Voyager Therapeutics Prioritizes Pipeline With Cash Runway Into 2024

  • Voyager Therapeutics Inc (NASDAQ:VYGR) unveiled its prioritized therapeutic pipeline focusing on tau antibody for Alzheimer's disease and gene therapies for GBA1 Parkinson's and SOD1 ALS.
  • For GBA1 Parkinson's, a non-human primate (NHP) capsid evaluation study is currently underway. 
  • Voyager intends to select a development candidate in 1H of 2023, initiate a dose range finding study in NHPs in 2H of 2023, and initiate GLP toxicology studies in 2024. 
  • Voyager anticipates an IND filing in 2025.
  • For SOD1 gene silencing, an NHP capsid evaluation study is currently underway. The company intends to select a development candidate in 2022, complete an NHP dose range finding study in 2023, initiate GLP toxicology studies in 1H of 2024, and file an IND in 2024.
  • On the partnership front, the company believes that Pfizer Inc (NYSE: PFE) and Novartis AG (NYSE: NVS) TRACER capsid collaborations are going well with option exercise decisions upcoming in Q4 2022 and Q1 2023, respectively.
  • Voyager expects that its cash, cash equivalents, and marketable securities will be sufficient to meet Voyager's planned operating expenses and capital expenditure requirements into 2024.
  • Price Action: VYGR shares are down 6.02% at $7.02 during the market session on the last check Friday.
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