NanoViricides Starts Drug Development Program For Recent Cases Of Unexplained Pediatric Hepatitis

  • NanoViricides Inc NNVC has initiated a program to screen its library of broad-spectrum antiviral nanoviricides against human Adenovirus 41 Type F (hAd41-F), believed to be strongly associated with the occurrence of severe hepatitis syndrome in some children.
  • The company says its top priority remains to initiate human trials of its SARS-CoV-2 drug candidate NV-CoV-2 to combat COVID-19. 
  • NanoViricides expects filing a clinical trial application for COVID-19 to occur relatively soon, although the timelines are outside the company's control.
  • Related: EXCLUSIVE: NanoViricides Develops Chewable Pills, Lung Inhalation Formulations For COVID-19 Candidate.
  • The company believes it can successfully develop a drug candidate against hAd41-F relatively quickly if one or more of its existing pipeline candidates or other nanoviricide candidates in its drug candidate library is effective. 
  • NanoViricides is developing an antiviral assay for testing these drug candidates against hAd41-F infection in cell cultures in its virology facility.
  • It is thought that a combination of prior SARS-CoV-2 exposure or infection, along with current hAd41-F infection, may be responsible for hepatitis cases. However, no definitive cause of this severe hepatitis syndrome has been established. 
  • As reported by NBC News online, the number of cases worldwide has risen to 450 as of May 15. 
  • Related: Six US States Probing Mysterious Liver Inflammation In Kids: Bloomberg.
  • Price Action: NNVC shares are up 16.10% at $1.50 during the market session on the last check Monday.
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