Nucor, Altimmune And Some Other Big Stocks Moving Lower On Wednesday - Alcoa (NYSE:AA), Altimmune (NASDAQ

U.S. stocks traded higher, with the Dow Jones gaining around 100 points on Wednesday. Here are some big stocks recording losses in today’s session.

Vintage Wine Estates, Inc. (NASDAQ:VWE) fell 40.5% to $3.29 after the company posted a wider Q4 loss. Telsey Advisory Group and Canaccord Genuity downgraded the stock.
Altimmune, Inc. (NASDAQ:ALT) fell 28.4% to $14.60 after topline results from its 12-week Phase 1b study of pemvidutide in subjects with non-alcoholic fatty liver disease (NAFLD).
POINT Biopharma Global Inc. (NASDAQ:PNT) dropped 14% to $8.75 after the company priced a public offering of 13.9 million shares of common stock at $9 per share.
System1, Inc. (NYSE:SST) fell 13.6% to $8.47.
Shuttle Pharmaceuticals Holdings, Inc. (NASDAQ:SHPH) dropped 11.2% to $36.57 amid post-IPO volatility after the stock began trading in late August.
Century Aluminum Company (NASDAQ:CENX) fell 10% to $7.45.
Consolidated Water Co. Ltd. (NASDAQ:CWCO) declined 9.7% to $17.82 after Janney Montgomery Scott downgraded the stock from Buy to Neutral.
Alcoa Corporation (NYSE:AA) dropped 9.6% to $ 45.39.
Seer, Inc. (NASDAQ:SEER) fell 9.6% to $8.79.
Nucor Corporation (NYSE:NUE) dipped 9% to $123.92 after the company issued Q3 guidance and said, "We expect the steel mills segment earnings to be considerably lower in the third quarter of 2022 as compared to the second quarter of 2022."
Sprinklr, Inc. (NYSE:CXM) dropped 8% to $11.49.
Opendoor Technologies Inc. (NASDAQ:OPEN) dipped 7.7% to $4.2150.
Transocean Ltd. (NYSE:RIG) fell 7.4% to $3.37.
United States Steel Corporation (NYSE:X) declined 7.4% to $20.70.
AppLovin Corporation (NYSE:APP) dropped 6.6% to $24.91.