Discovery Laboratories, Inc.
DSCO today announced the release of data from a new pharmacoeconomic
analysis demonstrating that the previously-reported reduced rate of
reintubation in preterm infants treated with SURFAXIN^® may also result in an
average potential hospital cost savings of $389,247 per 100 treated infants by
reducing the frequency of bronchopulmonary dysplasia (BPD) when compared with
reintubation rates of infants treated with the current global market leading
surfactants, Curosurf^® and Survanta^®. The analysis was presented at the
2012 Hot Topics in Neonatology Annual Meeting held December 2-4 in Washington
D.C. Hot Topics in Neonatology is an internationally recognized medical
meeting dedicated to advancing the practice of neonatology.
The current standard of care for managing preterm infants with respiratory
distress syndrome (RDS) typically requires that the infant undergo intubation
(insertion of a breathing tube into the infant's airway) to allow for
surfactant administration and respiratory support via mechanical ventilation.
If therapy is successful, the breathing tube is removed to allow the infant to
breathe independently. However, over one third of infants have difficulty
breathing independently after the breathing tube is removed and require a
subsequent intubation, or reintubation. Reintubation and extended exposure to
mechanical ventilation is often associated with an increased incidence of
other complications such as BPD – a chronic lung condition that affects some
preterm infants who were at risk for or afflicted with RDS or required
respiratory support via mechanical ventilation during the neonatal period.
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