ENGAGE Randomized Clinical Trial Evaluating Cerdelgafor Treatment-Naïve Patients with Gaucher Disease Type 1 Published in The Journal of the American Medical Association

Genzyme, a Sanofi company, today announced the publication of results from the ENGAGE registration study evaluating Cerdelga® (eliglustat) in treatment-naïve patients with Gaucher disease type 1 in the February 17, 2015 issue of The Journal of the American Medical Association. The ENGAGE study is a Phase 3 randomized, double-blinded, placebo-controlled, multinational registration trial of 40 eligible treatment-naïve patients with Gaucher disease type 1 who had splenomegaly in addition to thrombocytopenia and/or anemia at study entry. Gaucher disease is a genetic disorder in which individuals fail to produce glucocerebrosidase, an important enzyme that breaks down the glycolipid glucocerebroside within lysosomes. In the absence of