- Merck & Co Inc MRK and Ridgeback Biotherapeutics have initiated the Phase 3 MOVe-AHEAD trial to evaluate molnupiravir, an investigational oral antiviral therapeutic, for the prevention of COVID-19 infection.
- The global study enrolls individuals who are at least 18 years of age and reside in the same household as someone with confirmed SARS-CoV-2 infection with symptoms. The trial will enroll approximately 1,332 participants.
- Related Content: Merck, Ridgeback Highlight Interim Molnupiravir Data In Non-Hospitalized COVID-19 Patients.
- Participants are not eligible for the trial if they have received the first dose of a COVID-19 vaccine more than seven days before enrollment, have previously had COVID-19, or are showing any signs or symptoms of COVID-19.
- The trial's primary endpoints include a percentage of participants with COVID-19 through Day 14, participants with an adverse event, and those who discontinued study intervention due to an adverse event.
- The safety and efficacy of molnupiravir is currently under evaluation in Part 2 of the ongoing MOVe-OUT trial in non-hospitalized adult patients with mild to moderate COVID-19.
- Data from the study is expected in the second half of 2021.
- Read Next: Merck Inks Molnupiravir Supply Pact With US Government For COVID-19.
- Price Action: MRK shares are down 0.03% at $76.27 during the premarket session on the last check Wednesday.
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