Aeterna Zentaris Inc. AEZS today announced that final Phase 2 data for
perifosine, its oral AKT inhibitor, combined with sorafenib in patients
with relapsed/refractory lymphomas, will be presented at the upcoming
American Society of Hematology ("ASH") annual meeting in Atlanta,
Georgia, December 8-11, 2012. Data will be disclosed during a poster
presentation by Anna Guidetti, MD, of the Fondazione IRCCS Instituto Nazionale Tumori, Milan, Italy.
Abstract #3679:
"Dual Targeted Therapy with the AKT Inhibitor Perifosine and the
Multikinase Inhibitor Sorafenib in Patients with Relapsed/Refractory
Lymphomas: Final Results of a Phase 2 Trial", A Guidetti, S. Viviani, A. Marchiano, A. Dodero, L. Farina, S.L.
Locatelli, D. Russo, P. Bulian, R. Sorasio, M. Di Nicola, L. Giordano,
P. Corradini, A.M. Gianni, C. Carlo-Stella.
Poster Session #624:
"Lymphoma-Therapy with Biologic Agents, Excluding Pre-Clinical Models:
Poster III"
Date & Time:
Monday, December 10, 2012, from 6 pm to 8 pm (Eastern)
Venue:
Georgia World Congress Center, Hall B1-B2, Level 1, Building B
About Perifosine
Perifosine is a novel, oral anticancer treatment that inhibits Akt
activation in the phosphoinositide 3-kinase (PI3K) pathway. It has been
granted orphan drug and orphan medicinal product designations for
multiple myeloma ("MM") from the FDA and the European Medicines Agency
("EMA"), respectively. Perifosine
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