Top Percentage Gainers and Losers as of 10 am 4/18/11 (AMRN, INVE, THOR, TITN, AONE, HTWR, GKK, CYH, VPHM, KONG)

Best

1) Amarin Corporation

AMRN

: Trading up 79% from Friday's close to $15.70. A positive phase III trial of the company's main product has shares vaulting this morning. The drug, AMR101, significantly lowered triglycerides without causing a rise in “bad” cholesterol. 2) Identive Group

INVE

: Trading up 15.5% from Friday's close to $3.88. 3) Titan Machinery

TITN

: Trading up 14.8% from Friday's close to $30.91. Company reported better than expected earnings. 4) Thoratec

THOR

: Trading up 14.2% from Friday's close to $31.34. Company was upgraded from Neutral to Buy at Lazard. 5) A123 Systems

AONE

: Trading up 8.7% from Friday's close to $5.99.

Worst

1) Gramercy Capital GKK: Trading down 17.6% from Friday's close to $3.35. A two-week extension of the maturity dates of a $240.5 million mortgage loan and a $549.7 million junior and senior mezzanine loans has shares falling.

2) Heartware International HTWR: Trading down 13.57% from Friday's close to $72.52. Positive results for rival Thoratec's THOR heart device has shares plunging.

3) Community Health Systems CYH: Trading down 10% from Friday's close to $28.74.

4) VioPharma VPHM: Trading down 9.5% from Friday's close to $19.73.

5) KongZhong KONG: Trading down 8.2% from Friday's close to $9.90.