10 Stocks Moving In Wednesday's Pre-Market Session

Gainers

Repros Therapeutics Inc RPRX shares rose 56.67 percent to $1.280 in pre-market trading after the company Therapeutics reported that patients receiving 6 and 12 mg doses of Proellex achieved significant reduction in excessive menstrual bleeding, the key symptom of uterine fibroids. The findings were part of a small Phase 2b study.

Pain Therapeutics, Inc. PTIE rose 18.48 percent to $2.50 in pre-market trading on news the FDA had accepted REMOXY’s New Drug Application (NDA) for review, setting a PDUFA date of September 25, 2016.

Arrowhead Pharmaceuticals Inc ARWR shares rose 14.07 percent to $6.00 in pre-market trading as the company announced that ARC-520 presentations will be made at The International Liver Congress™ 2016.

Medivation Inc MDVN shares rose 8.68 percent to $49.70 in pre-market trading driven by a report about a "rebuffed takeover approach" from Sanofi SA (ADR) SNY. Bloomberg reported shortly after the closing bell that Medivation, which focuses on treatments for hard-to-cure cancers, is seeking a higher price than initial proposals have indicated. Other suitors are also considering making an offer, people familiar with the matter said.

CSX Corporation CSX rose 3.24 percent to $25.80 in pre-market trading. CSX reported in-line earnings for its first quarter, but the company missed analysts' sales estimates.

JPMorgan Chase & Co. JPM shares rose 2.73 percent to $60.95 in pre-market trading after the bank reported better-than-expected earnings for its first quarter on Wednesday.

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Losers

Clovis Oncology Inc CLVS shares fell 6.60 percent to $13.30 in pre-market trading after dropping 5.44 percent on Tuesday. JP Morgan downgraded Clovis Oncology from Overweight to Neutral and lowered the price target from $42.00 to $15.00.

Randgold Resources Ltd. (ADR) GOLD shares fell 2.38 percent to $95.64 in pre-market trading after rising 1.80 percent on Tuesday.

Valeant Pharmaceuticals Intl Inc VRX shares fell 3.53 percent to $30.85 in pre-market trading on a Wall Street Journal report that a creditor, bond fund Centerbridge, notified the company of its intention to call a default.

Tower Semiconductor Ltd. (USA) TSEM shares fell 3.19 percent to $9.42 in pre-market trading after declining 1.83 percent on Tuesday.