| Nov 2, 2026 | Christopher Horan | CHIEF TECH OPERATIONS OFFICER | SELL | 10.423K | $4.18 | $44K |
| Nov 2, 2026 | Jennifer Bush | COO, CLO, COMPLIANCE OFFICER | SELL | 8.439K | $4.18 | $35K |
| Nov 2, 2026 | Subhashis Banerjee | CHIEF MEDICAL OFFICER | SELL | 1.110K | $4.18 | $5K |
| Nov 2, 2026 | Fred Aslan | CHIEF EXECUTIVE OFFICER | SELL | 62.178K | $4.18 | $260K |
| Oct 6, 2026 | Fred Aslan | CHIEF EXECUTIVE OFFICER | SELL | 23.463K | $7.20 | $169K |
| Oct 5, 2026 | Christopher Horan | CHIEF TECH OPERATIONS OFFICER | SELL | 10.340K | $6.84 | $71K |
| Oct 5, 2026 | Jennifer Bush | COO, CLO, COMPLIANCE OFFICER | SELL | 8.370K | $6.84 | $57K |
| Oct 5, 2026 | Subhashis Banerjee | CHIEF MEDICAL OFFICER | SELL | 1.099K | $6.84 | $8K |
| Oct 5, 2026 | Fred Aslan | CHIEF EXECUTIVE OFFICER | SELL | 61.696K | $6.84 | $422K |
| Sep 8, 2026 | Fred Aslan | CHIEF EXECUTIVE OFFICER | SELL | 23.429K | $10.92 | $256K |
| Sep 3, 2026 | Christopher Horan | CHIEF TECH OPERATIONS OFFICER | SELL | 10.366K | $11.16 | $116K |
| Sep 3, 2026 | Jennifer Bush | COO, CLO, COMPLIANCE OFFICER | SELL | 8.391K | $11.16 | $94K |
| Sep 3, 2026 | Subhashis Banerjee | CHIEF MEDICAL OFFICER | SELL | 1.100K | $11.16 | $12K |
| Sep 3, 2026 | Fred Aslan | CHIEF EXECUTIVE OFFICER | SELL | 61.888K | $11.16 | $690K |
| Aug 27, 2026 | Subhashis Banerjee | CHIEF MEDICAL OFFICER | SELL | 2.916K | $6.96 | $89K |
| Aug 18, 2026 | Subhashis Banerjee | CHIEF MEDICAL OFFICER | SELL-OPTIONS | — | $6.96 | $4K |
| Jul 29, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 45.768K | $9.96 | $456K |
| Jul 24, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 41.319K | $9.99 | $413K |
| Jul 21, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 264.586K | $9.76 | $2.6M |
| Jul 16, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 160.354K | $8.93 | $1.4M |
| Jul 10, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 21.654K | $8.96 | $194K |
| Jun 25, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 32.876K | $8.89 | $292K |
| Jun 12, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 531.326K | $8.66 | $4.6M |
| Jun 9, 2026 | RA CAPITAL MANAGEMENT LP, RA Capital Healthcare Fund LP, RA Capital Nexus Fund LP, RA Capital Nexus Fund III LP, Peter Kolchinsky, Rajeev Shah | DIRECTOR | BUY | 1.028M | $7.44 | $7.7M |
| May 19, 2026 | Heather Raymon | SVP, RESEARCH AND DEVELOPMENT | SELL | 3.095K | $9.01 | $28K |
| May 19, 2026 | Christopher Horan | CHIEF TECH OPERATIONS OFFICER | SELL | 7.002K | $9.01 | $63K |
| May 19, 2026 | Jennifer Bush | COO, CLO, COMPLIANCE OFFICER | SELL | 8.790K | $9.01 | $79K |
| May 19, 2026 | Subhashis Banerjee | CHIEF MEDICAL OFFICER | SELL | 7.037K | $9.01 | $63K |
| May 19, 2026 | Fred Aslan | CHIEF EXECUTIVE OFFICER | SELL | 27.116K | $9.01 | $244K |
