NeuroSense Shares Surge On Encouraging Data From Alzheimer's-Associated Biomarker Study

  • NeuroSense Therapeutics Ltd NRSN has announced results from a biomarker study to evaluate the potential of CogniC, a combination drug for Alzheimer's disease (AD).
  • Earlier this week, NeuroSense reported results from a stage III ALS Biomarker study evaluating PrimeC.
  • Preliminary results showed that levels of disease-related biomarkers in people with ALS were unchanged, in contrast to a statistically significant decline in biomarkers when PrimeC was administered.
  • NeuroSense's biomarker study indicates that CogniC's mechanism of action may effectively target the pathways involved in the disease, such as miRNA dysregulation, lysosomal dysfunction, and impaired autophagy. 
  • Additionally, hallmarks of AD were detected, such as increased levels of amyloid-β (Aβ) and intracellular aggregates of tau protein among the panel of biomarkers evaluated.
  • Preliminary results revealed high levels of TDP-43 in people who suffer from AD compared to the healthy control group. 
  • NeuroSense says that CogniC has already been shown to impact TDP-43 in a Phase 2a clinical trial biomarker study in amyotrophic lateral sclerosis (ALS).
  • NeuroSense is conducting its AD biomarker study using Neuron-Derived Exosomes to observe key alterations in biomarkers. 
  • Price Action: NRSN shares are up 62.4% at $4.45 during the premarket session on the last check Thursday.

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