Amicus Therapeutics Announces Publication of BLISS Quantitative Histology Method in Archives of Pathology & Laboratory Medicine

Amicus Therapeutics, Inc.

today announced that a manuscript describing the Barisoni Lipid Inclusion Scoring System (BLISS) has been published in the July 2012 issue of Archives of Pathology & Laboratory Medicine. The manuscript titled, "A Novel, Quantitative Method to Evaluate GL-3 Inclusions in Renal Peritubular Capillaries by Virtual Microscopy in Patients with Fabry Disease,"1 is currently available online. BLISS improves the ability to detect and quantify changes in globotriaosylceramide (GL-3) peritubular capillary (PTC) inclusions - also referred to as interstitial capillaries - in females and males with Fabry disease. GL-3 is the lipid substrate that accumulates in tissues affected by Fabry disease, including the kidney. BLISS was developed by Dr. Laura Barisoni while she was an Associate Professor in Pathology and Medicine at the New York University School of Medicine, in collaboration with Amicus. Dr. Barisoni is currently a Voluntary Associate Professor in Pathology at the University of Miami.