Why Mid-Cap Corcept Therapeutics Stock Trading Higher On Tuesday?

Zinger Key Points
  • GRACE met its primary endpoint of loss of blood pressure control in the randomized withdrawal phase among relacorilant patients vs. placebo
  • Corcept Therapeutics expects to submit its New Drug Application in the third quarter.
Loading...
Loading...

Tuesday, Corcept Therapeutics Incorporated CORT announced that the GRACE Phase 3 trial of relacorilant in patients with hypercortisolism (Cushing’s syndrome) met its primary endpoint.

In April, Corcept announced that patients in GRACE’s initial, open-label phase exhibited clinically meaningful and statistically significant improvements in hypertension, hyperglycemia, and other symptoms experienced by patients with Cushing’s syndrome. 

Related: Mid-Cap Corcept Therapeutics Reveals Data From Hormonal Disorder Study, FDA Application Submission Expected This Quarter.

Patients who exhibited pre-specified improvements in hypertension, hyperglycemia or both were allowed to enter the trial’s randomized, double-blind withdrawal phase. For 12 weeks, half of the patients continued to receive relacorilant, and half received a placebo. 

GRACE met its primary endpoint of loss of blood pressure control in the randomized withdrawal phase among patients receiving relacorilant compared to placebo (odds ratio: 0.17; p-value: 0.02). 

Consistent with its known safety profile, relacorilant was well-tolerated in both phases of GRACE, with no differences in the randomized withdrawal phase between the relacorilant and placebo groups. 

The company expects to submit its New Drug Application in the third quarter.

Read Next: What’s Going On With Stress Hormone Modulator-Focused Corcept Therapeutics’ Stock Friday?

Price Action: CORT shares are up 11.4% at $30.65 at last check Tuesday.

Photo via Shutterstock

Market News and Data brought to you by Benzinga APIs
Comments
Loading...
Posted In: BiotechEquitiesNewsHealth CareMoversTrading IdeasGeneralBriefsStories That Matterwhy it's moving
Benzinga simplifies the market for smarter investing

Trade confidently with insights and alerts from analyst ratings, free reports and breaking news that affects the stocks you care about.

Join Now: Free!

Loading...