Market Overview

Canaccord Previews Biotech Catalysts In The Second Half: Neurological Drugs In Focus

Canaccord Previews Biotech Catalysts In The Second Half: Neurological Drugs In Focus
Related BIIB
Activision Blizzard, Biogen, Expedia, Newmont Mining: 'Fast Money' Picks For January 4
6 Valuable Pipeline Drugs With Upcoming Catalysts
Editas and CRISPR weigh on biotechs, XBI down 3% (Seeking Alpha)
Related NVS
The Daily Biotech Pulse: FDA Panel Backs Amgen's Hypertension Drug, Adamis Allergy Drug Launched In US
The Daily Biotech Pulse: Amgen Slashes Cholesterol Drug Device Prices By 60%, Takeda Completes Shire Purchase
5 Potential Biotech M&A Targets To Watch In 2019 (Seeking Alpha)

The biotech space represents a gold mine of opportunity for investors to multiply their investment returns, courtesy of the volatility generated by market-moving catalysts.

In a note this week, Canaccord Genuity analyst Sumant Kulkarni presented a list of key catalysts for companies in his coverage universe, with those involving neurological disorder drugs dominating the list.

Alzheimer's Disease

Biogen Inc (NASDAQ: BIIB) and partner Eisai will make an oral presentation of Phase 2 results from their Alzheimer's disease candidate BAN2401 at the upcoming Alzheimer's Association International Conference in Chicago on July 25.

The company reported positive top-line results from the Phase 2 study July 5.

Kulkarni expects the data presentation at the AAIC and its potential read-through to remain a focal point over the next several quarters ahead of more Alzheimer's-related events. (See the analyst's track record here.) 

Biogen is also expected to complete enrollment midyear for the Phase 3 study of aducanumab, a human monoclonal antibody for Alzheimer's.

BioXcel Therapeutics Inc (NASDAQ: BTAI) is set to present Phase 1b pharmacokinetic/pharmacodynamic data on its intravenous dex for treating Alzheimer's as well as schizophrenia in the second half of this year. The readouts of the company's Phase 2 open-label proof-of-concept studies for both programs, which are due to start in the second half, are likely to arrive late this year. 

The company will start bridging bioavailability/bioequivalence studies for its sublingual film in the second half of 2018, Kulkarni said.


Intra-Cellular Therapies Inc (NASDAQ: ITCI) is likely to complete a new drug application for its schizophrenia treatment lumateperone in mid-2018.

Parkinson's Disease

Voyager Therapeutics Inc (NASDAQ: VYGR) expects updates from a Type C meeting with the FDA for VY-AADC, its gene therapy for Parkinson's disease, as well as first-patient dosing in the pivotal trial.

Postpartum Depression

SAGE Therapeutics Inc (NASDAQ: SAGE) has an upcoming FDA adcom meeting for its brexanolone IV for treating postpartum depression in Q3 or early Q4. The PDUFA action date is set for Dec. 19.

Rival Marinus Pharmaceuticals Inc (NASDAQ: MRNS) is likely to report data for its ganaxolone IV for women with severe/moderate postpartum depression in Q3/Q4 of 2018.

Spinal Muscular Atrophy

Canaccord expects Biogen's spinal muscular atrophy gene therapy candidate to enter clinical trials in mid-2018.

SMA, caused by a mutation in the survival motor gene 1, affects the motor nerve cells in the spinal cord, which impairs the ability to walk, eat or breathe.

Novartis AG (ADR) (NYSE: NVS)'s Avexis unit is also expected to reveal details on FDA-related developments on its AVSX-101 gene therapy for SMA.

Latest Ratings for BIIB

Dec 2018BTIG ResearchInitiates Coverage OnBuy
Dec 2018Morgan StanleyMaintainsOverweightOverweight
Oct 2018JP MorganMaintainsOverweightOverweight

View More Analyst Ratings for BIIB
View the Latest Analyst Ratings

Posted-In: Canaccord GenuityAnalyst Color Biotech News Previews FDA Analyst Ratings Trading Ideas Best of Benzinga


Related Articles (BIIB + BTAI)

View Comments and Join the Discussion!

Latest Ratings

ADNTRBC CapitalDowngrades16.0
DLPHRBC CapitalDowngrades17.0
MTORRBC CapitalDowngrades19.0
View the Latest Analytics Ratings
Don't Miss Out!
Join Our Newsletter
Subscribe to:
Market in 5 Minutes
Everything you need to know about the market - quick & easy.
Daily Analyst Rating
A summary of each day’s top rating changes from sell-side analysts on the street.
Fintech Focus
Your weekly roundup of hot topics in the exciting world of fintech.
Thank You
for registering for Benzinga’s newsletters and alerts.
• The Daily Analysts Ratings email will be received daily between 7am and 10am.
• The Market in 5 Minutes email will be received daily between 7am and 8am.
• The Fintech Focus email will be received every Friday between 2pm and 5pm.

Wealth And Philanthropy: The World's 10 Richest Aren't The World's 10 Most Generous

Analysts See Limited Upside For Visteon