22 Stocks Moving In Wednesday's Pre-Market Session

Gainers

• Retrophin Inc RTRX rose 25.6 percent to $20.49 in the pre-market trading session as the company disclosed that its Phase 2 DUET study of sparsentan achieved primary efficacy endpoint.
• Applied Optoelectronics Inc AAOI shares rose 20.5 percent to $20.98 in pre-market trading as the company lifted its Q3 forecast.
• Francesca's Holdings Corp FRAN rose 14.4 percent to $16.01 in pre-market trading after the company reported better-than-expected Q2 results and lifted its FY16 guidance.
• Bioline RX Ltd BLRX shares rose 13.2 percent to $1.020 in pre-market trading as the company announced a collaboration with Genentech to investigate combination of BL-8040 with Atezolizumab.
• Agios Pharmaceuticals Inc AGIO shares rose 11.7 percent to $41.70 in pre-market trading as the company disclosed that its partner Celgene Corporation CELG will submit a new drug application to the FDA for enasidenib based on ongoing Phase 1/2 study.
• Organovo Holdings Inc ONVO shares rose 9.1 percent to $4.30 in pre-market trading after the company reported the initiation of commercial contracting for its ExVive Human Kidney tissue.
• Progenics Pharmaceuticals, Inc. PGNX rose 7.5 percent to $6.62 in pre-market trading. Valeant Pharmaceuticals Intl Inc and Progenics reported the U.S. commercial launch of FDA-approved Relistor tablets.
• Chipotle Mexican Grill, Inc. CMG rose 5.8 percent to $438.00 in the pre-market trading after Bill Ackman’s Pershing Square disclosed a 9.9 percent stake in the company. It should be noted that the 2,882,463 shares position has an activist nature, as suggested by the 13D SEC filing.
• Western Digital Corp WDC rose 5.1 percent to $49.95 in pre-market trading after the company increased its earnings and revenue forecast for the first quarter.
• Ceragon Networks Ltd CRNT rose 4 percent to $2.86 in pre-market trading after gaining 7.84 percent on Tuesday.
• Valeant Pharmaceuticals Intl Inc VRX rose 2.3 percent to $30.16 in pre-market trading following Relistor tablets launch news.

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Losers

• Sigma Designs Inc SIGM shares fell 12.1 percent to $7.30 in the pre-market trading session. Sigma Designs reported stronger-than-expected quarterly earnings.
• Sprouts Farmers Market Inc SFM fell 11 percent to $20.30 in pre-market trading as the company lowered its full-year forecast and announced a $250 million buyback plan.
• HD Supply Holdings Inc HDS shares fell 10.6 percent to $32.40 in pre-market trading as the company reported below than expected results for the second quarter.
• Summit Midstream Partners LP SMLP fell 7.9 percent to $22.90 in pre-market trading. Summit Midstream reported an offering of 5.5 million common shares.
• Dave & Buster's Entertainment, Inc. PLAY shares fell 6.9 percent to $43.10 in pre-market trading. Dave & Buster's reported better-than-expected results for its second quarter, but issued a weak sales forecast.
• Catalent Inc CTLT shares fell 6.7 percent to $23.60 in pre-market trading. Catalent announced a secondary offering of 19 million shares common stock.
• Casey's General Stores Inc CASY shares fell 6.2 percent to $125.00 in pre-market trading after the company posted weak earnings for its first quarter on Tuesday.
• Advanced Micro Devices, Inc. AMD shares fell 4 percent to $7.05 in pre-market trading. AMD reported a public offering of $600 million in common stock.
• Whole Foods Market, Inc. WFM shares fell 3.1 percent to $29.75 in pre-market trading after declining 0.26 percent on Tuesday.
• Ollie's Bargain Outlet Holdings Inc OLLI shares fell 2.1 percent to $26.65 in pre-market trading. Ollie's Bargain Outlet reported a secondary offering of 13.725 million shares.
• Callon Petroleum Company CPE shares fell 2 percent to $15.00 in pre-market trading. Callon Petroleum priced its upsized 26 million share common stock offering for gross proceeds of $379.6 million.