Sanofi SA's (NASDAQ:SNY) Q4 FY21 sales grew 4.1% to €9.99 billion, +6.5% (+4.1% on constant exchange rates).

• Business EPS came in at €1.38, compared with €1.22 a year ago.
• For FY21, Business EPS rose by 15.5% at CER, while the company had guided for a rise of 14%.
• The gross profit margin expanded 240 basis points to 69.5%, and the business operating profit margin increased from 21.9% to 22.6%.
• The decline in flu vaccines weighed on sales in Q4. Net sales from Vaccines fell 6.5% at CER despite strong Europe sales, reflecting low U.S. influenza vaccination rates, which resulted from the prioritization of COVID-19 booster vaccinations.
• Influenza vaccines sales decreased 12.4%, reaching €1.09 billion.
• Q4 FY21 Pharmaceutical sales increased 7.4% to €6.9 billion, mainly driven by the Specialty Care portfolio (up 21.3%) with the continued strong performance of Dupixent while sales in General Medicines decreased 3.8%. Dupixent sales increased 53.1% to €1.55 billion.
• Sanofi expects to report the late-stage trial results for its COVID-19 vaccine, developed with GlaxoSmithKline Plc (NYSE:GSK), in Q1 FY22. 
• The companies said in December that the shot has promise as a booster.
• Guidance: Sanofi, hoping for a comeback after losing ground in the COVID-19 jab race, said it aimed to increase its business EPS in the "low double-digit" at CER in 2022.
• Price Action: SNY shares closed lower by 0.15% at $52.46 on Thursday.