it can be tested for clade 2. If those results are negative for clade 2, the doctor can make a presumptive diagnosis of clade 1; that diagnosis will need to be officially confirmed by the Centers for Disease Control and Prevention, according to officials.
The Jynneos mpox vaccine, given in two doses, is effective against both clade 1 and clade 2 of mpox.
The CDC's vaccine recommendation remains limited to anyone who is considered at high risk of catching the virus, mainly gay and bisexual men.&nbsp;
Most people with health insurance can get the vaccine at major pharmacy retail chains including CVS and Walgreens, the officials said. The vaccine is also available for free at public health departments and community health centers.
More vaccines are being held in the U.S. national stockpile, officials said, although they declined to say how many.&nbsp;
"There is a sufficient amount of vaccine for the U.S. population," an official said.&nbsp;
The U.S. is also working with government scientists and drug companies to develop potential new treatments. There are currently no approved treatments for mpox. The Food and Drug Administration has approved an antiviral treatment known as TPOXX for smallpox, which is closely related to mpox, although a recent clinical trial found that the drug is <a href="https://www.nih.gov/news-events/news-releases/antiviral-tecovirimat-safe-did-not-improve-clade-i-mpox-resolution-democratic-republic-congo">not effective against clade 1</a>.&nbsp;

'U.S. Prepares For Possible Arrival Of More Severe Strain Of Mpox; There Have Been Nearly 25,000 Cases Of The Clade 1 Version Of Mpox In Africa So Far This Year" - NBC

<a href="https://ec.europa.eu/commission/presscorner/detail/en/ip_24_4523">https://ec.europa.eu/commission/presscorner/detail/en/ip_24_4523</a>
&nbsp;
Today, close to 100,000 mpox vaccine doses will arrive in the Democratic Republic of Congo (DRC), making these the first delivery of the vaccine to the country. A second delivery amounting to around 100,000 vaccines is expected to arrive in the coming days.
These vaccines are part of the 215,000 MVA-BN&#xAE; <a href="https://ec.europa.eu/commission/presscorner/detail/en/ip_24_4244">vaccine doses</a> that the European Commission's Health Emergency Preparedness and Response Authority (HERA) procured and pledged to share to affected countries in Africa as an immediate response to the mpox outbreak.
Via Team Europe, an additional 351,500 of doses from France, Germany, Spain, Malta, Portugal, Luxembourg, Croatia, Austria, Poland, and potentially some other Member States, will be donated to the Africa CDC to distribute to affected countries. This brings the total number of vaccine doses donated from Team Europe to at least 566,500, which includes the above 215,000 doses that were donated by HERA in cooperation with the Bavarian Nordic pharmaceutical company.
EU support for the mpox outbreak
This initiative is part of a comprehensive set of EU actions put in place as part of the EU Global Health Strategy, which represents the external dimension of a strong European Health Union and is a key component of Global Gateway, to support partners in the rest of the world.
The Commission is actively coordinating the response of EU Member States to the mpox outbreak via regular meetings of the HERA Board and the Health Security Committee, which allows prompt coordination when dealing with health threats.
The Emergency Response Coordination Centre (ERCC) is in contact with EU Member States given that, if activated, the EU Civil Protection Mechanism (rescEU) can be used to channel mpox vaccines and therapeutics to countries in need. Specialised expertise, medical items and equipment could also be deployed based on these needs.
Under the Global Gateway investment strategy, the Commission is committed to advancing public health in Africa. The Commission has focused on strengthening health systems, securing pharmaceutical supply chains, and developing local manufacturing through investment in infrastructure and a supportive regulatory environment. An example of this is the Team Europe Initiative on manufacturing and access to vaccines, medicines and health technologies (Mav+) and on Sustainable Health Security.
The European Centre for Disease Prevention and Control (ECDC) is supporting epidemiological work on the ground in the DRC, working with the Africa CDC to identify priority areas for mpox research, and is leading coordination of the Network of Major CDCs globally. HERA is also working with the Africa CDC with the aim of expanding access to mpox diagnostics and sequencing in the region, with a €9.4 million grant foreseen for early autumn.
The Commission has released €1 million in humanitarian aid to support care, prevention, epidemiological surveillance, risk communication and distribution of kits in the eastern DRC as well as €200,000 in Burundi to assist the Burundi Red Cross in preparing for and responding to the epidemic. Under the European Humanitarian Response Capacity (EHRC), in cooperation with the ECDC, two epidemiologists were deployed on 4 September to the DRC. In addition, the Commission provides regular humanitarian funding for surveillance programmes, including in Uganda and Kenya's camps and settlements and expertise to assist in the response.

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'First Delivery Of Mpox Vaccine Doses From The Commission Arrive Today In The Democratic Republic Of Congo' - European Commission

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WHO Chief Tedros Says Mpox Vaccines Could Be Ready For Emergency Use Listing Within Two Weeks; Some Mpox Vaccines Expected To Arrive In Congo In The Next Few Days

WHO Chief Tedros Says Received First Expression Of Interest For Emergency Use Listing From Mpox Diagnostics Manufacturer; WHO Officials Discuss Polio Vaccination Plan In Gaza, Confirm Applications From Bavarian Nordic And KM Biologics For Mpox Vaccines Emergency Use Listing, And Announce 230,000 Doses Available For Congo

CDC Says Clade I Mpox Outbreak Originating In Central Africa; Risk Of Mpox Coming Into U.S. Is Low; No Cases Of Clade I Mpox Have Been Reported In The U.S. At This Time; Best Protection Against Mpox Is Two Doses Of Jynneos Vaccine If Eligible; Working With Other U.S. Government Agencies & Partners On Strategy For Vaccination In Democratic Republic Of Congo

<a href="https://www.reviewjournal.com/life/health/mpox-case-reported-at-clark-county-detention-center-3148320/">https://www.reviewjournal.com/life/health/mpox-case-reported-at-clark-county-detention-center-3148320/</a>
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One case of mpox has been reported at the Clark County Detention Center, according to the Metropolitan Police Department.
While police were unable to confirm which date the case was reported, Metro said it was during the week of August 19.
The person with mpox, which is formerly known as monkeypox, is no longer in custody, police said Tuesday, adding that there were no other reported cases.
&nbsp;
According to the Centers for Disease Control, the virus is part of the same family as the virus that causes smallpox. Symptoms commonly include a rash that scabs before healing.
The disease can be spread between animals and people, the <a href="https://www.cdc.gov/poxvirus/mpox/about/index.html">CDC</a> website reads. It is spread through skin-to-skin contact.

Reported August 27, 2024 'Mpox Case Reported At Clark County Detention Center' - Las Vegas Review-Journal

WHO Launches Global Strategic Preparedness And Response Plan To Contain Mpox Outbreak

<a href="https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-member-states-information-session-on-mpox-23-august-2024">https://www.who.int/director-general/speeches/detail/who-director-general-s-opening-remarks-at-member-states-information-session-on-mpox-23-august-2024</a>
Honourable Ministers, Excellencies, dear colleagues and friends,
Good morning, good afternoon and good evening to all Member States, and thank you for joining us once again.
Since the start of the global mpox outbreak in 2022, more than one hundred thousand confirmed mpox cases have been reported to WHO.
The virus continues to circulate at low levels globally.
The African Region has had an unprecedented increase and geographical expansion.
Transmission is now centred in the Democratic Republic of the Congo, with 90% of the reported cases in 2024. There have been more than sixteen thousand suspected cases - including 575 deaths - this year alone.
This upsurge is being driven by two separate outbreaks – in different parts of the country - of two strains, or clades, of the virus that causes mpox.
The rapid spread of a new clade, clade 1b, is the main reason for my decision to declare a public health emergency of international concern, following the International Health Regulations Emergency Committee meeting on the 14th of August 2024.
I issued temporary recommendations five days later.
In the past month, cases of clade 1b have been reported in four countries neighbouring DRC, which had not reported mpox before: Burundi, Kenya, Rwanda and Uganda.
This week, cases have also been reported in Thailand and Sweden.
WHO and partners have developed a Global Mpox Strategic Preparedness and Response Plan to stop outbreaks of human-to-human transmission of mpox through coordinated global, regional, and national efforts.
The plan focuses on implementing comprehensive surveillance and response strategies; advancing research and equitable access to medical countermeasures; minimizing zoonotic transmission; and empowering communities to actively participate in outbreak prevention and control.
At the global-level, the emphasis is on strategic leadership, timely evidence-based guidance, and access to medical countermeasures for the most at-risk groups in affected countries.
We are working with a broad range of international, regional, national and local partners and networks to enhance coordination across key areas of preparedness, readiness and response.
This includes engagement with the Act-A Principals group; the Standing Committee on Health Emergency Prevention, Preparedness and Response; the R&amp;D Blueprint for Epidemics; and the i-MCM Net.
WHO regional offices have also established Incident Management Support Teams – IMSTs- to lead preparedness and response activities, and we are significantly scaling up staff in affected countries.
Within the Africa Region, where need is greatest, the WHO Regional Office for Africa, in collaboration with Africa CDC, will jointly spearhead the coordination of mpox response efforts.
Together, WHO AFRO and Africa CDC have agreed on a one-plan, one-budget approach as part of the Africa Continental Mpox Strategic Preparedness and Response Plan.
At the national and sub-national level, health authorities will adapt strategies to current epidemiological trends.
Let me be clear: this new mpox outbreak can be controlled and can be stopped.
Doing so requires concerted action between international agencies and national and local partners, civil society, researchers and manufacturers, and you, our Member States.
As with all global health actions, our approach must adhere to the principles of equity, global solidarity, community empowerment, human rights, and coordination across sectors.
For today's presentation, on behalf of the mpox IMST, Dr Maria Van Kerkhove and Scott Pendergast will present an overview of the temporary recommendations; actions being taken by WHO, Member States and partners; and an overview of the Global Mpox Strategic Preparedness and Response Plan.
Responding to this complex outbreak requires a comprehensive and coordinated international response.
To fund this work and to stop the outbreak as quickly as possible, our initial estimates are that the SPRP requires approximately US$ 135 million over the next six months for the acute phase of the outbreak.
That amount will likely increase as we update the plan in light of growing needs.
A dedicated WHO funding appeal will be released early next week. We are appealing to donors to provide the needed resources, and thank those who have already made pledges to WHO and other partners.
So far, for this mpox outbreak in 2024, we have released about US$ 1.5 million from the WHO Contingency Fund for Emergencies, and we plan to release more in the coming days, until funding from donors for the response comes in.
WHO will coordinate the global response, working closely with each of the affected countries, to prevent transmission, treat those infected, and save lives.
I'd like to close by noting that today's information meeting was requested by members of the Standing Committee on Health Emergency Prevention, Preparedness and Response, which held their first extraordinary meeting last Thursday, just 24 hours after the PHEIC had been declared.
Further updates will be discussed at the fifth meeting of the Standing Committee on the 3rd and 4th of September.
As always, we are grateful for your engagement with today's presentations, and we look forward to your questions, comments and guidance.
I thank you.&nbsp;

WHO Director-General's Opening Remarks At Member States Information Session On Mpox – 23 August 2024

WHO: Côte d'Ivoire Reports First Cases Of Clade II Mpox Since The Start Of The Multi-Country Outbreak In 2022

<a href="https://www.fox2detroit.com/news/mpox-wayne-county-health-department-confirms-first-case-since-2022?taid=66c643be103e400001efc3e9&amp;utm_campaign=trueanthem&amp;utm_medium=trueanthem&amp;utm_source=twitter">https://www.fox2detroit.com/news/mpox-wayne-county-health-department-confirms-first-case-since-2022?taid=66c643be103e400001efc3e9&amp;utm_campaign=trueanthem&amp;utm_medium=trueanthem&amp;utm_source=twitter</a>
&nbsp;
The Wayne County Health Department (WCPH) says it has its first case of mpox since the global outbreak two years ago.
In a release from the WCPH, a case of MPOX was confirmed in a resident in the county – but says there is a low risk to the public due to the nature of how MPOX is spread.
The WCPH is awaiting the specific virus type and said that there have been no new cases of the new strain of mpox (Clade 1 type) that are linked to an outbreak in sub-Saharan Africa. The World Health Organization declared a global health emergency due to the nature of the outbreak in the Democratic Republic of Congo where there have been over 14,000 cases and 524 deaths.
Mpox does not spread through the air between people, though an individual with mpox is contagious for a total of 2-4 weeks.&nbsp;
Symptoms include flu-like symptoms including fevers, muscle aches, swollen lymph nodes, fatigue, and respiratory symptoms. There's also a rash that resembles pimples or blisters and symptoms start within 1 days after exposure.
The health department is recommending vaccines for those at risk of exposure. Taken four weeks apart, two doses are needed for full protection.

'Mpox In Wayne County: Health Department Confirms First Case Since 2022' - Fox 2 Detroit

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Vaccine Group Gavi Says It Has Up To $500M Available For Mpox Response

HC Wainwright &amp; Co. analyst Edward White reiterates Chimerix (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CMRX#NASDAQ">CMRX</a>) with a Buy and maintains $11 price target.

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HC Wainwright & Co. Reiterates Buy on Chimerix, Maintains $11 Price Target

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WHO Says Expert Committee Will Propose Adoption Of Mpox Vaccines Under Emergency Use Listing Around Mid Sept

<a href="https://x.com/i/broadcasts/1kvJpbgRNWgKE" title="https://x.com/i/broadcasts/1kvJpbgRNWgKE">https://x.com/i/broadcasts/1kvJpbgRNWgKE</a>

WHO Director-General Tedros Adhanom Ghebreyesus Says Mpox Is Public Health Emergency Of International Concern

Chimerix (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CMRX#NASDAQ">CMRX</a>) reported quarterly losses of $(0.23) per share which met the analyst consensus estimate. This is a 9.52 percent decrease over losses of $(0.21) per share from the same period last year. The company reported quarterly sales of $129.000 thousand which beat the analyst consensus estimate of $62.500 thousand by 106.40 percent. This is a 396.15 percent increase over sales of $26.000 thousand the same period last year.

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Earnings Beats

Chimerix Q2 2024 GAAP EPS $(0.23), Inline, Sales $129.000K Beat $62.500K Estimate

<a href="https://www.axios.com/2024/08/05/mpox-who-warning-africa">https://www.axios.com/2024/08/05/mpox-who-warning-africa</a>
The World Health Organization is weighing discussions on whether to declare an international public health emergency as a deadlier <a href="https://www.axios.com/2022/11/28/who-renames-monkeypox-mpox">strain of mpox</a> spreads in Africa.
Why it matters: Vaccines and public health surveillance could control the virus, which is killing about 3% of those infected with a new strain in Africa this year and spreading via sex, Science <a href="https://link.axios.com/click/36297630.7565/aHR0cHM6Ly93d3cuc2NpZW5jZS5vcmcvY29udGVudC9hcnRpY2xlL2RlYWRsaWVyLXN0cmFpbi1tcG94LXNwcmVhZHMtbW9yZS1hZnJpY2FuLWNvdW50cmllcz91dG1fc291cmNlPW5ld3NsZXR0ZXImdXRtX21lZGl1bT1lbWFpbCZ1dG1fY2FtcGFpZ249bmV3c2xldHRlcl9heGlvc3ZpdGFscyZzdHJlYW09dG9w/58dbf539d4cd6656658b5760Bd5c54c13">reports</a>.
Driving the news: WHO director-general Tedros Adhanom Ghebreyesus wrote Sunday on X that he's considering convening an advisory committee to discuss whether an emergency should be declared.
<ul>
<li>Local governments and partners are scaling up a response, but more funding and support are needed, <a href="https://link.axios.com/click/36297630.7565/aHR0cHM6Ly94LmNvbS9EclRlZHJvcy9zdGF0dXMvMTgyMDAzOTY2MzU1OTUzMjc4MT91dG1fc291cmNlPW5ld3NsZXR0ZXImdXRtX21lZGl1bT1lbWFpbCZ1dG1fY2FtcGFpZ249bmV3c2xldHRlcl9heGlvc3ZpdGFscyZzdHJlYW09dG9w/58dbf539d4cd6656658b5760Be64a21b5">he wrote</a>.</li>
<li>Mpox — previously known as monkeypox — has risen by 160% in Africa this year compared with 2023, according to the <a href="https://link.axios.com/click/36297630.7565/aHR0cHM6Ly9hZnJpY2FjZGMub3JnL25ld3MtaXRlbS9tcG94LXNpdHVhdGlvbi1pbi1hZnJpY2EvP3V0bV9zb3VyY2U9bmV3c2xldHRlciZ1dG1fbWVkaXVtPWVtYWlsJnV0bV9jYW1wYWlnbj1uZXdzbGV0dGVyX2F4aW9zdml0YWxzJnN0cmVhbT10b3A/58dbf539d4cd6656658b5760B38b98f03">Africa Centers for Disease Control and Prevention</a>.</li>
<li>While the vast majority of cases are in the Democratic Republic of the Congo, outbreaks have been reported in 15 countries.</li>
</ul>
Context: Less than 1% of infected people died during the global mpox <a href="https://www.axios.com/2023/05/11/mpox-global-health-emergency-who">emergency in 2022</a>.
<ul>
<li>Researchers are examining how well mpox vaccines can work after people have become infected.</li>
</ul>

'WHO Warns On Deadlier Strain Of Mpox' - Axios

Dordaviprone is an oral, first-in-class small molecule imipridone that selectively binds to the G-protein coupled dopamine receptor D2 (DRD2) and the mitochondrial protease ClpP.&nbsp;

Guidance

Chimerix Expects Dordaviprone Interim Overall Survival Data In 2025 And Final OS Data In 2026

Chimerix (NASDAQ:<a class="ticker" href="https://www.benzinga.com/stock/CMRX#NASDAQ">CMRX</a>) reported quarterly losses of $(0.25) per share which missed the analyst consensus estimate of $(0.21) by 19.05 percent. This is a 4.17 percent decrease over losses of $(0.24) per share from the same period last year.

Earnings Misses

Chimerix Q1 2024 GAAP EPS $(0.25) Misses $(0.21) Estimate

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WHO official says mpox is 'not the new COVID,' calls for coordinated response

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Bavarian Nordic rebounds as new mpox vaccine order boosts outlook

Mpox stocks in focus as Thailand reports first case in Asia linked to new strain

WHO reportedly greenlights mpox vaccine purchases before approval

UNICEF issues emergency tender to secure mpox vaccines

Bavarian Nordic stock slides on Moderna mpox vaccine study

Morocco reports first mpox case amid ongoing global outbreak

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Press Releases

Chimerix Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

Chimerix to Report First Quarter 2024 Financial Results and Provide an Operational Update on May 1, 2024

Chimerix Reports First Quarter 2024 Financial Results and Provides Operational Update

Chimerix to Participate in Fireside Chat at Jefferies Global Healthcare Conference

Chimerix to Report Second Quarter 2024 Financial Results and Provide an Operational Update on August 13, 2024

Rapid Advancements of Innovative Antiviral – COVID-19 Drugs Generating Major Growth in Global Antiviral Drugs Market

Chimerix Reports Second Quarter 2024 Financial Results and Provides Operational Update

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Chimerix (NASDAQ:CMRX) Stock, Quote.Headers.trade-ideas