Shire Offers Statement Following AbbVie Announcement, Says Board Will Meet to Consider Offer

Shire plc ("Shire" or the "Company")

notes the announcement by AbbVie Inc.

of a revised conditional non-binding proposal for a cash and share offer for Shire, comprising £22.44 in cash and 0.8568 AbbVie shares per Shire share. Shire confirms that AbbVie did not make the revised proposal to Shire before the announcement. The Board of Shire will meet to consider the proposal and a further announcement will be made in due course. Shareholders are strongly advised to take no action in relation to the AbbVie proposal. There can be no certainty that any firm offer will be made nor as to the terms on which any firm offer might be made. This statement is being made by Shire without the prior agreement or approval of AbbVie.