Amarin Touts Positive Data For Its Heart Disease Drug In Current/Former Smokers

  • Amarin Corporation plc AMRN announced that new REDUCE-IT data show that Vascepa/Vazkepa (icosapent ethyl) significantly reduced cardiovascular (CV) events in patients with a history of smoking.
  • In this post hoc exploratory analysis, icosapent ethyl (IPE) treatment significantly reduced the risk of first and total primary composite events in current/former smokers by 23% and in former smokers by 29%, compared to the placebo. 
  • Related: Amarin's New Vascepa Data Shows Significant Reduction In Heart Attack Subtypes.
  • IPE treatment reduced the incidence of CV events in current smokers by 23.8% and former smokers by 23.0% to levels observed in never smokers (25.7%) in the placebo group. 
  • Compared with placebo, IPE use in combined current and former smokers was associated with significant reductions in first primary composite events and total primary composite events.
  • Overall, there were similar estimated rates of first occurrences of CV death, MI, stroke, coronary revascularization, or hospitalization for unstable angina in current smokers (23.8%) and former smokers (23.0%) assigned to IPE compared to the placebo (25.7%).
  • Price Action: AMRN shares closed lower by 2.31% at $1.27 on Friday.
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