Gainers
- Bio-Path Holdings Inc BPTH shares surged 160.46 percent to close at $12.02 on Wednesday after the company's Phase 2 trial of BP1001 for the treatment of acute myeloid leukemia demonstrated 'meaningful clinical improvement' with an 'excellent' patient safety profile.
- OHR Pharmaceutical, Inc. OHRP shares rose 44.19 percent to close at $3.10 on Wednesday.
- Aytu Bioscience Inc AYTU gained 29.09 percent to close at $1.42 after the company announced an agreement with SUDA Pharmaceuticals to distribute ZolpiMist outside of the US and Canada.
- Proteon Therapeutics, Inc. PRTO rose 21.48 percent to close at $3.62.
- Abercrombie & Fitch Co. ANF gained 20.37 percent to close at $25.70 following upbeat Q4 results.
- Diffusion Pharmaceuticals Inc. DFFN rose 18.16 percent to close at $4.49.
- Four Seasons Education (Cayman) Inc. FEDU rose 14.95 percent to close at $2.46.
- J.Jill, Inc. JILL rose 14.63 percent to close at $6.74 after the company reported better-than-expected Q4 EPS and declared a special dividend of $1.15 per share.
- Dogness (International) Corporation DOGZ gained 13.53 percent to close at $3.86.
- Zayo Group Holdings Inc ZAYO climbed 12.58 percent to close at $27.48 after the company's board announced it is evaluating strategic alternatives.
- The Stars Group Inc. TSG climbed 12.41 percent to close at $17.66 after reporting Q4 results. The company also provided FY19 EPS guidance of $1.87-$2.11 and sales guidance of $2.64 billion-$2.77 billion.
- Altimmune, Inc. ALT rose 12.27 percent to close at $3.02.
- DPW Holdings Inc DPW shares gained 11.76 percent to close at $0.0893 after the company announced it has reduced total debt by $3 million in 2019 so far.
- Chiasma, Inc. CHMA climbed 11.24 percent to close at $5.84.
- Avalon GloboCare Corp. AVCO gained 9.8 percent to close at $3.92.
- AeroVironment, Inc. AVAV rose 9.4 percent to close at $83.95 on better-than-expected third-quarter earnings.
- Carbonite, Inc. CARB gained 8.69 percent to close at $23.77.
- PlayAGS, Inc. AGS climbed 8.66 percent to close at $26.35 after the company reported better-than-expected Q4 sales results.
- Fuwei Films (Holdings) Co., Ltd. FFHL climbed 7.66 percent to close at $2.53.
- ERYTECH Pharma S.A. ERYP gained 7.11 percent to close at $9.64. ERYTECH Pharma is expected to report Q4 results on March 12.
- LyondellBasell Industries NV LYB gained 6.11 percent to close at $89.26 after Goldman Sachs upgraded the company's stock from Neutral to Buy.
- Aon plc AON rose 4.3 percent to close at $164.00 after the company issued a press release indicating it is not pursuing business combination with Willis Towers Watson. On Tuesday, the company said it was in the early stages of considering a merger.
Losers
- Nio Inc - ADR NIO shares dropped 21.16 percent to close at $8.01 following Q4 results. Although the company beat sales estimates, it terminated its plan for a Shanghai manufacturing plant and said it expects a greater-than-anticipated sequential decrease in deliveries.
- Valeritas Holdings Inc VLRX shares tumbled 19.97 percent to close at $0.4399 on Wednesday after the company reported mixed Q4 earnings and issued Q1 sales guidance below consensus estimates.
- Qutoutiao Inc. QTT shares dropped 19.94 percent to close at $12.53 after the company reported a wider net loss compared to Q4 last year.
- The9 Limited NCTY shares fell 19.56 percent to close at $1.81 on Wednesday.
- Fuling Global Inc. FORK shares declined 17.16 percent to close at $2.22.
- Synthorx, Inc. THOR dropped 16.91 percent to close at $15.38.
- G1 Therapeutics, Inc. GTHX fell 16.42 percent to close at $17.31.
- InnerWorkings, Inc. INWK shares fell 16.16 percent to close at $4.15 after the company reported Q4 results, and announced extension and expansion of partnership with Beam Suntory.
- Viomi Technology Co., Ltd VIOT dropped 15.9 percent to close at $9.31.
- LiveXLive Media, Inc. LIVX dipped 14.47 percent to close at $5.26.
- Capital Senior Living Corporation CSU shares declined 14.13 percent to close at $3.89.
- Materialise NV MTLS shares declined 13.02 percent to close at $16.04 following downbeat quarterly earnings.
- Aquinox Pharmaceuticals, Inc. AQXP shares dropped 12.59 percent to close at $2.36.
- Gridsum Holding Inc. GSUM tumbled 12.13 percent to close at $3.84.
- Trupanion, Inc. TRUP fell 12.03 percent to close at $26.55.
- Daxor Corporation DXR shares slipped 12.02 percent to close at $15.88.
- Endologix, Inc. ELGX dropped 11.82 percent to close at $5.82. Endologix said the ratio of its previously-announced reverse stock split of its outstanding shares has been fixed at 1-for-10. Beginning with the opening of trading March 6, the shares will trade on the NASDAQ on a reverse stock split-adjusted basis.
- Ligand Pharmaceuticals Incorporated LGND shares fell 11.68 percent to close at $106.52 after reporting the sale of Promacta assets and royalty for $827 million.
- Unity Biotechnology, Inc. UBX dipped 11.15 percent to close at $9.08 following Q4 results.
- Sarepta Therapeutics, Inc. SRPT fell 11.12 percent to close at $132.25. Sarepta priced its 2.6 million share offering at $144 per share.
- Renewable Energy Group Inc REGI fell 10.38 percent to close at $24.00 after the company reported lower-than-expected Q4 sales.
- Owens & Minor, Inc. OMI dropped 10.29 percent to close at $4.71.
- Chico's FAS, Inc. CHS fell 10.28 percent to close at $5.41 after the company reported comparable sales were down 3.5 percent in Q4.
- Replimune Group, Inc. REPL tumbled 10.17 percent to close at $11.83.
- Veeco Instruments Inc. VECO dropped 10.12 percent to close at $10.92 after Stifel Nicolaus downgraded the company's stock from Buy to Hold and announced a price target of $12 per share.
- MDC Partners Inc. MDCA fell 10.09 percent to close at $2.85.
- Abeona Therapeutics Inc. ABEO shares declined 9.96 percent to close at $7.05.
- Vivint Solar, Inc. VSLR dropped 9.68 percent to close at $4.76 after the company reported worse-than-expected Q4 EPS and sales results.
- JinkoSolar Holding Co., Ltd. JKS fell 9.2 percent to close at $16.67.
- United Natural Foods Inc UNFI fell 8.53 percent to close at $13.73. United Natural Foods reported better-than-expected Q2 earnings and issued strong full-year forecast.
- General Electric Company GE dropped 7.89 percent to close at $9.11 after company on Tuesday said it expects to face headwinds for a couple of years and will see even greater negative free cash flow this year.
- The Meet Group, Inc. MEET fell 7.74 percent to close at $5.48 after the company reported Q4 results.
- Cardlytics Inc CDLX fell 7.17 percent to close at $17.09 despite reporting a fourth-quarter earnings beat. The company issued weak first-quarter sales guidance.
- Kandi Technologies Group, Inc. KNDI fell 6.72 percent to close at $7.36.
- Willis Towers Watson Public Limited Company WLTW fell 6.13 percent to close at $170.88 following Aon's decision to no longer pursue a merger with the company.
- Alnylam Pharmaceuticals, Inc. ALNY fell 4.1 percent to close at $84.75 after the company announced that four of its secondary endpoints did not meet the hierarchical threshold for significance in a Phase 3 study of givosiran; many patients also reported serious adverse events.
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