Alnylam Presents New Pre-clinical Data on RNAi Therapeutics at American Heart Association Meeting

-- Alnylam Pharmaceuticals ALNY announced today that it has presented new pre-clinical data from two RNAi therapeutic programs for cardiovascular disease, including: ALN-PCSsc, an RNAi therapeutic targeting PCSK9 for the treatment of hypercholesterolemia; and ALN-ANG, an RNAi therapeutic targeting ANGPTL3 for the treatment of genetic forms of mixed hyperlipidemia and severe hypertriglyceridemia. These data were presented at the American Heart Association (AHA) Scientific Sessions held November 16 – 20, 2013 in Dallas, Texas. In a presentation titled “A Subcutaneous Platform for RNAi Therapeutics Targeting Metabolic Diseases: PCSK9 and ANGPTL3,” Alnylam scientists and collaborators presented updated non-human primate (NHP) data showing that subcutaneous administration of See full press release