Market Overview

Acasti Delays Data Readout For Drug To Treat Elevated Triglycerides

Acasti Delays Data Readout For Drug To Treat Elevated Triglycerides

Micro-cap biopharma Acasti Pharma Inc (NASDAQ: ACST) issued an update regarding a delay in a clinical readout.

Shares came under significant selling pressure mid-session Monday, losing roughly 60% at one point.

Data Delayed

Acasti said late Monday it's postponing the release of top-line results for the TRILOGY 1 pivotal Phase 3 study of CaPre to January, citing an unexpected delay in data processing and transfer from the central testing laboratory to the statistical consultants for independent and external validation.

Earlier, the company had a December timeframe for the readout, while results from the second Phase 3 study dubbed TRILOGY 2 was due in January.

CaPre, a highly purified omega-3 phospholipid concentrate derived from krill oil, is being developed to treat severe hypertriglyceridemia, a metabolic condition that contributes to increased risk of cardiovascular disease and pancreatitis.

See Also: 10 Biotech M&A Targets Under The Scanner For 2020

Company Underplays The Delay

Acasti is a single-trick pony, having only one drug in its pipeline.

The company also said it has "no material update to provide at this time beyond the above timing update and independent and external validation exercise that is underway."

The last patient enrolled in the study is expected to complete the final visit in early January 2020, it added.

Acasti said the top-line results will include a primary endpoint, showing the overall impact of CaPre on lowering triglycerides after 12 weeks compared to placebo, as well as safety and tolerability data.

"As previously disclosed, subgroup analyses of certain key secondary (LDL) and exploratory markers (HbA1c) will be dependent on combining results from both studies,and would be expected sometime later in the first quarter of 2020," the company added.

Acasti's stock traded lower by 3.4% to $2.10 per share at time of publication.

Posted-In: Biotech News Penny Stocks Markets Trading Ideas Best of Benzinga


Related Articles (ACST)

View Comments and Join the Discussion!
Don't Miss Any Updates!
News Directly in Your Inbox
Subscribe to:
Benzinga Premarket Activity
Get pre-market outlook, mid-day update and after-market roundup emails in your inbox.
Market in 5 Minutes
Everything you need to know about the market - quick & easy.
Daily Analyst Rating
A summary of each day’s top rating changes from sell-side analysts on the street.
Fintech Focus
A daily collection of all things fintech, interesting developments and market updates.
Thank You

Thank you for subscribing! If you have any questions feel free to call us at 1-877-440-ZING or email us at